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Found 32 with Last Name = 'winiski' and Initial = 'ap'
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataKi:  470nMAssay Description:Inhibitory constant against human steroid sulfatase in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibitory constant against human steroid sulfatase in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  0.150nMAssay Description:Inhibitory activity against human steroid sulfatase in sebocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50118560(CHEMBL262050 | Sulfamic acid 2-adamantan-1-yl-4-ox...)
Affinity DataIC50:  0.340nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  0.75nMAssay Description:Inhibitory activity against human steroid sulfatase expressing in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of human STS in keratinocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory activity against STS in human MCF-7 breast cancer cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50135162(CHEMBL147705 | Sulfamic acid 2-adamantan-1-yl-4-ox...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50135161(CHEMBL359199 | Sulfamic acid 4-oxo-2-(4-pentyl-bic...)
Affinity DataIC50:  11nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50118551(CHEMBL137392 | Sulfamic acid 2-tert-butyl-4-oxo-4H...)
Affinity DataIC50:  22nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  32nMAssay Description:Inhibitory constant against human steroid sulfatase in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50118575(CHEMBL137391 | Sulfamic acid 4-oxo-2-(2,2,3,3-tetr...)
Affinity DataIC50:  45nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50118549(CHEMBL137289 | Sulfamic acid 2-cyclododecyl-4-oxo-...)
Affinity DataIC50:  45nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataIC50:  56nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50118570(CHEMBL137707 | Sulfamic acid 2-(1,1-dimethyl-nonyl...)
Affinity DataIC50:  78nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50118564(CHEMBL136663 | Sulfamic acid 2-adamantan-1-yl-4-ox...)
Affinity DataIC50:  140nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50118574(CHEMBL137119 | Sulfamic acid 4-oxo-2-phenethyl-4H-...)
Affinity DataIC50:  190nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50118567(CHEMBL137692 | Sulfamic acid 2-nonyl-4-oxo-4H-chro...)
Affinity DataIC50:  403nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50035218(CHEMBL61 | PODOFILOX | Podophyllinic acid lactone ...)
Affinity DataIC50:  560nMAssay Description:Binding affinity to pig brain tubulin at 10 uM after 15 mins relative to controlMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50038200(5-[2-(2,5-Dimethoxy-phenyl)-ethyl]-2-hydroxy-benzo...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of pig brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50038199(5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-benzoic ac...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of EGF-R Tyrosine kinase (TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50038203(5-[2-(2,5-Dihydroxy-phenyl)-ethyl]-2-hydroxy-benzo...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of EGF-R Tyrosine kinase (TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50038202(5-((2,5-dihydroxybenzyl)(2-hydroxybenzyl)amino)-2-...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of EGF-R Tyrosine kinase (TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50038205(5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-benzoic ac...)
Affinity DataIC50:  2.44E+4nMAssay Description:Inhibition of EGF-R Tyrosine kinase (TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50038200(5-[2-(2,5-Dimethoxy-phenyl)-ethyl]-2-hydroxy-benzo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGF-R Tyrosine kinase (TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50038206(5-(3,6-Dimethoxy-cyclohexa-1,5-dienylmethoxy)-2-hy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGF-R Tyrosine kinase (TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50038197(5-(2,5-Dimethoxy-benzylamino)-2-hydroxy-benzoic ac...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGF-R Tyrosine kinase (TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50038201(5-(3,6-Dimethoxy-cyclohexa-1,5-dienylmethoxy)-2-hy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGF-R Tyrosine kinase (TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataEC50: >1.00E+5nMAssay Description:Affinity for human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataEC50: >1.00E+5nMAssay Description:Affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataEC50:  3.70E+3nMAssay Description:Affinity for human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataEC50:  2.60E+3nMAssay Description:Affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed