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Found 31 with Last Name = 'winneroski, jr.' and Initial = 'll'
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458383(1-(2-(((3R,5S)-1-((6-fluoro-2-methylbenzo[d]thiazo...)
Affinity DataIC50:  0.214nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458383(1-(2-(((3R,5S)-1-((6-fluoro-2-methylbenzo[d]thiazo...)
Affinity DataIC50:  0.214nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150692(US8987254, 7)
Affinity DataIC50:  0.358nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458387(1-[2-[(3R,5S)-1-[(1S)-1-(6-fluoro-2-methyl-1,3-ben...)
Affinity DataIC50:  0.385nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458387(1-[2-[(3R,5S)-1-[(1S)-1-(6-fluoro-2-methyl-1,3-ben...)
Affinity DataIC50:  0.385nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150690(US8987254, 5)
Affinity DataIC50:  0.450nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458382(1-(2-(((3R,5S)-1-((6-fluoro-2-methylbenzo[d]thiazo...)
Affinity DataIC50:  0.465nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458382(1-(2-(((3R,5S)-1-((6-fluoro-2-methylbenzo[d]thiazo...)
Affinity DataIC50:  0.465nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150687(US8987254, 2)
Affinity DataIC50:  0.482nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458386(1-[2-[(3R,5S)-1-[(1S)-1-(6-fluoro-2-methyl-1,3-ben...)
Affinity DataIC50:  0.495nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458386(1-[2-[(3R,5S)-1-[(1S)-1-(6-fluoro-2-methyl-1,3-ben...)
Affinity DataIC50:  0.495nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150688(US8987254, 3 | US9999624, 3)
Affinity DataIC50:  0.554nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150689(US8987254, 4)
Affinity DataIC50:  0.569nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458385(1-[3-[(3R,5S)-1-[(6-fluoro-2-methyl-1,3-benzothiaz...)
Affinity DataIC50:  0.592nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458385(1-[3-[(3R,5S)-1-[(6-fluoro-2-methyl-1,3-benzothiaz...)
Affinity DataIC50:  0.592nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150686(US8987254, 1 | US9999624, 1)
Affinity DataIC50:  0.610nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150693(US8987254, 8 | US9999624, 9)
Affinity DataIC50:  0.730nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150691(US8987254, 6 | US9999624, 7)
Affinity DataIC50:  0.739nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458384(1-[6-[(3R,5S)-1-[(6-fluoro-2-methyl-1,3-benzothiaz...)
Affinity DataIC50:  0.782nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458384(1-[6-[(3R,5S)-1-[(6-fluoro-2-methyl-1,3-benzothiaz...)
Affinity DataIC50:  0.782nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM158179(US9029367, 3)
Affinity DataIC50:  6.66nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM158178(US9029367, 2)
Affinity DataIC50:  13.2nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM158177(US9029367, 1)
Affinity DataIC50:  15.6nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM158181(US9029367, 57)
Affinity DataIC50:  25.7nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM158180(US9029367, 34)
Affinity DataIC50:  45nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM126005(US8772282, 1 | US8772282, 203)
Affinity DataIC50:  64.4nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM126007(US8772282, 16)
Affinity DataIC50:  77.3nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM126012(US8772282, 32)
Affinity DataIC50:  91.2nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM126011(US8772282, 31)
Affinity DataIC50:  110nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM126010(US8772282, 30)
Affinity DataIC50:  166nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM126009(US8772282, 23)
Affinity DataIC50:  172nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent