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Found 51 with Last Name = 'winter' and Initial = 'hl'
TargetBeta-secretase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17786((4S)-4-(2-amino-6-phenoxy-3,4-dihydroquinazolin-3-...)
Affinity DataKi:  11nM ΔG°:  -45.0kJ/molepH: 5.0 T: 2°CAssay Description:BACE-1 activity was measured at pH 5 using the FS1 FRET substrate. Compounds were preincubated with recombinant BACE-1 for 20 min before adding subst...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17785(2-aminoquinazoline, 3 | 4-(2-amino-6-phenoxy-3,4-d...)
Affinity DataKi:  30nM ΔG°:  -42.5kJ/molepH: 5.0 T: 2°CAssay Description:BACE-1 activity was measured at pH 5 using the FS1 FRET substrate. Compounds were preincubated with recombinant BACE-1 for 20 min before adding subst...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17784(2-aminoquinazoline, 2 | 3-[(2-amino-6-phenoxy-3,4-...)
Affinity DataKi:  158nM ΔG°:  -38.4kJ/molepH: 5.0 T: 2°CAssay Description:BACE-1 activity was measured at pH 5 using the FS1 FRET substrate. Compounds were preincubated with recombinant BACE-1 for 20 min before adding subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17783(2-aminoquinazoline, 1 | 3-(2-amino-6-benzoyl-3,4-d...)
Affinity DataKi:  900nM ΔG°:  -34.2kJ/molepH: 5.0 T: 2°CAssay Description:BACE-1 activity was measured at pH 5 using the FS1 FRET substrate. Compounds were preincubated with recombinant BACE-1 for 20 min before adding subst...More data for this Ligand-Target Pair
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136661((R)-2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121279(2-Amino-1-[2-(5-ethyl-1H-imidazol-2-yl)-2,3-dihydr...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136662((S)-2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136644((S)-2-Amino-1-[(S)-5-chloro-2-(5-propyl-1H-imidazo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136648((S)-2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121284(2-Amino-1-[2-(5-methyl-1H-imidazol-2-yl)-2,3-dihyd...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121282((S)-1-((S)-2-aminobutanoyl)-N-butylindoline-2-carb...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136667(2-Amino-1-[(S)-5-chloro-2-(5-propyl-1H-imidazol-2-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136645((S)-2-Amino-1-[(S)-5-methoxy-2-(5-propyl-1H-imidaz...)
Affinity DataIC50:  16nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136654((S)-2-Amino-3-methyl-1-[(S)-2-(5-propyl-1H-imidazo...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121285((S)-2-Amino-1-[(S)-2-(5-ethyl-1H-imidazol-2-yl)-2,...)
Affinity DataIC50:  23nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121280(2-Amino-1-[2-(5-methyl-1H-imidazol-2-yl)-2,3-dihyd...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121283(2-Amino-1-[2-(1H-imidazol-2-yl)-2,3-dihydro-indol-...)
Affinity DataIC50:  36nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136663(2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2,3-d...)
Affinity DataIC50:  36nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136636(2-Amino-1-[(S)-5-fluoro-2-(5-propyl-1H-imidazol-2-...)
Affinity DataIC50:  46nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136666(2-Amino-1-[(S)-2-(5-butyl-1H-imidazol-2-yl)-2,3-di...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136656(2-Amino-1-[(S)-2-(4-methyl-5-propyl-1H-imidazol-2-...)
Affinity DataIC50:  55nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136660(2-Amino-1-[(S)-5-methoxy-2-(5-propyl-1H-imidazol-2...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17786((4S)-4-(2-amino-6-phenoxy-3,4-dihydroquinazolin-3-...)
Affinity DataIC50:  110nMpH: 4.0 T: 2°CAssay Description:Cathepsin D activity was measured at pH 4 using a FRET peptide substrate. Compounds were preincubated with recombinant human liver cathepsin D for 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136651(({2-[(S)-1-(2-Amino-acetyl)-2,3-dihydro-1H-indol-2...)
Affinity DataIC50:  135nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136652(2-Amino-1-[(S)-2-(5-ethyl-1H-imidazol-2-yl)-2,3-di...)
Affinity DataIC50:  194nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136650(2-[(S)-1-(2-Amino-acetyl)-2,3-dihydro-1H-indol-2-y...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136655(2-[(S)-1-(2-Amino-acetyl)-2,3-dihydro-1H-indol-2-y...)
Affinity DataIC50:  210nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136637(2-Amino-1-[(S)-2-(1H-benzoimidazol-2-yl)-2,3-dihyd...)
Affinity DataIC50:  450nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136638((S)-2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-3...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136638((S)-2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-3...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136668((S)-2-Amino-1-[(S)-2-(1H-benzoimidazol-2-yl)-2,3-d...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136658(CHEMBL138313 | [(S)-2-(5-Propyl-1H-imidazol-2-yl)-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136665(2-Amino-1-[(S)-2-(4-ethyl-1-methyl-1H-imidazol-2-y...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136635(2-Amino-1-[(S)-2-(5-propyl-[1,3,4]oxadiazol-2-yl)-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136647((S)-2-Amino-3-phenyl-1-[(S)-2-(5-propyl-1H-imidazo...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17786((4S)-4-(2-amino-6-phenoxy-3,4-dihydroquinazolin-3-...)
Affinity DataIC50:  2.70E+3nMpH: 7.4 T: 2°CAssay Description:Renin activity was measured at pH 7.4 using a FRET peptide substrate. Compounds were added to recombinant human rennin and mixed before substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136641(2-Amino-1-[(S)-2-(5-ethyl-thiazol-2-yl)-2,3-dihydr...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136669((1H-Imidazol-4-yl)-[(S)-2-(5-propyl-1H-imidazol-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136664(2-Amino-1-[(S)-2-(5-propyl-4H-[1,2,4]triazol-3-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121278(3-Ethyl-2,3,10,10a-tetrahydro-pyrazino[1,2-a]indol...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136657((2-Nitro-phenyl)-[(S)-2-(5-propyl-1H-imidazol-2-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136659(2-Amino-1-[(S)-2-(5-phenyl-1H-imidazol-2-yl)-2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121281(1-[2-(5-Propyl-1H-imidazol-2-yl)-2,3-dihydro-indol...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136649((3-Amino-phenyl)-[(S)-2-(5-propyl-1H-imidazol-2-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136646(2-Amino-1-[(S)-2-(5-ethyl-1-methyl-1H-imidazol-2-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136643((S)-2-[(S)-2-(5-Ethyl-1H-imidazol-2-yl)-2,3-dihydr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136642((S)-2-Methylamino-1-[(S)-2-(5-propyl-1H-imidazol-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136640((2-Amino-phenyl)-[(S)-2-(5-propyl-1H-imidazol-2-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136639(3-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2,3-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121285((S)-2-Amino-1-[(S)-2-(5-ethyl-1H-imidazol-2-yl)-2,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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