TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 430nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 540nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of LAR (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectrophot...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.70E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 2.60E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 2.70E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 3.70E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 3.90E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 3.90E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 4.70E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 4.80E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectrop...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 5.60E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 5.90E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectroph...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 6.20E+3nMAssay Description:Inhibition of LMW-PTP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectro...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 6.80E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
Affinity DataKi: 6.90E+3nMAssay Description:Inhibition of MKP5 (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 9.60E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.40E+4nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.50E+4nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of N-terminal GST tagged recombinant human FGFR2 (400 to 821 residues) expressed in an Sf9 infected baculovirus expression system using bi...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of N-terminal GST tagged recombinant human FGFR2 (400 to 821 residues) expressed in an Sf9 infected baculovirus expression system using bi...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human FGFR1 using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system usin...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system usin...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of N-terminal GST tagged recombinant human FGFR2 (400 to 821 residues) expressed in an Sf9 infected baculovirus expression system using bi...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system usin...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system usin...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system usin...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system usin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human FGFR3 V555M mutant using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins followed by substrat...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system usin...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human FGFR1 using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system usin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.980nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system usin...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal GST tagged recombinant human FGFR2 (400 to 821 residues) expressed in an Sf9 infected baculovirus expression system using bi...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system usin...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of GST-tagged human recombinant ALK2 (145 to 509 residues) expressed in baculovirus expression system using casein as substrate in presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system usin...More data for this Ligand-Target Pair