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Found 323 with Last Name = 'wong' and Initial = 'jc'
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM120996(US8716285, 53)
Affinity DataIC50:  12nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50078748(CHEMBL3415629)
Affinity DataIC50:  17nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50078747(CHEMBL3415628)
Affinity DataIC50:  18nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50078695(CHEMBL3415627)
Affinity DataIC50:  21nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50497300(CHEMBL3335461)
Affinity DataIC50:  25nMAssay Description:Inhibition of YAP/ GST-TEAD1 (unknown origin) interaction by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50:  30nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50027661(CHEMBL3338417)
Affinity DataIC50:  40nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50497290(CHEMBL3335458)
Affinity DataIC50:  41nMAssay Description:Inhibition of YAP/ GST-TEAD1 (unknown origin) interaction by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50497304(CHEMBL3335453)
Affinity DataIC50:  42nMAssay Description:Inhibition of YAP/ GST-TEAD1 (unknown origin) interaction by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50027662(CHEMBL3338418)
Affinity DataIC50:  48nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50334368(CHEMBL1643325 | N-(2-aminophenyl)-3-(4-(2-(4'-cycl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50:  50nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50027662(CHEMBL3338418)
Affinity DataIC50:  50nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  54nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 1(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50334366(CHEMBL1643308 | N-(2-aminophenyl)-3-(4-(1-(2-morph...)
Affinity DataIC50:  60nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399006(CHEMBL2177587)
Affinity DataIC50:  60nMAssay Description:Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50334366(CHEMBL1643308 | N-(2-aminophenyl)-3-(4-(1-(2-morph...)
Affinity DataIC50:  60nMAssay Description:Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50078687(CHEMBL3415619)
Affinity DataIC50:  63nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50497306(CHEMBL3335463)
Affinity DataIC50:  75nMAssay Description:Inhibition of YAP/ GST-TEAD1 (unknown origin) interaction by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50078747(CHEMBL3415628)
Affinity DataIC50:  76nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027662(CHEMBL3338418)
Affinity DataIC50:  80nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027662(CHEMBL3338418)
Affinity DataIC50:  80nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50078680(CHEMBL3415454)
Affinity DataIC50:  90nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  100nMAssay Description:Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50078690(CHEMBL3415621)
Affinity DataIC50:  100nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50078682(CHEMBL3415618)
Affinity DataIC50:  110nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50078689(CHEMBL3415620)
Affinity DataIC50:  120nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50078757(CHEMBL3415453)
Affinity DataIC50:  120nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  130nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50078689(CHEMBL3415620)
Affinity DataIC50:  140nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399005(CHEMBL2177588)
Affinity DataIC50:  140nMAssay Description:Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50497296(CHEMBL3335452)
Affinity DataIC50:  150nMAssay Description:Inhibition of YAP/ GST-TEAD1 (unknown origin) interaction by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50078681(CHEMBL3415456)
Affinity DataIC50:  150nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50078687(CHEMBL3415619)
Affinity DataIC50:  160nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50078757(CHEMBL3415453)
Affinity DataIC50:  160nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50078690(CHEMBL3415621)
Affinity DataIC50:  160nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM120985(US8716285, 42)
Affinity DataIC50:  160nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50078680(CHEMBL3415454)
Affinity DataIC50:  180nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50078748(CHEMBL3415629)
Affinity DataIC50:  180nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM120989(US8716285, 46)
Affinity DataIC50:  190nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50334367(CHEMBL1643315 | N-(2-aminophenyl)-3-(4-(2-oxo-1-(2...)
Affinity DataIC50:  200nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  200nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 11(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  200nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50399005(CHEMBL2177588)
Affinity DataIC50:  200nMAssay Description:Inhibition of HDAC3 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM120987(US8716285, 44)
Affinity DataIC50:  210nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50078750(CHEMBL3415446)
Affinity DataIC50:  210nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  220nMAssay Description:Inhibition of HDAC2 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50399006(CHEMBL2177587)
Affinity DataIC50:  230nMAssay Description:Inhibition of HDAC3 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50399004(CHEMBL2177582)
Affinity DataIC50:  230nMAssay Description:Inhibition of HDAC3 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50078756(CHEMBL3415452)
Affinity DataIC50:  240nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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