Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of YAP/ GST-TEAD1 (unknown origin) interaction by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of YAP/ GST-TEAD1 (unknown origin) interaction by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of YAP/ GST-TEAD1 (unknown origin) interaction by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of YAP/ GST-TEAD1 (unknown origin) interaction by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of YAP/ GST-TEAD1 (unknown origin) interaction by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC3 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of HDAC2 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of HDAC3 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of HDAC3 using p53 (379 to 382 residues) based fluorogenic peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair