Compile Data Set for Download or QSAR
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Found 78 with Last Name = 'wong' and Initial = 'ky'
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
The Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50548231(CHEMBL4753599)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of wild type N-terminal His6-tagged Klebsiella pneumoniae NDM-1 expressed in Escherichia coli BL21 assessed as inhibition constant using n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585812(CHEMBL5091943)
Affinity DataIC50:  122nMAssay Description:Displacement of fluorescent labeled derivative from recombinant human hepatic glucokinase incubated for 30 mins in presence of 12 mM glucose by fluor...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataIC50:  123nMAssay Description:Displacement of fluorescent labeled derivative from recombinant human hepatic glucokinase incubated for 30 mins in presence of 12 mM glucose by fluor...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50264501(CHEMBL253715 | CHEMBL484670 | N-(5-N-Methyl-10H-in...)
Affinity DataIC50:  160nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50264595(CHEMBL491633 | N-(7-Fluoro-5-N-methyl-10H-indolo[3...)
Affinity DataIC50:  200nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50264499(CHEMBL253508 | CHEMBL507633 | N-(5-N-Methyl-10H-in...)
Affinity DataIC50:  220nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50264635(CHEMBL490013 | N-(7,9-Difluoro-5-N-methyl-10H-indo...)
Affinity DataIC50:  270nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50264593(11-(3-(dimethylamino)propylamino)-7-fluoro-5-methy...)
Affinity DataIC50:  310nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50264535(CHEMBL482414 | N-(5-N-Methyl-benzofuro[3,2-b]quino...)
Affinity DataIC50:  370nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50264633(CHEMBL489811 | N-(7,9-Difluoro-5-N-methyl-10H-indo...)
Affinity DataIC50:  400nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50176906(CHEMBL219728 | N'-(10H-indolo[3,2-b]quinolin-11-yl...)
Affinity DataIC50:  630nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
The Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50548232(CHEMBL4758313)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Klebsiella pneumoniae NDM-1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
The Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50548231(CHEMBL4753599)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of wild type N-terminal His6-tagged Klebsiella pneumoniae NDM-1 expressed in Escherichia coli BL21 using nitrocefin as substrate measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585829(CHEMBL5092846)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585830(CHEMBL5072442)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585823(CHEMBL5081517)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585812(CHEMBL5091943)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of P-gp transporter (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585814(CHEMBL5071861)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585816(CHEMBL5086985)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585817(CHEMBL5075882)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585818(CHEMBL5080889)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585819(CHEMBL5088988)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585820(CHEMBL5093208)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585821(CHEMBL5093978)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585822(CHEMBL5083369)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585824(CHEMBL5084870)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585825(CHEMBL5086686)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585826(CHEMBL5085491)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585827(CHEMBL5088522)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585831(CHEMBL5076377)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585832(CHEMBL5087489)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585833(CHEMBL5094606)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585834(CHEMBL5077438)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585835(CHEMBL5079866)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585836(CHEMBL5082691)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585837(CHEMBL5080166)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585821(CHEMBL5093978)
Affinity DataEC50:  48nMAssay Description:Activation of recombinant full length human liver glucokinase expressed in Escherichia coli incubated for 10 mins by plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
The Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50589185(CHEMBL5199894)
Affinity DataKd:  600nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHexokinase-4(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585823(CHEMBL5081517)
Affinity DataEC50:  76nMAssay Description:Activation of recombinant full length human liver glucokinase expressed in Escherichia coli incubated for 10 mins by plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585824(CHEMBL5084870)
Affinity DataEC50:  24nMAssay Description:Activation of recombinant full length human liver glucokinase expressed in Escherichia coli incubated for 10 mins by plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585825(CHEMBL5086686)
Affinity DataEC50:  530nMAssay Description:Activation of recombinant full length human liver glucokinase expressed in Escherichia coli incubated for 10 mins by plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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