TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
The Hong Kong Polytechnic University
Curated by ChEMBL
The Hong Kong Polytechnic University
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Inhibition of wild type N-terminal His6-tagged Klebsiella pneumoniae NDM-1 expressed in Escherichia coli BL21 assessed as inhibition constant using n...More data for this Ligand-Target Pair
Affinity DataIC50: 122nMAssay Description:Displacement of fluorescent labeled derivative from recombinant human hepatic glucokinase incubated for 30 mins in presence of 12 mM glucose by fluor...More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Displacement of fluorescent labeled derivative from recombinant human hepatic glucokinase incubated for 30 mins in presence of 12 mM glucose by fluor...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
The Hong Kong Polytechnic University
Curated by ChEMBL
The Hong Kong Polytechnic University
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Klebsiella pneumoniae NDM-1More data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
The Hong Kong Polytechnic University
Curated by ChEMBL
The Hong Kong Polytechnic University
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of wild type N-terminal His6-tagged Klebsiella pneumoniae NDM-1 expressed in Escherichia coli BL21 using nitrocefin as substrate measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of P-gp transporter (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERG by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataEC50: 48nMAssay Description:Activation of recombinant full length human liver glucokinase expressed in Escherichia coli incubated for 10 mins by plate reader analysisMore data for this Ligand-Target Pair
TargetCell division protein FtsZ(Staphylococcus aureus)
The Hong Kong Polytechnic University
Curated by ChEMBL
The Hong Kong Polytechnic University
Curated by ChEMBL
Affinity DataKd: 600nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataEC50: 76nMAssay Description:Activation of recombinant full length human liver glucokinase expressed in Escherichia coli incubated for 10 mins by plate reader analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Activation of recombinant full length human liver glucokinase expressed in Escherichia coli incubated for 10 mins by plate reader analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 530nMAssay Description:Activation of recombinant full length human liver glucokinase expressed in Escherichia coli incubated for 10 mins by plate reader analysisMore data for this Ligand-Target Pair