BindingDB PrimarySearch_ki

Found 101 with Last Name = 'wu' and Initial = 'cs'

Replicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology

PNG

BDBM11233(N-[(benzyloxy)carbonyl]-O-(tert-butyl)-L-threonyl-...)

Ki: 53nM ΔG°: -41.5kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair

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Replicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology

PNG

BDBM11232(N-[(benzyloxy)carbonyl]-O-(tert-butyl)-L-threonyl-...)

Ki: 58nM ΔG°: -41.3kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair

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Replicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology

PNG

BDBM11231(N-[(benzyloxy)carbonyl]-L-valyl-N1-((1S,2E)-4-etho...)

Ki: 660nM ΔG°: -35.3kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair

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Replicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology

PNG

BDBM11230(AG7088 analogue 2d | CHEMBL277716 | N-[(benzyloxy)...)

Ki: 2.26E+3nM ΔG°: -32.2kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair

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Replicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology

PNG

BDBM11229(AG7088 analogue 2a | CHEMBL20636 | N-[(5-methyliso...)

Ki: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579499(CHEMBL4847875)

IC50: 0.530nMAssay Description:Inhibition of wild-type human partial length CSF1R (I564 to S939 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579499(CHEMBL4847875)

IC50: 1.10nMAssay Description:Inhibition of human c-Kit by Kinomescan methodMore data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579496(CHEMBL4851545)

IC50: 1.40nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579463(CHEMBL4851635)

IC50: 8.30nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Aurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579464(CHEMBL4867079)

IC50: 9nMAssay Description:Inhibition of recombinant GST-AURKA (residues Ser123 to Ser401) (unknown origin) expressed in Sf9 insect cells using tetra(-LRRASLG) peptide as subst...More data for this Ligand-Target Pair

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Aurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579465(CHEMBL4861838)

IC50: 9nMAssay Description:Inhibition of recombinant GST-AURKA (residues Ser123 to Ser401) (unknown origin) expressed in Sf9 insect cells using tetra(-LRRASLG) peptide as subst...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579464(CHEMBL4867079)

IC50: >10nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579474(CHEMBL4850463)

IC50: >10nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579483(CHEMBL4877148)

IC50: 11nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579494(CHEMBL4846384)

IC50: 11nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579476(CHEMBL4860468)

IC50: 11nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579479(CHEMBL4857271)

IC50: 12nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Aurora kinase B(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579500(CHEMBL4864729)

IC50: 13nMAssay Description:Inhibition of human recombinant full length GST-AURKB using tetra(-LRRASLG) peptide as substrate incubated for 20 mins by ATP Kinase Glo assayMore data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579495(CHEMBL4870360)

IC50: 13nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579490(CHEMBL4870448)

IC50: 13nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579499(CHEMBL4847875)

IC50: 14nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579480(CHEMBL4877440)

IC50: 14nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579486(CHEMBL4849425)

IC50: 15nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579475(CHEMBL4864248)

IC50: 15nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579487(CHEMBL4857690)

IC50: 16nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579485(CHEMBL4873828)

IC50: 16nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579500(CHEMBL4864729)

IC50: 19nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579492(CHEMBL4866196)

IC50: 19nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579462(CHEMBL4877247)

IC50: 21nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Aurora kinase B(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579480(CHEMBL4877440)

IC50: 22nMAssay Description:Inhibition of human recombinant full length GST-AURKB using tetra(-LRRASLG) peptide as substrate incubated for 20 mins by ATP Kinase Glo assayMore data for this Ligand-Target Pair

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Aurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579500(CHEMBL4864729)

IC50: 22nMAssay Description:Inhibition of recombinant GST-AURKA (residues Ser123 to Ser401) (unknown origin) expressed in Sf9 insect cells using tetra(-LRRASLG) peptide as subst...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579497(CHEMBL4863584)

IC50: 24nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50340929(1-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-ph...)

IC50: 30nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50355494(CHEMBL1908396)

IC50: 30nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579478(CHEMBL4857617)

IC50: 30nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Platelet-derived growth factor receptor beta(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579499(CHEMBL4847875)

IC50: 32nMAssay Description:Inhibition of wild-type human partial length PDGFRbeta (V582 to Y1009 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)

IC50: 35nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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3D Structure (crystal)

Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579484(CHEMBL4859405)

IC50: 36nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Tunghai University

Curated by ChEMBL

PNG

BDBM50075319(2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHY...)

IC50: 40nMAssay Description:Inhibition of pig liver 4-Hydroxyphenylpyruvate dioxygenase (4-HPPD) enzymeMore data for this Ligand-Target Pair

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4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Tunghai University

Curated by ChEMBL

PNG

BDBM50088804(1,3-Cyclohexanedione, 2-(2-nitro-4-(trifluoromethy...)

IC50: 40nMAssay Description:Inhibition of 4-hydroxyphenylpyruvate dioxygenase of purified pig liver by enol-borate methodMore data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579473(CHEMBL4876562)

IC50: 41nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579470(CHEMBL4877828)

IC50: 44nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579488(CHEMBL4846051)

IC50: 50nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Platelet-derived growth factor receptor alpha(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579499(CHEMBL4847875)

IC50: 53nMAssay Description:Inhibition of wild-type human partial length PDGFRalpha (V575 to D1002 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579469(CHEMBL4851294)

IC50: 58nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Epithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579499(CHEMBL4847875)

IC50: 60nMAssay Description:Inhibition of wild-type human partial length DDR1 (R565 to V876 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579472(CHEMBL4871989)

IC50: 63nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579482(CHEMBL4874053)

IC50: 64nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579499(CHEMBL4847875)

IC50: 64nMAssay Description:Inhibition of wild-type human partial length FLT3 (V592 to Y969 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

PNG

BDBM50579481(CHEMBL4878431)

IC50: 64nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair

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Displayed 1 to 50 (of 101 total ) | Next | Last >>

Filter my 101 hits

Targets 12▿
- Macrophage colony-stimulating factor 1 receptor 43
- 4-hydroxyphenylpyruvate dioxygenase 35
- Aurora kinase A 6
- Replicase polyprotein 1ab 5
- Aurora kinase B 5
- Receptor-type tyrosine-protein kinase FLT3 1
- Mast/stem cell growth factor receptor Kit 1
- Platelet-derived growth factor receptor beta 1
- Epithelial discoidin domain-containing receptor 1 1
- Vascular endothelial growth factor receptor 2 1
- Platelet-derived growth factor receptor alpha 1
- Serine/threonine-protein kinase PAK 3 1
Publications 5▿
- J Med Chem 64: 14477-14497 (2021) 61
- Bioorg Med Chem Lett 10: 843-5 (2000) 14
- Bioorg Med Chem Lett 12: 1709-13 (2002) 11
- J Med Chem 45: 2222-8 (2002) 10
- J Med Chem 49: 4971-80 (2006) 5
Institutions 4▿
- National Health Research Institutes 61
- Tunghai University 21
- Tunghai Christian University 14
- Taigen Biotechnology 5
Affinity: 0.53 to 9.0E+5 nM▿
- Ki 5
- IC50 96
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 14