TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology
Taigen Biotechnology
Affinity DataKi: 53nM ΔG°: -41.5kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology
Taigen Biotechnology
Affinity DataKi: 58nM ΔG°: -41.3kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology
Taigen Biotechnology
Affinity DataKi: 660nM ΔG°: -35.3kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology
Taigen Biotechnology
Affinity DataKi: 2.26E+3nM ΔG°: -32.2kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology
Taigen Biotechnology
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 102nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 127nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 199nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 219nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 315nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 343nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 372nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 418nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 463nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human IDO1 expressed in Escherichia coli BL21(DE3) using D-tryptophan as substrate assessed as formation of kynurenine productionMore data for this Ligand-Target Pair
Affinity DataIC50: 537nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 629nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 633nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 743nMAssay Description:Inhibition of human HDAC1 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 835nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 884nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 891nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of human HDAC2 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by caliper as...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human HDAC11 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.63E+3nMAssay Description:Inhibition of human HDAC4 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.12E+3nMAssay Description:Inhibition of human HDAC8 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.63E+3nMAssay Description:Inhibition of human HDAC10 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Affinity DataKd: 290nMAssay Description:Binding affinity to IDO1 (unknown origin) assessed as dissociation constant by AR2G sensor based assayMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Affinity DataKd: 1.10E+3nMAssay Description:Binding affinity to IDO1 (unknown origin) assessed as dissociation constant by bio-layer interferometry assayMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Affinity DataKd: 640nMAssay Description:Binding affinity to IDO1 (unknown origin) assessed as dissociation constant by bio-layer interferometry assayMore data for this Ligand-Target Pair