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Found 39 with Last Name = 'wyrwa' and Initial = 'r'
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080528(3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition constant(Ki) for inhibition of PPIase activity of human FK506 binding protein 12 (Conc=14 nM) of FKBPsfamilyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP4(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080528(3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...)
Affinity DataKi:  2.42E+4nMAssay Description:Inhibition constant(Ki) for inhibition of PPIase activity of rabbit FK506 binding protein 52 (Conc=52 nM) of FKBPsfamilyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP14(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080528(3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...)
Affinity DataKi:  7.62E+4nMAssay Description:Inhibition constant(Ki) for inhibition of PPIase activity of Photobacterium sp. FK506 binding protein 22 (Conc=41 nM) of FKBPsfamilyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP3(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080528(3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...)
Affinity DataKi:  1.24E+5nMAssay Description:Inhibition constant(Ki) for inhibition of PPIase activity of L. pneumophilia FK506 binding protein 25 (Conc=40 nM) of FKBPsfamilyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 4(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080528(3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...)
Affinity DataKi:  1.87E+5nMAssay Description:Inhibition constant(Ki) for inhibition of PPIase activity of E. coli parvulin (Conc=4 nM) of Parvulins sfamilyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080528(3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition constant(Ki) for inhibition of PPIase activity of human Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Conc=4 nM) of Parvulins fa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261565(CHEMBL4098239)
Affinity DataIC50:  7nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261578(CHEMBL4085932)
Affinity DataIC50:  65nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261559(CHEMBL4067116)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261561(CHEMBL4075710)
Affinity DataIC50:  110nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261577(CHEMBL4077445)
Affinity DataIC50:  120nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261563(CHEMBL4089618)
Affinity DataIC50:  129nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261562(CHEMBL4068479)
Affinity DataIC50:  198nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261581(CHEMBL4086863)
Affinity DataIC50:  202nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261575(CHEMBL4102621)
Affinity DataIC50:  210nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261580(CHEMBL4100191)
Affinity DataIC50:  232nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261583(CHEMBL4081744)
Affinity DataIC50:  250nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261579(CHEMBL4064401)
Affinity DataIC50:  250nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261570(CHEMBL4071193)
Affinity DataIC50:  250nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261585(CHEMBL4073866)
Affinity DataIC50:  290nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261582(CHEMBL4083620)
Affinity DataIC50:  300nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataIC50:  309nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261560(CHEMBL4094577)
Affinity DataIC50:  325nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261564(CHEMBL4059816)
Affinity DataIC50:  500nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080528(3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...)
Affinity DataIC50:  3.60E+3nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080534(CHEMBL333448 | ethyl (4-{(2R)-2-[(1S,3S,5S)-3,5-di...)
Affinity DataIC50:  4.40E+3nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261573(CHEMBL4098852)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261584(CHEMBL4062557)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261576(CHEMBL4078353)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080531(2-{4-[(R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxo-cyclohe...)
Affinity DataIC50:  2.16E+4nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080530(4-{4-[(R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxo-cyclohe...)
Affinity DataIC50:  2.23E+4nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080532(4-{4-[(R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxo-cyclohe...)
Affinity DataIC50:  6.82E+4nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080535(1-Benzyl-4-[(R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxo-c...)
Affinity DataIC50:  1.17E+5nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080527(4-[(R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxo-cyclohexyl...)
Affinity DataIC50:  1.24E+5nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080536(4-((R)-2-Hydroxy-2-{(1R,3S,5S)-2-[(Z)-hydroxyimino...)
Affinity DataIC50:  1.77E+5nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080533(CHEMBL331865 | {4-[(R)-2-(Adamantan-1-ylcarbamoylo...)
Affinity DataIC50: >2.00E+5nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080529(Acetic acid (R)-1-((1S,3S,5S)-3,5-dimethyl-2-oxo-c...)
Affinity DataIC50: >2.00E+5nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataEC50:  2.30nMAssay Description:Binding affinity to ER (unknown origin) expressed in UAS-bla GripTite 293 cells by Select screen competitive binding assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261561(CHEMBL4075710)
Affinity DataEC50:  432nMAssay Description:Binding affinity to ER (unknown origin) expressed in UAS-bla GripTite 293 cells by Select screen competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed