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Found 23 with Last Name = 'zemlicka' and Initial = 'j'
TargetPhosphotransferase pUL97(Human cytomegalovirus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50330328((Z)-2-amino-9-((2,2-bis(hydroxymethyl)cyclopropyli...)
Affinity DataKi:  3nMAssay Description:Inhibition of Human cytomegalovirus pUL97 assessed as inhibition of phosphorylation of 100 to 1000 uM cyclopropavirMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50134782(6-amino-9-[(Z)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...)
Affinity DataKi:  320nMAssay Description:Inhibitory activity against HIV-1 Reverse transcriptase wild-type (RT wt)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50164644(2',3'-Dideoxyadenosine Triphosphate (Ddatp) | 2',3...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (RT M184V)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50164644(2',3'-Dideoxyadenosine Triphosphate (Ddatp) | 2',3...)
Affinity DataKi:  510nMAssay Description:Inhibitory activity against HIV-1 Reverse transcriptase wild-type (RT wt)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50164644(2',3'-Dideoxyadenosine Triphosphate (Ddatp) | 2',3...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (RT M184I)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50134782(6-amino-9-[(Z)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (RT M184V)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50134782(6-amino-9-[(Z)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (RT M184I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50134783(6-amino-9-[(E)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibitory activity against HIV-1 Reverse transcriptase wild-type (RT wt)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50134783(6-amino-9-[(E)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...)
Affinity DataKi:  5.20E+4nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (RT M184V)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50134783(6-amino-9-[(E)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...)
Affinity DataKi:  7.10E+4nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (RT M184I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50002692((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50002692((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataIC50:  17nMAssay Description:Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50061986(CHEMBL305612 | [2-(6-Amino-purin-9-ylmethylene)-cy...)
Affinity DataIC50:  800nMAssay Description:Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50061987(2-Amino-9-[2-hydroxymethyl-cycloprop-(Z)-ylideneme...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50061983(2-Amino-9-[2-hydroxymethyl-cycloprop-(E)-ylideneme...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50061984(CHEMBL74478 | {(2E)-2-[(6-amino-9H-purin-9-yl)meth...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50061986(CHEMBL305612 | [2-(6-Amino-purin-9-ylmethylene)-cy...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50061987(2-Amino-9-[2-hydroxymethyl-cycloprop-(Z)-ylideneme...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50061983(2-Amino-9-[2-hydroxymethyl-cycloprop-(E)-ylideneme...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50061985(CHEMBL76121 | {2-[1-(2-Amino-6-chloro-purin-9-yl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50061982(CHEMBL75950 | {2-[1-(2-Amino-6-chloro-purin-7-yl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50061984(CHEMBL74478 | {(2E)-2-[(6-amino-9H-purin-9-yl)meth...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50059015(CHEMBL69158 | [(E)-5-(6-Amino-purin-9-yl)-pent-3-e...)
Affinity DataEC50:  9.00E+3nMAssay Description:tested for its inhibition of HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed