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Found 106 with Last Name = 'van straten' and Initial = 'n'
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataKi:  25.1nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14031(5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinoli...)
Affinity DataKi:  31.6nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417674(CHEMBL1643361)
Affinity DataKi:  63.1nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataKi:  100nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)
Affinity DataKi:  794nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417674(CHEMBL1643361)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14031(5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinoli...)
Affinity DataKi:  7.94E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417668(CHEMBL1643368)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataKi:  2.51E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataKi:  7.94E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410307(CHEMBL360981)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410306(CHEMBL436481)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410303(CHEMBL361847)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410309(CHEMBL365545)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50162936(Biphenyl-4-carboxylic acid (1-acetyl-2,2,4-trimeth...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of maximum response evoked by cAMP on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410304(CHEMBL195469)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410302(CHEMBL361167)
Affinity DataIC50:  27nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50162936(Biphenyl-4-carboxylic acid (1-acetyl-2,2,4-trimeth...)
Affinity DataIC50:  28nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50162936(Biphenyl-4-carboxylic acid (1-acetyl-2,2,4-trimeth...)
Affinity DataIC50:  28nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410308(CHEMBL192868)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410298(CHEMBL178980)
Affinity DataIC50:  31nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410294(CHEMBL195347)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410292(CHEMBL192334)
Affinity DataIC50:  54nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410300(CHEMBL179505)
Affinity DataIC50:  76nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410297(CHEMBL372649)
Affinity DataIC50:  166nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410299(CHEMBL426824)
Affinity DataIC50:  170nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417683(CHEMBL1643573)
Affinity DataIC50:  240nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)
Affinity DataIC50:  240nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410296(CHEMBL363164)
Affinity DataIC50:  240nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataIC50:  245nMAssay Description:Inhibition of ROCK-2 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417687(CHEMBL1643356)
Affinity DataIC50:  427nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Rattus norvegicus)
Research And Development

Curated by ChEMBL
LigandPNGBDBM50162936(Biphenyl-4-carboxylic acid (1-acetyl-2,2,4-trimeth...)
Affinity DataIC50:  540nMAssay Description:In vitro inhibition against maximum response evoked by cAMP in rat GFSHR-17 granulosa cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417678(CHEMBL1643365)
Affinity DataIC50:  575nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14031(5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinoli...)
Affinity DataIC50:  575nMAssay Description:Inhibition of ROCK-2 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410301(CHEMBL372506)
Affinity DataIC50:  580nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417670(CHEMBL1643357)
Affinity DataIC50:  589nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14031(5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinoli...)
Affinity DataIC50:  759nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417671(CHEMBL1643358)
Affinity DataIC50:  776nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417672(CHEMBL1643359)
Affinity DataIC50:  813nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataIC50:  871nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410291(CHEMBL194996)
Affinity DataIC50:  930nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417673(CHEMBL1643360)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417674(CHEMBL1643361)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417674(CHEMBL1643361)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of ROCK-2 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of ROCK-2 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417675(CHEMBL1643362)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417676(CHEMBL1643363)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417677(CHEMBL1643364)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50410293(CHEMBL195321)
Affinity DataIC50:  1.88E+3nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417681(CHEMBL1643571)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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