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Found 46 with Last Name = 'van der haas' and Initial = 'rn'
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50325534(CHEMBL267495 | nalfurafine)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50000780(2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130756(CHEMBL3634515)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130756(CHEMBL3634515)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50027433(CHEMBL603370 | GR-89696)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50325534(CHEMBL267495 | nalfurafine)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]-DPDPE from delta opioid receptor in rat brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50325534(CHEMBL267495 | nalfurafine)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-DPDPE from delta opioid receptor in rat brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-DPDPE from delta opioid receptor in rat brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50021992(CHEMBL3299005)
Affinity DataKi:  9.40nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50021992(CHEMBL3299005)
Affinity DataKi:  9.70nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50021992(CHEMBL3299005)
Affinity DataKi:  9.70nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130755(CHEMBL3634398)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130758(CHEMBL3634395)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130753(CHEMBL3634396)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-DPDPE from delta opioid receptor in rat brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130756(CHEMBL3634515)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]-DPDPE from delta opioid receptor in rat brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130756(CHEMBL3634515)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]-DPDPE from delta opioid receptor in rat brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130756(CHEMBL3634515)
Affinity DataKi:  113nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130756(CHEMBL3634515)
Affinity DataKi:  113nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130754(CHEMBL3634397)
Affinity DataKi:  115nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130755(CHEMBL3634398)
Affinity DataKi:  118nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130755(CHEMBL3634398)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]-DPDPE from delta opioid receptor in rat brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50325534(CHEMBL267495 | nalfurafine)
Affinity DataKi:  170nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130758(CHEMBL3634395)
Affinity DataKi:  309nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50000780(2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  340nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130754(CHEMBL3634397)
Affinity DataKi:  343nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50027433(CHEMBL603370 | GR-89696)
Affinity DataKi:  360nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50021992(CHEMBL3299005)
Affinity DataKi:  497nMAssay Description:Displacement of [3H]-DPDPE from delta opioid receptor in rat brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130758(CHEMBL3634395)
Affinity DataKi:  520nMAssay Description:Displacement of [3H]-DPDPE from delta opioid receptor in rat brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130754(CHEMBL3634397)
Affinity DataKi:  1.02E+3nMAssay Description:Displacement of [3H]-DPDPE from delta opioid receptor in rat brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130753(CHEMBL3634396)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130756(CHEMBL3634515)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at kappa opioid receptor in human HEK293 cells after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130756(CHEMBL3634515)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at kappa opioid receptor in human HEK293 cells after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130758(CHEMBL3634395)
Affinity DataEC50:  125nMAssay Description:Agonist activity at kappa opioid receptor in human HEK293 cells after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50021992(CHEMBL3299005)
Affinity DataEC50:  110nMAssay Description:Agonist activity at kappa opioid receptor in human HEK293 cells after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50021992(CHEMBL3299005)
Affinity DataEC50:  110nMAssay Description:Agonist activity at kappa opioid receptor in human HEK293 cells after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50325534(CHEMBL267495 | nalfurafine)
Affinity DataEC50:  0.0340nMAssay Description:Agonist activity at kappa opioid receptor in human HEK293 cells after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataEC50:  2nMAssay Description:Agonist activity at kappa opioid receptor in human HEK293 cells after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130753(CHEMBL3634396)
Affinity DataEC50:  351nMAssay Description:Agonist activity at kappa opioid receptor in human HEK293 cells after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed