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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309549(3-(5-Fluoro-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...)
Affinity DataIC50:  66nMAssay Description:Inhibition of VEGFR3 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309549(3-(5-Fluoro-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...)
Affinity DataIC50:  82nMAssay Description:Inhibition of VEGFR2 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309549(3-(5-Fluoro-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...)
Affinity DataIC50:  150nMAssay Description:Inhibition of VEGFR1 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309549(3-(5-Fluoro-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...)
Affinity DataIC50:  182nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309549(3-(5-Fluoro-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of TIE2 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309549(3-(5-Fluoro-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of PDGFRalpha after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309549(3-(5-Fluoro-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...)
Affinity DataIC50:  2.67E+3nMAssay Description:Inhibition of PDGFRbeta after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309549(3-(5-Fluoro-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...)
Affinity DataIC50:  3.47E+3nMAssay Description:Inhibition of KIT after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309549(3-(5-Fluoro-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...)
Affinity DataIC50: >8.48E+3nMAssay Description:Inhibition of ERBB2 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309549(3-(5-Fluoro-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...)
Affinity DataIC50: >8.48E+3nMAssay Description:Inhibition of EGFR after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309549(3-(5-Fluoro-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...)
Affinity DataIC50:  8.53E+3nMAssay Description:Inhibition of IGF1R after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed