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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Phosphatidylinositol 3-kinase catalytic subunit type 3
(Homo sapiens (Human))
Neuropore Therapies
US Patent
Ligand
BDBM535712
(5-(6-morpholino-4- (phenylsulfonyl)pyridin-2-yl)-4...)
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Affinity Data
IC50: 287nM
Assay Description:
The substrate (Phosphatidylinositol (PI): Phosphatidylserine (PS)) was added to freshly prepared reaction buffer (40 mM Tris-HCl (pH7.5), 3 μM O...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Neuropore Therapies
US Patent
Ligand
BDBM535712
(5-(6-morpholino-4- (phenylsulfonyl)pyridin-2-yl)-4...)
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Copy InChI
Affinity Data
IC50: 5.24E+3nM
Assay Description:
Compounds were prepared at 100× final concentration using a 12-point, 1:3 serial-dilution in DMSO, with DMSO control as the 12th point. Compound was ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI