Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetInsulin-like growth factor 1 receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296348(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)
Affinity DataIC50:  86nMAssay Description:Inhibition of IGF1R by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Mouse)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296348(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)
Affinity DataIC50:  140nMAssay Description:Inhibition of insulin receptor-mediated proliferation of mouse NIH/3T3 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Mouse)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296348(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)
Affinity DataIC50:  150nMAssay Description:Inhibition of IGF1R-mediated proliferation of mouse NIH/3T3 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296348(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of insulin receptor by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296348(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of c-KITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296348(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HER1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296348(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BCR-ABL p210More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed