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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Insulin-like growth factor 1 receptor
(Human)
University of South Florida
Curated by
ChEMBL
Ligand
BDBM50296348
(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)
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Affinity Data
IC50: 86nM
Assay Description:
Inhibition of IGF1R by cell based assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Insulin receptor
(Mouse)
University of South Florida
Curated by
ChEMBL
Ligand
BDBM50296348
(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)
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Affinity Data
IC50: 140nM
Assay Description:
Inhibition of insulin receptor-mediated proliferation of mouse NIH/3T3 cells after 48 hrs by MTT assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Mouse)
University of South Florida
Curated by
ChEMBL
Ligand
BDBM50296348
(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 150nM
Assay Description:
Inhibition of IGF1R-mediated proliferation of mouse NIH/3T3 cells after 48 hrs by MTT assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin receptor
(Human)
University of South Florida
Curated by
ChEMBL
Ligand
BDBM50296348
(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)
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Copy InChI
Affinity Data
IC50: 2.30E+3nM
Assay Description:
Inhibition of insulin receptor by cell based assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Human)
University of South Florida
Curated by
ChEMBL
Ligand
BDBM50296348
(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of c-KIT
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Human)
University of South Florida
Curated by
ChEMBL
Ligand
BDBM50296348
(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of HER1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Breakpoint cluster region protein/Tyrosine-protein kinase ABL1
(Human)
University of South Florida
Curated by
ChEMBL
Ligand
BDBM50296348
(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of BCR-ABL p210
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI