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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Beta-lactamase
(Escherichia coli)
Northwestern University Medical School
Curated by
ChEMBL
Ligand
BDBM50067892
(4-Bromophenyl-boronic acid | 4-bromo phenyl boroni...)
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Affinity Data
Ki: 3.60E+3nM
Assay Description:
Inhibitory activity against E. coli AmpC beta-lactamase.
More data for this Ligand-Target Pair
Target Info
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MMDB
KEGG
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B.MOAD
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Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50067892
(4-Bromophenyl-boronic acid | 4-bromo phenyl boroni...)
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Affinity Data
Ki: 7.00E+3nM
Assay Description:
Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Target
Subtilisin BL
(Bacillus lentus)
TBA
Curated by
ChEMBL
Ligand
BDBM50067892
(4-Bromophenyl-boronic acid | 4-bromo phenyl boroni...)
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Affinity Data
Ki: 1.00E+4nM
Assay Description:
Competitive inhibition of Subtilisin BL wild type enzyme from B. lentus
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
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CHEMBL
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Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50067892
(4-Bromophenyl-boronic acid | 4-bromo phenyl boroni...)
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Affinity Data
Ki: 1.17E+4nM
Assay Description:
Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PubMed
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Target
Carbonic anhydrase
(Candida albicans (Yeast))
Universit£
Curated by
ChEMBL
Ligand
BDBM50067892
(4-Bromophenyl-boronic acid | 4-bromo phenyl boroni...)
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Affinity Data
Ki: 1.59E+4nM
Assay Description:
Inhibition of Candida albicans recombinant Carbonic anhydrase preincubated for 15 mins by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
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CHEMBL
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In Depth
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Article
PubMed
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Target
Subtilisin BL
(Bacillus lentus)
TBA
Curated by
ChEMBL
Ligand
BDBM50067892
(4-Bromophenyl-boronic acid | 4-bromo phenyl boroni...)
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Affinity Data
Ki: 2.30E+4nM
Assay Description:
Competitive inhibition of Subtilisin BL M222C-mutated enzyme from B. lentus
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
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CHEMBL
PC cid
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Target
Subtilisin BL
(Bacillus lentus)
TBA
Curated by
ChEMBL
Ligand
BDBM50067892
(4-Bromophenyl-boronic acid | 4-bromo phenyl boroni...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.30E+4nM
Assay Description:
Competitive inhibition of Subtilisin BL wild type enzyme from B. lentus
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
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CHEMBL
PC cid
PC sid
Patents
In Depth
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Article
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Target
Subtilisin Carlsberg
(Bacillus licheniformis)
TBA
Curated by
ChEMBL
Ligand
BDBM50067892
(4-Bromophenyl-boronic acid | 4-bromo phenyl boroni...)
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Affinity Data
Ki: 2.30E+4nM
Assay Description:
Competitive inhibition of Subtilisin Carlsberg enzyme from B. lentus
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
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CHEMBL
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Target
Beta-lactamase TEM
(Escherichia coli)
TBA
Curated by
ChEMBL
Ligand
BDBM50067892
(4-Bromophenyl-boronic acid | 4-bromo phenyl boroni...)
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Affinity Data
Ki: 2.80E+4nM
Assay Description:
Inhibitory constant was determined against class A RTEM-1 Beta-lactamase from Escherichia coli
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Urease
(Glycine max (Soybean))
Banaras Hindu University
Ligand
BDBM50067892
(4-Bromophenyl-boronic acid | 4-bromo phenyl boroni...)
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Affinity Data
Ki: 2.20E+5nM ΔG°: -21.7kJ/mole
pH: 7.0 T: 2°C
Assay Description:
The inhibition studies of soybean urease were initiated with boric acid and boronic acids (butylboronic acid, 4-bromophenylboronic acid, and phenylbo...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI