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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181933(2-(4-(bis(4-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against HCV 1b NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181933(2-(4-(bis(4-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against HCV 1a NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181933(2-(4-(bis(4-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181933(2-(4-(bis(4-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181933(2-(4-(bis(4-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of HCV RNA replication in Huh5-2 cells after 48 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed