Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/mole IC50:  37nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
TargetMannosyl-oligosaccharide alpha-1,2-mannosidase IA(Drosophila melanogaster)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)
Affinity DataKi:  3nMAssay Description:Inhibition of Drosophila melanogaster GM2b by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1,2-mannosidase, putative(Bacteroides thetaiotaomicron )
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3990 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1,2-mannosidase, putative(Bacteroides thetaiotaomicron )
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 2199 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannosyl-oligosaccharide alpha-1,2-mannosidase IA(Drosophila melanogaster)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Drosophila melanogaster GM2b by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)
Affinity DataIC50:  10nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)
Affinity DataIC50:  50nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)
Affinity DataIC50:  400nMAssay Description:Concentration of compound inhibiting alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase 2C1(Rattus norvegicus)
Csiro Division Of Chemicals And Polymers

Curated by ChEMBL
LigandPNGBDBM50016706(CHEMBL63139 | Octahydro-indolizine-1,2,8-triol | S...)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibitory activity against Mannosidase in jack bean (Canavalia ensiformis)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Illinois

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)
Affinity DataIC50: >1.15E+6nMAssay Description:Inhibition of HIV1 RTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed