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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
200
hits in this display
Target
Proto-oncogene tyrosine-protein kinase ROS
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 238nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-tagged ROS1 (unknown origin) (1883 to 2347 residues) expressed in baculovirus infected Sf9 insect...
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase BRSK1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 109nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged BRSK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Tyrosine-protein kinase SYK
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 26nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged SYK expressed in baculovirus expression system using Blk/Lyntide as substrate...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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Target
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 207nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal his-tagged PIM1 expressed in baculovirus expression system using S6K2 peptide as substra...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Target
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 8nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged TYK2 (unknown origin) (871 to 1187 residues) expressed in baculovirus infected Sf9 ins...
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Fibroblast growth factor receptor 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 268nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged FGFR1 (unknown origin) (396 to 820 residues) expressed in baculovirus infected Sf9 ins...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
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Target
Tyrosine-protein kinase ITK/TSK
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 379nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged ITK expressed in baculovirus expression system using srctide as substrate inc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Target
Serine/threonine-protein kinase Sgk3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 322nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged SGK3 (unknown origin) (119 to 496 residues) expressed in baculovirus infec...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Target
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 8nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PDPK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
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Target
Insulin receptor
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 1.86E+3nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged INSR (unknown origin) (1005 to 1310 residues) expressed in baculovirus inf...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Dual specificity protein kinase CLK2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 318nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged CLK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...
More data for this Ligand-Target Pair
Target Info
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Target
Protein kinase C eta type
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 61nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PRKCH (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
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B.MOAD
antibodypedia
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Target
Serine/threonine-protein kinase 4
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 7nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged STK4 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...
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Target Info
PDB
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Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 107nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged DYRK1B (unknown origin) expressed in baculovirus infected Sf9 insect cells inc...
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Target Info
PDB
UniProtKB/SwissProt
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PC sid
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Target
Testis-specific serine/threonine-protein kinase 3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 380nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged TSSK3 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Target Info
UniProtKB/SwissProt
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PubMed
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Target
Focal adhesion kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 401nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged PTK2 expressed in baculovirus expression system incubated for 1 hr by TR-FRET...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC sid
In Depth
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Article
PubMed
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Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 279nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged CSF1R (unknown origin) (538 to 972 residues) expressed in baculovirus infected Sf9 ins...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
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GoogleScholar
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PC sid
In Depth
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Article
PubMed
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Target
Calcium/calmodulin-dependent protein kinase type II subunit gamma
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 8nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged CAMK2G (unknown origin) expressed in baculovirus infected Sf9 insect cells...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
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antibodypedia
GoogleScholar
Ligand Info
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In Depth
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Article
PubMed
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Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 328nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged MAP2K1 (unknown origin) expressed in baculovirus infected Sf9 insect cells inc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
In Depth
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Article
PubMed
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Target
Dual specificity mitogen-activated protein kinase kinase 7
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 293nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged MAP2K7 (1 to 419 residues) expressed in baculovirus expression system using J...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
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Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
Myosin light chain kinase 3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 146nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MYLK3 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
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In Depth
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Target
Tyrosine-protein kinase Blk
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 63nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged BLK expressed in baculovirus expression system using srctide as substrate inc...
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Target Info
Reactome pathway
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Target
Protein kinase C gamma type
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 72nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged PRKCG (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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DrugBank
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In Depth
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Target
Calcium/calmodulin-dependent protein kinase type II subunit alpha
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 15nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged CAMK2A expressed in baculovirus expression system using GS peptide as substra...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
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B.MOAD
antibodypedia
GoogleScholar
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In Depth
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Target
Dual specificity mitogen-activated protein kinase kinase 6
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 28nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged MAP2K6 expressed in baculovirus expression system using p38alpha (9 to 352 re...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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In Depth
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Article
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Target
Serine/threonine-protein kinase N1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 11nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PKN1 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Serine/threonine-protein kinase 3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 6nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged STK3 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Serine/threonine-protein kinase MARK2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 6nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MARK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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PC cid
PC sid
In Depth
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Article
PubMed
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Target
Cyclin-C
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 299nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged CDK8 co-expressed with N-terminal GST-tagged CyclinC expressed in baculovirus...
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Target Info
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Target
Cyclin-C/Cyclin-dependent kinase 19
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 259nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged CDK19 co-expressed with N-terminal GST-tagged CyclinC expressed in baculoviru...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
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Target
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 4nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged RPS6KA3 expressed in baculovirus expression system using S6K peptide as subst...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
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Target
Ribosomal protein S6 kinase alpha-2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 8nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged RPS6KA2 expressed in baculovirus expression system using S6K peptide as subst...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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antibodypedia
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Target
cAMP-dependent protein kinase catalytic subunit alpha
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 116nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged PRKACA expressed in baculovirus expression system using kemptide as substrate...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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DrugBank
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Target
Ribosomal protein S6 kinase beta-1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 40nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged RPS6KB1 T412E mutant expressed in baculovirus expression system using S6K2 pe...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
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antibodypedia
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Target
Serine/threonine-protein kinase MARK1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 9nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged MARK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
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Target
Protein kinase C beta type
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 65nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged PRKCB (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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Serine/threonine-protein kinase Chk1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 20nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal His-tagged CHEK1 expressed in baculovirus expression system using CHKtide as substrate i...
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Target Info
PDB
MMDB
Reactome pathway
KEGG
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Target
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 94nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged CDK2/cyclin A2 expressed in baculovirus expression system using modified Hist...
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Target Info
PDB
MMDB
NCI pathway
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KEGG
UniProtKB/SwissProt
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Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 918nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal His-tagged ABL1 expressed in baculovirus expression system incubated for 1 hr by TR-FRET...
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Target Info
PDB
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KEGG
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Ephrin type-A receptor 4
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 1.10E+3nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged EPHA4 (unknown origin) (586 to 986 residues) expressed in baculovirus infected Sf9 ins...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Serine/threonine-protein kinase MRCK gamma
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 7nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged DMPK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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KEGG
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Target
Tyrosine-protein kinase ZAP-70
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 109nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged ZAP70 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Target Info
PDB
MMDB
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KEGG
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Ephrin type-A receptor 3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 747nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged EPHA3 (unknown origin) (579 to 983 residues) expressed in baculovirus infected Sf9 ins...
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Ephrin type-B receptor 2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 985nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged EPHB2 (unknown origin) (581 to 986 residues) expressed in baculovirus infected Sf9 ins...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Tyrosine-protein kinase TXK
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 1.01E+3nM
Assay Description:
Binding affinity to recombinant human N-terminal GST-tagged TXK (260 to 527 residues) expressed in baculovirus expression system using srctide as sub...
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Ephrin type-A receptor 8
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 1.57E+3nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged EPHB8 (unknown origin) (571 to 924 residues) expressed in baculovirus infected Sf9 ins...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Tyrosine-protein kinase Yes
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 601nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged YES1 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...
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Target Info
PDB
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Target
TGF-beta receptor type-2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 854nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged TGFBR2 (unknown origin) (194 to 567 residues) expressed in baculovirus infected Sf9 in...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
UniProtKB/SwissProt
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Target
Mitogen-activated protein kinase kinase kinase kinase 5
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 87nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MAP4K5 (unknown origin) expressed in baculovirus infected Sf9 insect cells...
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Target Info
NCI pathway
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Target
Non-receptor tyrosine-protein kinase TNK1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 4nM
Assay Description:
Binding affinity to recombinant human N-terminal GST-tagged TNK1 (106 to 390 residues) expressed in baculovirus expression system using CSKtide as su...
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Target
Interleukin-1 receptor-associated kinase 4
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 23nM
Assay Description:
Binding affinity to recombinant full-length human N-terminal his-tagged IRAK4 expressed in baculovirus expression system using IRAK1 peptide as subst...
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Target Info
PDB
MMDB
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KEGG
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Target
Peripheral plasma membrane protein CASK
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 454nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged CASK (unknown origin) (1 to 570 residues) expressed in baculovirus infected Sf9 insect...
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Target Info
PDB
MMDB
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Target
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 1nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PHKG1 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 16nM
Assay Description:
Binding affinity to recombinant full length human N-terminal GST-tagged RPS6KA1 expressed in baculovirus expression system using S6K peptide as subst...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
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Serine/threonine-protein kinase 32B
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 446nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged STK32B (unknown origin) expressed in baculovirus infected Sf9 insect cells...
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Target
Fibroblast growth factor receptor 4
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 718nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged FGFR4 (unknown origin) (460 to 802 residues) expressed in baculovirus infected Sf9 ins...
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase ULK2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 30nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged ULK2 (unknown origin) (1 to 478 residues) expressed in baculovirus infected Sf9 insect...
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Target
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 531nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged TYRO3 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Target Info
PDB
MMDB
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Target
Tyrosine-protein kinase Lyn
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 63nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged LYN (unknown origin) expressed in baculovirus infected Sf9 insect cells in...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Mitogen-activated protein kinase kinase kinase 5
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 136nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MAP3K5 (unknown origin) (654 to 971 residues) expressed in baculovirus inf...
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 313nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged AXL (unknown origin) expressed in baculovirus infected Sf9 insect cells in...
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Target Info
PDB
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Target
Death-associated protein kinase 2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 34nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged DAPK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
More data for this Ligand-Target Pair
Target Info
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MMDB
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Target
Serine/threonine-protein kinase D2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 79nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged PRKD2 (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...
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Target Info
PDB
MMDB
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Target
Serine/threonine-protein kinase Sgk1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 331nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged SGK1 (unknown origin) (60 to 431 residues) expressed in baculovirus infect...
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Target Info
PDB
MMDB
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KEGG
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Target
Serine/threonine-protein kinase LATS2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 135nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged LATS2 (unknown origin) (553 to 1088 residues) expressed in baculovirus inf...
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Target Info
PDB
NCI pathway
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Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 496nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged ERBB4 expressed in baculovirus expression system using srctide as substrate i...
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Target Info
PDB
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Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 165nM
Assay Description:
Binding affinity to recombinant human N-terminal his-tagged PDGFRB (558 to 1106 residues) expressed in baculovirus expression system incubated for 1 ...
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Target Info
PDB
MMDB
NCI pathway
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KEGG
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Target
Fibroblast growth factor receptor 2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 242nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged FGFR2 (unknown origin) (399 to 821 residues) expressed in baculovirus infected Sf9 ins...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Serine/threonine-protein kinase 26
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 687nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged MST4 (unknown origin) expressed in baculovirus infected Sf9 insect cells incub...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Mitogen-activated protein kinase kinase kinase kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 17nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged MAP4K1 (unknown origin) (1 to 346 residues) expressed in baculovirus infected Sf9 inse...
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Serine/threonine-protein kinase 17A
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 258nM
Assay Description:
Binding affinity to recombinant full length N-terminal His-FLAG-GST-tagged STK17A (unknown origin) expressed in baculovirus infected Sf9 insect cells...
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Target
Tyrosine-protein kinase Tec
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 1.06E+3nM
Assay Description:
Binding affinity to recombinant human N-terminal GST-tagged TEC (359 to 631 residues) expressed in baculovirus expression system using Srctide as sub...
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 40nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged RET (unknown origin) (658 to 1114 residues) expressed in baculovirus infected Sf9 inse...
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Target
Dual specificity protein kinase CLK1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 93nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged CLK1 (unknown origin) (129 to 484 residues) expressed in baculovirus infected Sf9 inse...
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Target
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 3nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged MAP3K11 (unknown origin) (99 to 398 residues) expressed in baculovirus infected Sf9 in...
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PDB
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Target
Epithelial discoidin domain-containing receptor 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 674nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged DDR1 (unknown origin) (444 to 876 residues) expressed in baculovirus infected Sf9 inse...
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Target Info
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Target
Serine/threonine-protein kinase PAK 5
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 40nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged PAK7 (unknown origin) (425 to 719 residues) expressed in baculovirus infected Sf9 inse...
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Target Info
PDB
MMDB
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Target
Homeodomain-interacting protein kinase 3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 798nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged HIPK3 (unknown origin) (161 to 562 residues) expressed in baculovirus infected Sf9 ins...
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Target
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 61nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged FLT4 (unknown origin) (798 to 1298 residues) expressed in baculovirus infected Sf9 ins...
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Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 452nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged SRC (unknown origin) expressed in baculovirus infected Sf9 insect cells in...
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Target Info
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Target
Mitogen-activated protein kinase kinase kinase 14
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 352nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged MAP3K14 (unknown origin) (319 to 947 residues) expressed in baculovirus infected Sf9 i...
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Target
Protein kinase C iota type
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 255nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PRKCI (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Target
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 59nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged PTK2B (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...
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Target
STE20-like serine/threonine-protein kinase
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 5nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged SLK (unknown origin) (1 to 1152 residues) expressed in baculovirus infected Sf9 insect...
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Target
Tyrosine-protein kinase Fyn
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 267nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged FYN (unknown origin) expressed in baculovirus infected Sf9 insect cells incuba...
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Target
Activated CDC42 kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 36nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged TNK2 (unknown origin) (110 to 476 residues) expressed in baculovirus infected Sf9 inse...
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Target
Ephrin type-A receptor 7
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 766nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged EPHA7 (unknown origin) ( 595 to 998 residues) expressed in baculovirus infected Sf9 in...
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Target
Tyrosine-protein kinase CSK
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 879nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged CSK (unknown origin) expressed in baculovirus infected Sf9 insect cells incuba...
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Target
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 13nM
Assay Description:
Binding affinity to recombinant human full-length GST N-Terminal tagged-AMPK alpha1/N-Terminal GST tagged-AMPK beta1/N-Terminal his-tagged AMPK gamma...
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Target
Serine/threonine-protein kinase PAK 6
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 22nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged PAK6 expressed in baculovirus expression system using SGKtide as substrate in...
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Target
Tyrosine-protein kinase FRK
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 332nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged FRK (unknown origin) (223 to 505 residues) expressed in baculovirus infect...
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Target
Homeodomain-interacting protein kinase 4
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 424nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged HIPK4 (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...
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Target
Testis-specific serine/threonine-protein kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 18nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged TSSK1B (unknown origin) expressed in baculovirus infected Sf9 insect cells...
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Target
Mitogen-activated protein kinase 12
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 948nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MAPK12 (unknown origin) expressed in baculovirus infected Sf9 insect cells...
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Target
Myotonin-protein kinase
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 90nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged DMPK (unknown origin) expressed in baculovirus infected Sf9 insect cells i...
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Target
cAMP-dependent protein kinase catalytic subunit beta
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 64nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PRKACB (unknown origin) expressed in baculovirus infected Sf9 insect cells...
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Target Info
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Target
Angiopoietin-1 receptor
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 395nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged TEK (unknown origin) (771 to 1124 residues) expressed in baculovirus infec...
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Target
Tyrosine-protein kinase Mer
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 107nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MERTK (unknown origin) (528 to 999 residues) expressed in baculovirus infe...
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Target
Ephrin type-A receptor 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 586nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged EPHA1 (unknown origin) (586 to 976 residues) expressed in baculovirus infe...
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Target
Leukocyte tyrosine kinase receptor
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 193nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged LTK (unknown origin) (498 to 796 residues) expressed in baculovirus infect...
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Target
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 365nM
Assay Description:
Binding affinity to recombinant human N-terminal GST-tagged AKT2 (120 to 481 residues) expressed in baculovirus expression system using crosstide as ...
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Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 94nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged LCK expressed in baculovirus expression system using srctide as substrate inc...
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Target
NUAK family SNF1-like kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 15nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged NUAK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Target
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 894nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged and N-terminal GST-tagged CDK7/cyclinH/MAT1 expressed in baculovirus expressi...
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Target
Myosin-IIIb
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 328nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MYO3B (unknown origin) (1 to 362 residues) expressed in baculovirus infect...
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Target
Rhodopsin kinase GRK1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 122nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged GRK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...
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Target
AP2-associated protein kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 6nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged AAK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...
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Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 14nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged JAK3 (unknown origin) (795 to 1124 residues) expressed in baculovirus infe...
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Hepatocyte growth factor receptor
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 930nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MET (unknown origin) (956 to 1390 residues) expressed in baculovirus infec...
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Myosin light chain kinase, smooth muscle
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 369nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MYLK (unknown origin) (1428 to 1771 residues) expressed in baculovirus inf...
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NT-3 growth factor receptor
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 23nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged NTRK3 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Target
TRAF2 and NCK-interacting protein kinase
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 121nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged TNIK (unknown origin) (1 to 314 residues) expressed in baculovirus infecte...
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Target
cGMP-dependent protein kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 109nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged PRKG1 (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...
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PDB
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Mitogen-activated protein kinase 10
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 315nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MAPK10 (unknown origin) expressed in baculovirus infected Sf9 insect cells...
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Target Info
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MMDB
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Target
ALK tyrosine kinase receptor
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 230nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged ALK (1058 to 1620 residues) expressed in baculovirus expression system using ...
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Serine/threonine-protein kinase 32C
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 448nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged STK32C (unknown origin) (66 to 486 residues) expressed in baculovirus infe...
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Rho-associated protein kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 35nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged ROCK1 (unknown origin) (1 to 477 residues) expressed in baculovirus infect...
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Target Info
PDB
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Target
RAC-gamma serine/threonine-protein kinase
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 749nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged AKT3 (unknown origin) (108 to 479 residues) expressed in baculovirus infec...
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Target Info
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Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 193nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged KDR (790 to 1356 residues) expressed in baculovirus expression system using C...
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Target Info
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Target
Rho-associated protein kinase 2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 23nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged ROCK2 (unknown origin) (1 to 553 residues) expressed in baculovirus infect...
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Misshapen-like kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 228nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MINK1 (unknown origin) (1 to 314 residues) expressed in baculovirus infect...
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Target
Protein kinase C theta type
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 28nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-GST-tagged PRKCQ (unknown origin) expressed in baculovirus infected Sf9 insect cells incub...
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Target Info
PDB
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Glycogen synthase kinase-3 alpha
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 329nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-GST-tagged GSK3A (unknown origin) expressed in baculovirus infected Sf9 insect cells incub...
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Target Info
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Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 230nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged GSK3B (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Target Info
PDB
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Serine/threonine-protein kinase N2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 6nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PKN2 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...
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Serine/threonine-protein kinase PLK4
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 33nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PLK4 (unknown origin) (1 to 836 residues) expressed in baculovirus infecte...
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Target Info
PDB
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Death-associated protein kinase 3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 41nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged DAPK3 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Target Info
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Serine/threonine-protein kinase 32A
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 1.54E+3nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged STK32A (unknown origin) expressed in baculovirus infected Sf9 insect cells inc...
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Protein kinase C zeta type
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 1.25E+3nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PRKCZ (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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PDB
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Citron Rho-interacting kinase
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 747nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged CIT (unknown origin) (1 to 449 residues) expressed in baculovirus infected...
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Serine/threonine-protein kinase SIK2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 4nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged SIK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...
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Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 162nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged CDK9 co-expressed with full length N-terminal His-tagged CyclinT1 expressed i...
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Target
Calcium/calmodulin-dependent protein kinase type II subunit beta
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 19nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged CAMK2B expressed in baculovirus expression system using GS peptide as substra...
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Serine/threonine-protein kinase pim-3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 4nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged PIM3 expressed in baculovirus expression system using S6K2 peptide as substra...
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Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 87nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged CDK5 (1 to 292 residues)/N-terminal His6-tagged p25 (99 to 307 residues) expr...
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Target Info
PDB
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Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 138nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged DYRK1A (unknown origin) expressed in baculovirus infected Sf9 insect cells...
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cGMP-dependent protein kinase 2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 65nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged PRKG2 (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...
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Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 147nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged CHEK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Target Info
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Target
MAP/microtubule affinity-regulating kinase 4
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 6nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged MARK4 (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...
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Target Info
PDB
MMDB
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Target
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 15nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged PIM2 expressed in baculovirus expression system using S6K2 peptide as substra...
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Target
Serine/threonine-protein kinase TAO3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 360nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged TAOK3 expressed in baculovirus expression system using PKC-epsilon peptide as...
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Target
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 13nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MARK3 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Target Info
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Ephrin type-B receptor 6
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 570nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged EPHB6 (unknown origin) (683 to 1130 residues) expressed in baculovirus infected Sf9 in...
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Tyrosine-protein kinase Fes/Fps
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 106nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-tagged FES (unknown origin) expressed in baculovirus infected Sf9 insect cells incubated f...
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Target
Serine/threonine-protein kinase SIK3
(Homo sapiens)
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 10nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged SIK3 (unknown origin) (59 to 365 residues) expressed in baculovirus infected Sf9 insec...
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Target Info
PDB
MMDB
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Serine/threonine-protein kinase TNNI3K
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 844nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged TNNI3K (unknown origin) (1 to 727 residues) expressed in baculovirus infected Sf9 inse...
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PDB
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Target
cAMP-dependent protein kinase catalytic subunit gamma
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 148nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PRKACG (unknown origin) expressed in baculovirus infected Sf9 insect cells...
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Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 14nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged JAK2 (unknown origin) (826 to 1132 residues) expressed in baculovirus infected Sf9 ins...
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Target Info
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Calcium/calmodulin-dependent protein kinase kinase 2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 2nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged CAMKK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells...
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Target Info
PDB
MMDB
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KEGG
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Target
Interleukin-1 receptor-associated kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 299nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged IRAK1 (unknown origin) (194 to 712 residues) expressed in baculovirus infected Sf9 ins...
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Target Info
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Target
Serine/threonine-protein kinase DCLK3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 60nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged DCLK3 (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...
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Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 5nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged PAK4 expressed in baculovirus expression system using SGKtide as substrate in...
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Target Info
PDB
MMDB
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Target
Cytoplasmic tyrosine-protein kinase BMX
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 696nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged BMX expressed in baculovirus expression system using Srctide as substrate inc...
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Target Info
PDB
MMDB
NCI pathway
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Target
Mitogen-activated protein kinase kinase kinase kinase 2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 6nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MAP4K2 (unknown origin) expressed in baculovirus infected Sf9 insect cells...
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Target Info
MMDB
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KEGG
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Target
Serine/threonine-protein kinase SIK1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 3nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged SIK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells incub...
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Target Info
NCI pathway
Reactome pathway
KEGG
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Death-associated protein kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 69nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged DAPK1 (unknown origin) (1 to 289 residues) expressed in baculovirus infect...
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Target Info
PDB
MMDB
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Serine/threonine-protein kinase TAO1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 25nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged TAOK1 (unknown origin) (1 to 314 residues) expressed in baculovirus infect...
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Target Info
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Target
Protein kinase C delta type
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 13nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged PRKCD expressed in baculovirus expression system using PKC peptide as substra...
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Target Info
PDB
MMDB
NCI pathway
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KEGG
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Ephrin type-B receptor 4
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 1.80E+3nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged EPHB4 (unknown origin) (577 to 987 residues) expressed in baculovirus infected Sf9 ins...
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Target Info
PDB
MMDB
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KEGG
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Serine/threonine-protein kinase 38-like
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 759nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged STK38L (unknown origin) expressed in baculovirus infected Sf9 insect cells...
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Target
LIM domain kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 6nM
Assay Description:
Binding affinity to truncated human N-terminal GST-tagged LIMK1 (285 to 638 residues) expressed in baculovirus expression system using cofilin2 as su...
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Target Info
PDB
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KEGG
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Mitogen-activated protein kinase 15
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 113nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MAPK15 (unknown origin) expressed in baculovirus infected Sf9 insect cells...
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Serine/threonine-protein kinase ULK1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 135nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged ULK1 (unknown origin) (1 to 649 residues) expressed in baculovirus infected Sf9 insect...
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Target Info
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Target
Fibroblast growth factor receptor 3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 409nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged FGFR3 (unknown origin) (436 to 806 residues) expressed in baculovirus infected Sf9 ins...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 286nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged MAPK8 (unknown origin) (2 to 364 residues) expressed in baculovirus infected Sf9 insec...
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Target Info
PDB
MMDB
NCI pathway
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KEGG
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Target
Tyrosine-protein kinase ABL2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 531nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged ABL2 (unknown origin) (2 to 52 and 74 to 1182 residues) expressed in bacul...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Serine/threonine-protein kinase 24
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 436nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged STK24 (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Target
Calcium/calmodulin-dependent protein kinase type II subunit delta
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 4nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged CAMK2D expressed in baculovirus expression system using GS peptide as substra...
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Target Info
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UniProtKB/SwissProt
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Target
Serine/threonine-protein kinase Sgk2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 1.22E+3nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged SGK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells incub...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
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Target
Mitogen-activated protein kinase kinase kinase 2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 38nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MAP3K2 (unknown origin) (337 to 620 residues) expressed in baculovirus inf...
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Target Info
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MMDB
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Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 44nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged MAP3K7 (unknown origin) expressed in baculovirus infected Sf9 insect cells inc...
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Target Info
PDB
MMDB
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Target
Serine/threonine-protein kinase MRCK alpha
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 43nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged CDC42BPA (unknown origin) (1 to 574 residues) expressed in baculovirus inf...
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Target Info
PDB
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Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 17nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged TBK1 expressed in baculovirus expression system using CKtide as substrate inc...
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Target Info
PDB
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KEGG
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Target
Protein kinase C alpha type
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 92nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PRKCA (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
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Target
Protein kinase C epsilon type
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 41nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged PRKCE expressed in baculovirus expression system using PKC peptide as substra...
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Target Info
PDB
MMDB
NCI pathway
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KEGG
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Target
Serine/threonine-protein kinase 16
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 365nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged STK16 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Target Info
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Target
Mitogen-activated protein kinase kinase kinase 9
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 2nM
Assay Description:
Binding affinity to recombinant N-terminal His-FLAG-GST-tagged MAP3K9 (unknown origin) (110 to 422 residues) expressed in baculovirus infected Sf9 in...
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
MAP kinase-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 162nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged MKNK2 expressed in baculovirus expression system using RS peptide as substrat...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Target
Calcium/calmodulin-dependent protein kinase kinase 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 11nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged CAMKK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
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Tyrosine-protein kinase BTK
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 374nM
Assay Description:
Binding affinity to recombinant human full-length N-terminal GST-tagged BTK expressed in baculovirus expression system using srctide as substrate inc...
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Target Info
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Aurora kinase A
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 45nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged AURKA (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Target Info
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NUAK family SNF1-like kinase 2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 10nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged NUAK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...
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Tyrosine-protein kinase Fer
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 27nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged FER (unknown origin) expressed in baculovirus infected Sf9 insect cells in...
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Tyrosine-protein kinase HCK
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 263nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged HCK (unknown origin) (25 to 526 residues) expressed in baculovirus infecte...
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Target Info
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5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 45nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PRKAA2 (unknown origin) (10 to 552 residues) expressed in baculovirus infe...
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Serine/threonine-protein kinase 25
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 444nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged STK25 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Calcium/calmodulin-dependent protein kinase type 1G
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 326nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged CAMK1G (unknown origin) expressed in baculovirus infected Sf9 insect cells...
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Dual specificity protein kinase CLK4
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 90nM
Assay Description:
Binding affinity to recombinant human full length N-terminal GST-tagged CLK4 expressed in baculovirus expression system incubated for 1 hr by TR-FRET...
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Serine/threonine-protein kinase ULK3
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 16nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged ULK3 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...
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Maternal embryonic leucine zipper kinase
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 50nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MELK (unknown origin) (1 to 493 residues) expressed in baculovirus infecte...
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BMP-2-inducible protein kinase
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 24nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged BMP2K (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Serine/threonine-protein kinase 33
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 8nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged STK33 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 345nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged RPS6KA5 (unknown origin) expressed in baculovirus infected Sf9 insect cell...
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Target Info
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High affinity nerve growth factor receptor
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 35nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged NTRK1 (unknown origin) (436 to 790 residues) expressed in baculovirus infe...
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Ribosomal protein S6 kinase alpha-6
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 21nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged RPS6KA6 (unknown origin) expressed in baculovirus infected Sf9 insect cells in...
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[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 5nM
Assay Description:
Binding affinity to recombinant human full length N-terminal his-tagged PDK1 expressed in baculovirus infected Sf9 insect cells incubated for 1 hr by...
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Tyrosine-protein kinase Fgr
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 101nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-tagged FGR (unknown origin) expressed in baculovirus infected Sf9 insect cells incuba...
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Phosphorylase b kinase gamma catalytic chain, liver/testis isoform
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 71nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PHKG2 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Inhibitor of nuclear factor kappa-B kinase subunit epsilon
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 58nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged IKBKE (unknown origin) expressed in baculovirus infected Sf9 insect cells ...
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Target
cAMP-dependent protein kinase catalytic subunit PRKX
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50505541
(CHEMBL4465866)
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Affinity Data
Kd: 43nM
Assay Description:
Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PRKX (unknown origin) expressed in baculovirus infected Sf9 insect cells i...
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