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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
19
hits in this display
Target
Mitogen-activated protein kinase 14
(Mus musculus (mouse))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: 18nM
Assay Description:
Inhibition of murine phosphorylated His-Mitogen-activated protein kinase p38 alpha.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Mitogen-activated protein kinase 9
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: 261nM
Assay Description:
Inhibition of human c-Jun N-terminal kinase 2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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Target
Epidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: 280nM
Assay Description:
Inhibition of human epidermal growth factor receptor
More data for this Ligand-Target Pair
Target Info
PDB
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antibodypedia
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: 700nM
Assay Description:
Inhibition of human epidermal growth factor receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: 1.10E+3nM
Assay Description:
Inhibition of human Epidermal growth factor receptor, HER-1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: 1.70E+3nM
Assay Description:
Inhibition of human vascular endothelial growth factor receptor 2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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Article
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Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: 1.90E+3nM
Assay Description:
Inhibition of human c-Jun N-terminal kinase 1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
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Article
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: >2.00E+3nM
Assay Description:
Inhibition of human cytochrome P450 3A4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: >2.00E+3nM
Assay Description:
Inhibition of human cytochrome P450 2D6
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: >2.00E+3nM
Assay Description:
Inhibition of human cytochrome P450 1A2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: >2.00E+3nM
Assay Description:
Inhibition of human cytochrome P450 2C9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: 2.10E+3nM
Assay Description:
Inhibition of human RAF proto-oncogene serine/threonine-protein kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: 8.00E+3nM
Assay Description:
Inhibition of human c-Src
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human Met proto-oncogene tyrosine kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Cyclin-dependent kinase 1
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human cyclin-dependent kinase 1
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human c-Kit kinase
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human c-Abl
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human insulin-like growth factor I receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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antibodypedia
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CHEMBL
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Target
Prostaglandin G/H synthase 1
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50404281
(CHEMBL2111784)
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Affinity Data
IC50: >8.00E+4nM
Assay Description:
Inhibition of human prostaglandin G/H synthase 1, COX-1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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