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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Mitogen-activated protein kinase kinase kinase 5
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50212270
(CHEMBL3952214)
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Affinity Data
IC50: 13nM
Assay Description:
Inhibition of recombinant human N-terminal GST-tagged ASK1 catalytic domain (654 to 971 residues) expressed in baculovirus infected sf21 cells using ...
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Target Info
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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3D Structure (crystal)
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Target
Mitogen-activated protein kinase kinase kinase 5
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50212270
(CHEMBL3952214)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of ASK1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 5
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50212270
(CHEMBL3952214)
Copy SMILES
Copy InChI
Affinity Data
IC50: 14nM
Assay Description:
Inhibition of ASK1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
Takeda Research In California
Curated by
ChEMBL
Ligand
BDBM50212270
(CHEMBL3952214)
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Affinity Data
IC50: 63nM
Assay Description:
Inhibition of CDK2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Takeda Research In California
Curated by
ChEMBL
Ligand
BDBM50212270
(CHEMBL3952214)
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Affinity Data
IC50: 63nM
Assay Description:
Inhibition of RET (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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UniProtKB/SwissProt
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antibodypedia
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Ligand Info
CHEMBL
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In Depth
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Article
PubMed
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Target
5'-AMP-activated protein kinase catalytic subunit alpha-1
(Homo sapiens (Human))
Takeda Research In California
Curated by
ChEMBL
Ligand
BDBM50212270
(CHEMBL3952214)
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Affinity Data
IC50: 200nM
Assay Description:
Inhibition of PRKKA1 (unknown origin)
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Target Info
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Target
Tyrosine-protein kinase Mer
(Homo sapiens (Human))
Takeda Research In California
Curated by
ChEMBL
Ligand
BDBM50212270
(CHEMBL3952214)
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Affinity Data
IC50: 631nM
Assay Description:
Inhibition of MER (unknown origin)
More data for this Ligand-Target Pair
Target Info
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MMDB
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PubMed
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Target
Rho-associated protein kinase 1
(Homo sapiens (Human))
Takeda Research In California
Curated by
ChEMBL
Ligand
BDBM50212270
(CHEMBL3952214)
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Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibition of ROCK1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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MMDB
NCI pathway
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Article
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Target
Tyrosine-protein kinase ITK/TSK
(Homo sapiens (Human))
Takeda Research In California
Curated by
ChEMBL
Ligand
BDBM50212270
(CHEMBL3952214)
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Affinity Data
IC50: 1.26E+3nM
Assay Description:
Inhibition of ITK (unknown origin)
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
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Ligand Info
CHEMBL
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In Depth
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Article
PubMed
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Takeda Research In California
Curated by
ChEMBL
Ligand
BDBM50212270
(CHEMBL3952214)
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Affinity Data
IC50: <2.00E+4nM
Assay Description:
Inhibition of EGFR (unknown origin)
More data for this Ligand-Target Pair
Target Info
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MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Takeda Research In California
Curated by
ChEMBL
Ligand
BDBM50212270
(CHEMBL3952214)
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Affinity Data
IC50: <2.00E+4nM
Assay Description:
Inhibition of ERBB4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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Target
Ephrin type-A receptor 3
(Homo sapiens (Human))
Takeda Research In California
Curated by
ChEMBL
Ligand
BDBM50212270
(CHEMBL3952214)
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Affinity Data
IC50: <2.00E+4nM
Assay Description:
Inhibition of EPHA3 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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UniProtKB/SwissProt
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antibodypedia
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Ligand Info
CHEMBL
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In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human))
Takeda Research In California
Curated by
ChEMBL
Ligand
BDBM50212270
(CHEMBL3952214)
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Affinity Data
IC50: <2.00E+4nM
Assay Description:
Inhibition of p38 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Takeda Research In California
Curated by
ChEMBL
Ligand
BDBM50212270
(CHEMBL3952214)
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Copy InChI
Affinity Data
IC50: <2.00E+4nM
Assay Description:
Inhibition of HER4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI