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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Cystic fibrosis transmembrane conductance regulator [1-507,509-1480]
(Homo sapiens (Human))
Flatley Discovery Lab
US Patent
Ligand
BDBM160509
(US10280160, Example 1. | US9682969, 1)
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Affinity Data
EC50: <1.00E+4nM
Assay Description:
This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Cystic fibrosis transmembrane conductance regulator
(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM160509
(US10280160, Example 1. | US9682969, 1)
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Affinity Data
EC50: <1.00E+4nM
Assay Description:
Inhibition of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing YFP-H148Q/I152L 25,22 incubated for 60 to 120 mins in presence ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cystic fibrosis transmembrane conductance regulator
(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM160509
(US10280160, Example 1. | US9682969, 1)
Copy SMILES
Copy InChI
Affinity Data
EC50: <1.00E+4nM
Assay Description:
Fisher Rat Thyroid (FRT) cells stably expressing both human F508del CFTR and a halide-sensitive yellow fluorescent protein (YFP-H148Q/I152L 25,22) (G...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI