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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
460
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Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
IC50: 0.690nM
Assay Description:
Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarization
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Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
IC50: 0.690nM
Assay Description:
Inhibition of FMS
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Target
Macrophage colony-stimulating factor 1 receptor
(Mus musculus (Mouse))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
IC50: 2.60nM
Assay Description:
Inhibition of FMS-mediated proliferation in CSF1-stimulated bone marrow-derived mouse macrophages assessed as inhibition of incorporation of bromodeo...
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
IC50: 5nM
Assay Description:
Inhibition of KIT
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Target
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
IC50: 12nM
Assay Description:
Inhibition of AXL
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
IC50: 15nM
Assay Description:
Inhibition of TRKA
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
IC50: 21nM
Assay Description:
Inhibition of FLT3 in human MV411 cells assessed as inhibition of cell proliferation after 72 hrs by CellTiter-Glo assay
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
IC50: 30nM
Assay Description:
Inhibition of FLT3
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
IC50: 41nM
Assay Description:
Inhibition of KIT in human Mo7e cells assessed as inhibition of SCF-induced cell proliferation after 72 hrs by CellTiter-Glo assay
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Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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IC50: 88nM
Assay Description:
Inhibition of LCK
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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IC50: 150nM
Assay Description:
Inhibition of TRKA in human TF1 cells assessed as inhibition of NGF-induced cell proliferation after 72 hrs by CellTiter-Glo assay
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Target
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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IC50: 2.60E+3nM
Assay Description:
Inhibition of AXL overexpressed in human HEK cells assessed as inhibition of GAS6-induced autophosphorylation by immunoblot assay
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Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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IC50: 3.90E+3nM
Assay Description:
Inhibition of LCK in human Jurkat cells assessed as inhibition of PMA and antiCD3-induced IL2 secretion after 24 hrs by ELISA
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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IC50: 4.80E+3nM
Assay Description:
Inhibition of CYP3A4
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP1A2
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2C9
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2C19
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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IC50: >1.00E+4nM
Assay Description:
Displacement of [3H]astemizole from human ERG potassium channel
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.50E+3nM
Assay Description:
Binding constant for ABL1(F317L)-nonphosphorylated kinase domain
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Target
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 700nM
Assay Description:
Binding constant for FLT4 kinase domain
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Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 5.40E+3nM
Assay Description:
Binding constant for MET(Y1235D) kinase domain
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Target
Serine/threonine-protein kinase MRCK gamma
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for DMPK2 kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 280nM
Assay Description:
Binding constant for ABL1(H396P)-nonphosphorylated kinase domain
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Target
Serine/threonine-protein kinase TNNI3K
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for TNNI3K kinase domain
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 48nM
Assay Description:
Binding constant for KIT(D816H) kinase domain
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for EGFR(L747-S752del, P753S) kinase domain
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Target
Ribosomal protein S6 kinase alpha-6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for RSK4(Kin.Dom.2-C-terminal) kinase domain
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for EGFR kinase domain
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Target
Serine/threonine-protein kinase BRSK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for BRSK1 kinase domain
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(E545A) kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 930nM
Assay Description:
Binding constant for ABL1(T315I)-nonphosphorylated kinase domain
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.40nM
Assay Description:
Binding constant for FLT3(D835H) kinase domain
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Target
Calcium/calmodulin-dependent protein kinase type II subunit alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2A kinase domain
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.20nM
Assay Description:
Binding constant for RET(V804L) kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 670nM
Assay Description:
Binding constant for ABL1-nonphosphorylated kinase domain
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(H1047Y) kinase domain
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Target
Myosin light chain kinase, smooth muscle
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 590nM
Assay Description:
Binding constant for MYLK kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 370nM
Assay Description:
Binding constant for ABL1(E255K)-phosphorylated kinase domain
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Target
Ephrin type-A receptor 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 4.40E+3nM
Assay Description:
Binding constant for EPHA6 kinase domain
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Target
Insulin receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 330nM
Assay Description:
Binding constant for INSR kinase domain
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 39nM
Assay Description:
Binding constant for KIT(V559D,T670I) kinase domain
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for EGFR(E746-A750del) kinase domain
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 0.830nM
Assay Description:
Binding constant for RET(V804M) kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 390nM
Assay Description:
Binding constant for ABL1-phosphorylated kinase domain
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Target
Aurora kinase B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.90E+3nM
Assay Description:
Binding constant for AURKB kinase domain
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 18nM
Assay Description:
Binding constant for KIT(D816V) kinase domain
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Target
Interleukin-1 receptor-associated kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for IRAK3 kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 230nM
Assay Description:
Binding constant for ABL1(M351T)-phosphorylated kinase domain
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Target
Inhibitor of nuclear factor kappa-B kinase subunit alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for IKK-alpha kinase domain
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.60nM
Assay Description:
Binding constant for KIT kinase domain
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(H1047L) kinase domain
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(I800L) kinase domain
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Target
Cyclin-dependent kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 5.00E+3nM
Assay Description:
Binding constant for CDK4-cyclinD1 kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 350nM
Assay Description:
Binding constant for ABL1(Y253F)-phosphorylated kinase domain
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Target
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for BRAF kinase domain
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Target Info
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for EGFR(G719S) kinase domain
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(M1043I) kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.20E+3nM
Assay Description:
Binding constant for ABL1(F317L)-phosphorylated kinase domain
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for EGFR(L747-T751del,Sins) kinase domain
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 6.40nM
Assay Description:
Binding constant for RET(M918T) kinase domain
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Target
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 9.90nM
Assay Description:
Binding constant for CHEK1 kinase domain
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Target
Calcium/calmodulin-dependent protein kinase kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMKK2 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 6.70E+3nM
Assay Description:
Binding constant for MAP3K4 kinase domain
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Target
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA5(Kin.Dom.1-N-terminal) kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 230nM
Assay Description:
Binding constant for ABL1(Q252H)-phosphorylated kinase domain
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Target
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for RSK1(Kin.Dom.2-C-terminal) kinase domain
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Target
Myosin-IIIb
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MYO3B kinase domain
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Target
Fibroblast growth factor receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.10E+3nM
Assay Description:
Binding constant for FGFR3 kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
Kd: 8.60E+3nM
Assay Description:
Binding constant for ABL1(F317I)-nonphosphorylated kinase domain
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Target
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 6.20E+3nM
Assay Description:
Binding constant for MARK3 kinase domain
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Target
Ribosomal protein S6 kinase alpha-4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.20E+3nM
Assay Description:
Binding constant for RPS6KA4(Kin.Dom.1-N-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
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Target
Myotonin-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DMPK kinase domain
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Target
Serine/threonine-protein kinase 17A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
Kd: 270nM
Assay Description:
Binding constant for DRAK1 kinase domain
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Target
Protein kinase C eta type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCH kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 4.50E+3nM
Assay Description:
Binding constant for ABL1(F317I)-phosphorylated kinase domain
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Target
SRSF protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.20E+3nM
Assay Description:
Binding constant for SRPK2 kinase domain
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Target
Macrophage-stimulating protein receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MST1R kinase domain
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
Kd: 60nM
Assay Description:
Binding constant for KIT(A829P) kinase domain
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.30nM
Assay Description:
Binding constant for KIT(L576P) kinase domain
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Target
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 470nM
Assay Description:
Binding constant for TYK2(JH2domain-pseudokinase) kinase domain
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for EGFR(G719C) kinase domain
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
Kd: 6.80E+3nM
Assay Description:
Binding constant for EGFR(L747-E749del, A750P) kinase domain
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Target
Calcium/calmodulin-dependent protein kinase type II subunit beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2B kinase domain
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Target
Rho-associated protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ROCK2 kinase domain
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Target
Ribosomal protein S6 kinase alpha-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.30E+3nM
Assay Description:
Binding constant for RSK3(Kin.Dom.1-N-terminal) kinase domain
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(Q546K) kinase domain
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
Copy SMILES
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Kd: 17nM
Assay Description:
Binding constant for FLT3 kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 440nM
Assay Description:
Binding constant for ABL1(H396P)-phosphorylated kinase domain
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Target
cGMP-dependent protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKG1 kinase domain
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(E542K) kinase domain
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Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 4.10E+3nM
Assay Description:
Binding constant for MET(M1250T) kinase domain
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Target
Death-associated protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 5.00E+3nM
Assay Description:
Binding constant for DAPK1 kinase domain
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Target
Cyclin-dependent kinase 11A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDC2L2 kinase domain
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
Kd: 240nM
Assay Description:
Binding constant for EGFR(L858R,T790M) kinase domain
More data for this Ligand-Target Pair
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
Copy SMILES
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Kd: 1.10E+3nM
Assay Description:
Binding constant for EGFR(T790M) kinase domain
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Target
eIF-2-alpha kinase GCN2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 81nM
Assay Description:
Binding constant for GCN2(Kin.Dom.2,S808G) kinase domain
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EGFR(L858R) kinase domain
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
Kd: 13nM
Assay Description:
Binding constant for FLT3(N841I) kinase domain
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Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 370nM
Assay Description:
Binding constant for LRRK2(G2019S) kinase domain
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Target
Tyrosine-protein kinase JAK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
Copy SMILES
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Affinity Data
Kd: 140nM
Assay Description:
Binding constant for JAK1(JH2domain-pseudokinase) kinase domain
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
Copy SMILES
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Affinity Data
Kd: 20nM
Assay Description:
Binding constant for FLT3(K663Q) kinase domain
More data for this Ligand-Target Pair
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Misshapen-like kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
Kd: 81nM
Assay Description:
Binding constant for MINK kinase domain
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
Copy SMILES
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Affinity Data
Kd: 4.20nM
Assay Description:
Binding constant for FLT3(ITD) kinase domain
More data for this Ligand-Target Pair
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
Copy SMILES
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Affinity Data
Kd: 1.5nM
Assay Description:
Binding constant for FLT3(D835Y) kinase domain
More data for this Ligand-Target Pair
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
Copy SMILES
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Affinity Data
Kd: 6nM
Assay Description:
Binding constant for KIT(V559D,V654A) kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 180nM
Assay Description:
Binding constant for ABL1(T315I)-phosphorylated kinase domain
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 9.60E+3nM
Assay Description:
Binding constant for EGFR(L861Q) kinase domain
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Target
AP2-associated protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 520nM
Assay Description:
Binding constant for AAK1 kinase domain
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Target
Ephrin type-A receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 6.80E+3nM
Assay Description:
Binding constant for EPHA1 kinase domain
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(C420R) kinase domain
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Target
Serine/threonine-protein kinase D2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 320nM
Assay Description:
Binding constant for PRKD2 kinase domain
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Target
Cyclin-dependent kinase 2 homolog
(Plasmodium falciparum (isolate 3D7))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PFPK5(P.falciparum) kinase domain
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Target
Dual specificity protein kinase CLK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 900nM
Assay Description:
Binding constant for CLK1 kinase domain
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Target
NT-3 growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 68nM
Assay Description:
Binding constant for TRKC kinase domain
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Target
Mitogen-activated protein kinase 12
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for p38-gamma kinase domain
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Target
Tyrosine-protein kinase Mer
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 86nM
Assay Description:
Binding constant for MERTK kinase domain
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Target
Aurora kinase C
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.00E+3nM
Assay Description:
Binding constant for AURKC kinase domain
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Target
Calcium/calmodulin-dependent protein kinase type II subunit delta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2D kinase domain
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Serine/threonine-protein kinase tousled-like 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for TLK2 kinase domain
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5'-AMP-activated protein kinase catalytic subunit alpha-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 200nM
Assay Description:
Binding constant for AMPK-alpha1 kinase domain
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Target
Serine/threonine-protein kinase SIK3 [59-1321]
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for QSK kinase domain
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Serine/threonine-protein kinase 16
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 18nM
Assay Description:
Binding constant for STK16 kinase domain
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Target
Cyclin-dependent kinase 17
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PCTK2 kinase domain
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Target
Discoidin domain-containing receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 100nM
Assay Description:
Binding constant for DDR2 kinase domain
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Target
Serine/threonine-protein kinase receptor R3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.90E+3nM
Assay Description:
Binding constant for ACVRL1 kinase domain
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Target
Tyrosine-protein kinase BTK
(Homo sapiens (Human))
Ambit Biosciences
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ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 77nM
Assay Description:
Binding constant for BTK kinase domain
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Target
Cyclin-dependent kinase 4
(Homo sapiens (Human))
Ambit Biosciences
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ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK4-cyclinD1 kinase domain
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Target
Fibroblast growth factor receptor 3
(Homo sapiens (Human))
Ambit Biosciences
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ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.60E+3nM
Assay Description:
Binding constant for FGFR3 kinase domain
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Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 18nM
Assay Description:
Binding constant for JAK3(JH1domain-catalytic) kinase domain
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 7.70nM
Assay Description:
Binding constant for KIT(V559D) kinase domain
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Target
Cyclin-dependent kinase 16
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PCTK1 kinase domain
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Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 27nM
Assay Description:
Binding constant for PDGFRA kinase domain
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Target
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
(Homo sapiens (Human))
Ambit Biosciences
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ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 590nM
Assay Description:
Binding constant for PHKG1 kinase domain
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(E545K) kinase domain
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CB kinase domain
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Target
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 4.10nM
Assay Description:
Binding constant for AMPK-alpha2 kinase domain
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Target
Protein kinase C delta type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCD kinase domain
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Target
Serine/threonine-protein kinase N2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 4.70E+3nM
Assay Description:
Binding constant for PKN2 kinase domain
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Target
Protein kinase C theta type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCQ kinase domain
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Target
cGMP-dependent protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKG2 kinase domain
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Target
Serine/threonine-protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 160nM
Assay Description:
Binding constant for MST2 kinase domain
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Target
Serine/threonine-protein kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 48nM
Assay Description:
Binding constant for MST1 kinase domain
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Target
Dual specificity testis-specific protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for TESK1 kinase domain
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Target
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for TYRO3 kinase domain
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Target
Serine/threonine-protein kinase VRK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for VRK2 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 12
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 330nM
Assay Description:
Binding constant for DLK kinase domain
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Target
Serine/threonine-protein kinase 25
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.10E+3nM
Assay Description:
Binding constant for YSK1 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 86nM
Assay Description:
Binding constant for MAP3K2 kinase domain
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Target
Serine/threonine-protein kinase PLK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PLK2 kinase domain
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Target
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 620nM
Assay Description:
Binding constant for PIM2 kinase domain
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Target
Citron Rho-interacting kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CIT kinase domain
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Target
Serine/threonine-protein kinase 38
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for NDR1 kinase domain
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Target
Serine/threonine-protein kinase Nek1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK1 kinase domain
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Target
Ephrin type-B receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.30E+3nM
Assay Description:
Binding constant for EPHB2 kinase domain
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Target
Serine/threonine-protein kinase MARK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.30E+3nM
Assay Description:
Binding constant for MARK2 kinase domain
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Target
MAP kinase-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MKNK2 kinase domain
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Target
BMP-2-inducible protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 140nM
Assay Description:
Binding constant for BIKE kinase domain
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Target
Transient receptor potential cation channel subfamily M member 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for TRPM6 kinase domain
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Target
SNF-related serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for SNRK kinase domain
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Target
Serine/threonine-protein kinase RIO2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for RIOK2 kinase domain
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Target
Serine/threonine-protein kinase 32B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for YANK2 kinase domain
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Target
Serine/threonine-protein kinase MARK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 4.20E+3nM
Assay Description:
Binding constant for MARK1 kinase domain
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Target
Glycogen synthase kinase-3 alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 380nM
Assay Description:
Binding constant for GSK3A kinase domain
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Target
Serine/threonine-protein kinase PAK 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 5.60E+3nM
Assay Description:
Binding constant for PAK6 kinase domain
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Target
Atypical kinase COQ8A, mitochondrial
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ADCK3 kinase domain
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Target
Serine/threonine-protein kinase PAK 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 410nM
Assay Description:
Binding constant for PAK7 kinase domain
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Target
Calcium/calmodulin-dependent protein kinase type 1D
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 6.60E+3nM
Assay Description:
Binding constant for CAMK1D kinase domain
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Target
Calcium/calmodulin-dependent protein kinase type 1G
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 6.20E+3nM
Assay Description:
Binding constant for CAMK1G kinase domain
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Target
Ephrin type-A receptor 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA8 kinase domain
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 9.20nM
Assay Description:
Binding constant for RET kinase domain
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Target
Receptor-interacting serine/threonine-protein kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for RIPK4 kinase domain
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Target
Dual specificity protein kinase CLK4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.30E+3nM
Assay Description:
Binding constant for CLK4 kinase domain
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Target
Serine/threonine-protein kinase TAO1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.70E+3nM
Assay Description:
Binding constant for TAOK1 kinase domain
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Target
Casein kinase I isoform gamma-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1G1 kinase domain
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Target
Homeodomain-interacting protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.60E+3nM
Assay Description:
Binding constant for HIPK2 kinase domain
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Target
Fibroblast growth factor receptor 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR4 kinase domain
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Target
Fibroblast growth factor receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.60E+3nM
Assay Description:
Binding constant for FGFR2 kinase domain
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Target
Fibroblast growth factor receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.50E+3nM
Assay Description:
Binding constant for FGFR1 kinase domain
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Target
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIP5K2C kinase domain
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Target
Atypical kinase COQ8B, mitochondrial
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ADCK4 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 19
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 39nM
Assay Description:
Binding constant for YSK4 kinase domain
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Target
Dual specificity mitogen-activated protein kinase kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 420nM
Assay Description:
Binding constant for MEK2 kinase domain
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Target
Serine/threonine-protein kinase 33
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 780nM
Assay Description:
Binding constant for STK33 kinase domain
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Target
NUAK family SNF1-like kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 130nM
Assay Description:
Binding constant for SNARK kinase domain
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Target
MAP/microtubule affinity-regulating kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 5.30E+3nM
Assay Description:
Binding constant for MARK4 kinase domain
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Target
Serine/threonine-protein kinase RIO1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.30E+3nM
Assay Description:
Binding constant for RIOK1 kinase domain
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Target
Testis-specific serine/threonine-protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.20E+3nM
Assay Description:
Binding constant for TSSK1B kinase domain
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Target
Calcium/calmodulin-dependent protein kinase kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.80E+3nM
Assay Description:
Binding constant for CAMKK1 kinase domain
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Target
MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MAPKAPK2 kinase domain
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Target
Serine/threonine-protein kinase Nek9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK9 kinase domain
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Target
Myosin light chain kinase 2, skeletal/cardiac muscle
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MYLK2 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MLK1 kinase domain
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Target
Serine/threonine-protein kinase DCLK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for DCAMKL3 kinase domain
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Target
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis)
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 170nM
Assay Description:
Binding constant for PKNB(M.tuberculosis) kinase domain
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Target
Cyclin-dependent kinase 11B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDC2L1 kinase domain
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Target
Tyrosine-protein kinase Srms
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for SRMS kinase domain
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Target
Serine/threonine-protein kinase 35
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.20E+3nM
Assay Description:
Binding constant for STK35 kinase domain
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Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for DYRK1A kinase domain
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Target
Serine/threonine-protein kinase Nek7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK7 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 20
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ZAK kinase domain
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Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK2 kinase domain
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for p38-alpha kinase domain
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Target
Mitogen-activated protein kinase 15
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK8 kinase domain
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Target
Casein kinase I isoform delta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1D kinase domain
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Target
Mitogen-activated protein kinase 9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.40E+3nM
Assay Description:
Binding constant for JNK2 kinase domain
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Target
Cyclin-dependent kinase 15
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PFTAIRE2 kinase domain
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Target
Rhodopsin kinase GRK7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 820nM
Assay Description:
Binding constant for GRK7 kinase domain
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Target
Homeodomain-interacting protein kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for HIPK4 kinase domain
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Target
Dual specificity mitogen-activated protein kinase kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 99nM
Assay Description:
Binding constant for MEK5 kinase domain
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Target
Dual specificity mitogen-activated protein kinase kinase 7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MKK7 kinase domain
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Target
Casein kinase I isoform alpha-like
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1A1L kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 7.20nM
Assay Description:
Binding constant for TAK1 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 140nM
Assay Description:
Binding constant for MAP4K4 kinase domain
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Target
Serine/threonine-protein kinase tousled-like 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for TLK1 kinase domain
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Target
Cyclin-dependent kinase 14
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PFTK1 kinase domain
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Target
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIP5K1C kinase domain
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Target
STE20/SPS1-related proline-alanine-rich protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for STK39 kinase domain
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Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 470nM
Assay Description:
Binding constant for TBK1 kinase domain
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Serine/threonine-protein kinase Sgk3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for SGK3 kinase domain
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Inhibitor of nuclear factor kappa-B kinase subunit epsilon
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.30E+3nM
Assay Description:
Binding constant for IKK-epsilon kinase domain
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Insulin receptor-related protein
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.20E+3nM
Assay Description:
Binding constant for INSRR kinase domain
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Serine/threonine-protein kinase PLK4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 31nM
Assay Description:
Binding constant for PLK4 kinase domain
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SRSF protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 6.00E+3nM
Assay Description:
Binding constant for SRPK3 kinase domain
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Serine/threonine-protein kinase Nek6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK6 kinase domain
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Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for EIF2AK1 kinase domain
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Ribosomal protein S6 kinase alpha-6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.00E+3nM
Assay Description:
Binding constant for RSK4(Kin.Dom.1-N-terminal) kinase domain
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Serine/threonine-protein kinase LATS2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.10E+3nM
Assay Description:
Binding constant for LATS2 kinase domain
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Hormonally up-regulated neu tumor-associated kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for HUNK kinase domain
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Serine/threonine-protein kinase ULK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 450nM
Assay Description:
Binding constant for ULK2 kinase domain
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STE20-like serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 720nM
Assay Description:
Binding constant for SLK kinase domain
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Maternal embryonic leucine zipper kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.10E+3nM
Assay Description:
Binding constant for MELK kinase domain
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NUAK family SNF1-like kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.30E+3nM
Assay Description:
Binding constant for ARK5 kinase domain
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Serine/threonine-protein kinase ICK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ICK kinase domain
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Microtubule-associated serine/threonine-protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MAST1 kinase domain
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Serine/threonine-protein kinase 38-like
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for NDR2 kinase domain
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TRAF2 and NCK-interacting protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 150nM
Assay Description:
Binding constant for TNIK kinase domain
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Serine/threonine-protein kinase SIK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 400nM
Assay Description:
Binding constant for SIK2 kinase domain
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Serine/threonine-protein kinase 36
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for STK36 kinase domain
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Interleukin-1 receptor-associated kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 860nM
Assay Description:
Binding constant for IRAK4 kinase domain
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Serine/threonine-protein kinase TAO2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for TAOK2 kinase domain
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Serine/threonine-protein kinase NLK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for NLK kinase domain
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Serine/threonine-protein kinase TAO3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.20E+3nM
Assay Description:
Binding constant for TAOK3 kinase domain
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Serine/threonine-protein kinase 26
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.20E+3nM
Assay Description:
Binding constant for MST4 kinase domain
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Target
Myosin-IIIa
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MYO3A kinase domain
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Receptor-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for RIPK2 kinase domain
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Serine/threonine-protein kinase RIO3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.00E+3nM
Assay Description:
Binding constant for RIOK3 kinase domain
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Target
Serine/threonine-protein kinase PRP4 homolog
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 8.70E+3nM
Assay Description:
Binding constant for PRP4 kinase domain
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Target
Ribosomal protein S6 kinase alpha-4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA4(Kin.Dom.2-C-terminal) kinase domain
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Target
Cyclin-dependent kinase-like 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDKL2 kinase domain
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Serine/threonine-protein kinase BRSK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for BRSK2 kinase domain
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Target
Non-receptor tyrosine-protein kinase TNK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
Kd: 2.20E+3nM
Assay Description:
Binding constant for TNK1 kinase domain
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Target
Dual specificity protein kinase CLK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CLK3 kinase domain
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Target
Dual specificity protein kinase CLK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 940nM
Assay Description:
Binding constant for CLK2 kinase domain
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Target
Serine/threonine-protein kinase PLK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PLK3 kinase domain
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 78nM
Assay Description:
Binding constant for FLT3(R834Q) kinase domain
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Target
Cyclin-dependent kinase-like 1 [2-358]
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDKL1 kinase domain
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Serine/threonine-protein kinase 17B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 7.50E+3nM
Assay Description:
Binding constant for DRAK2 kinase domain
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Target
Activin receptor type-1B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 10nM
Assay Description:
Binding constant for ACVR1B kinase domain
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Target
ALK tyrosine kinase receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 840nM
Assay Description:
Binding constant for ALK kinase domain
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Bone morphogenetic protein receptor type-1A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for BMPR1A kinase domain
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Serine/threonine-protein kinase B-raf
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for BRAF(V600E) kinase domain
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Target
Tyrosine-protein kinase CSK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CSK kinase domain
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Target
Casein kinase I isoform gamma-3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1G3 kinase domain
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Target
Ephrin type-A receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 6.10E+3nM
Assay Description:
Binding constant for EPHA2 kinase domain
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Ephrin type-A receptor 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 7.70E+3nM
Assay Description:
Binding constant for EPHA4 kinase domain
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Ephrin type-A receptor 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 6.70E+3nM
Assay Description:
Binding constant for EPHA7 kinase domain
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Target
Ephrin type-B receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.50E+3nM
Assay Description:
Binding constant for EPHB1 kinase domain
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Target
Ephrin type-B receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHB3 kinase domain
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Target
Ephrin type-B receptor 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.70E+3nM
Assay Description:
Binding constant for EPHB4 kinase domain
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Target
Ephrin type-B receptor 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.10E+3nM
Assay Description:
Binding constant for EPHB6 kinase domain
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Target
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3C2G kinase domain
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Target
Mitogen-activated protein kinase kinase kinase kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 65nM
Assay Description:
Binding constant for MAP4K2 kinase domain
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Target
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 440nM
Assay Description:
Binding constant for RSK2(Kin.Dom.1-N-terminal) kinase domain
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.10E+3nM
Assay Description:
Binding constant for TGFBR1 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 8.00E+3nM
Assay Description:
Binding constant for ASK2 kinase domain
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Target
Serine/threonine-protein kinase LATS1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.30E+3nM
Assay Description:
Binding constant for LATS1 kinase domain
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Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for DYRK1B kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 13
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 210nM
Assay Description:
Binding constant for LZK kinase domain
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Target
Serine/threonine-protein kinase DCLK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 8.30E+3nM
Assay Description:
Binding constant for DCAMKL1 kinase domain
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Target
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA5(Kin.Dom.2-C-terminal) kinase domain
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Target
Cyclin-dependent kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK5 kinase domain
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Target
Serine/threonine-protein kinase mTOR
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MTOR kinase domain
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Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 9.90nM
Assay Description:
Binding constant for JAK2(JH1domain-catalytic) kinase domain
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CD kinase domain
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Target
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PLK1 kinase domain
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Target
cAMP-dependent protein kinase catalytic subunit PRKX
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKX kinase domain
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Target
Serine/threonine-protein kinase OSR1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for OSR1 kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 340nM
Assay Description:
Binding constant for ABL1(Q252H)-nonphosphorylated kinase domain
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Target
Tyrosine-protein kinase ABL2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 5.30E+3nM
Assay Description:
Binding constant for ABL2 kinase domain
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Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for AKT1 kinase domain
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Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.20nM
Assay Description:
Binding constant for CSF1R kinase domain
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for EGFR(S752-I759del) kinase domain
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Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 670nM
Assay Description:
Binding constant for MET kinase domain
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Phosphorylase b kinase gamma catalytic chain, liver/testis isoform
(Homo sapiens (Human))
Ambit Biosciences
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ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.70E+3nM
Assay Description:
Binding constant for PHKG2 kinase domain
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Serine/threonine-protein kinase STK11
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for LKB1 kinase domain
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Angiopoietin-1 receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for TIE2 kinase domain
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Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.10E+3nM
Assay Description:
Binding constant for IGF1R kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 15
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.50E+3nM
Assay Description:
Binding constant for MAP3K15 kinase domain
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Target
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.70E+3nM
Assay Description:
Binding constant for PIM3 kinase domain
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Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CHEK2 kinase domain
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ERBB2 kinase domain
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Target
Ribosomal protein S6 kinase alpha-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for RSK3(Kin.Dom.1-N-terminal) kinase domain
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Target
Activated CDC42 kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 870nM
Assay Description:
Binding constant for TNK2 kinase domain
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 56nM
Assay Description:
Binding constant for TRKA kinase domain
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Target
Myosin light chain kinase family member 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 870nM
Assay Description:
Binding constant for MYLK4 kinase domain
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Target
Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.50E+3nM
Assay Description:
Binding constant for PAK4 kinase domain
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Serine/threonine-protein kinase SBK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.10E+3nM
Assay Description:
Binding constant for SBK1 kinase domain
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Target
Serine/threonine-protein kinase DCLK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for DCAMKL2 kinase domain
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Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ERBB4 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 370nM
Assay Description:
Binding constant for HPK1 kinase domain
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Serine/threonine-protein kinase ULK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 900nM
Assay Description:
Binding constant for ULK3 kinase domain
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Target
Focal adhesion kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.70E+3nM
Assay Description:
Binding constant for FAK kinase domain
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Target
Calcium/calmodulin-dependent protein kinase type II subunit gamma
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2G kinase domain
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Target
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 760nM
Assay Description:
Binding constant for PYK2 kinase domain
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Target
Serine/threonine-protein kinase SIK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.00E+3nM
Assay Description:
Binding constant for SIK kinase domain
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Target
Serine/threonine-protein kinase 32C
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for YANK3 kinase domain
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Target
Ankyrin repeat and protein kinase domain-containing protein 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.40E+3nM
Assay Description:
Binding constant for ANKK1 kinase domain
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Target
Ephrin type-A receptor 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 5.50E+3nM
Assay Description:
Binding constant for EPHA5 kinase domain
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Target
Myosin light chain kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 42nM
Assay Description:
Binding constant for MLCK kinase domain
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Target
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PKMYT1 kinase domain
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Target
G protein-coupled receptor kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.20E+3nM
Assay Description:
Binding constant for GRK4 kinase domain
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Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 190nM
Assay Description:
Binding constant for LRRK2 kinase domain
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Target
Serine/threonine-protein kinase Nek5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK5 kinase domain
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Target
Leukocyte tyrosine kinase receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for LTK kinase domain
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Target
Tyrosine-protein kinase ZAP-70
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ZAP70 kinase domain
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Target
Serine/threonine-protein kinase N1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.40E+3nM
Assay Description:
Binding constant for PKN1 kinase domain
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Target
Wee1-like protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for WEE2 kinase domain
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Target
Uncharacterized serine/threonine-protein kinase SBK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.10E+3nM
Assay Description:
Binding constant for SgK110 kinase domain
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Target
Dual serine/threonine and tyrosine protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 740nM
Assay Description:
Binding constant for RIPK5 kinase domain
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Target
Calcium-dependent protein kinase 1
(Plasmodium Falciparum)
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PFCDPK1(P.falciparum) kinase domain
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Target
Activin receptor type-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 390nM
Assay Description:
Binding constant for ACVR1 kinase domain
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Target
Activin receptor type-2B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVR2B kinase domain
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Target
Serine/threonine-protein kinase 32A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for YANK1 kinase domain
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Target
Cyclin-dependent kinase-like 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDKL3 kinase domain
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Target
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MKNK1 kinase domain
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Target
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 590nM
Assay Description:
Binding constant for PIP5K1A kinase domain
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Target
Bone morphogenetic protein receptor type-1B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 370nM
Assay Description:
Binding constant for BMPR1B kinase domain
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Target
Bone morphogenetic protein receptor type-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 310nM
Assay Description:
Binding constant for BMPR2 kinase domain
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Target
Cyclin-dependent kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK3 kinase domain
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Target
Cyclin-dependent kinase 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK8 kinase domain
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Target
Cyclin-dependent kinase 9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK9 kinase domain
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Target
Casein kinase I isoform gamma-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1G2 kinase domain
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Target
Death-associated protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 4.70E+3nM
Assay Description:
Binding constant for DAPK3 kinase domain
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Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 5.70E+3nM
Assay Description:
Binding constant for ERN1 kinase domain
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Target
Inhibitor of nuclear factor kappa-B kinase subunit beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for IKK-beta kinase domain
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Target
Interleukin-1 receptor-associated kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 220nM
Assay Description:
Binding constant for IRAK1 kinase domain
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Target
Activin receptor type-2A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVR2A kinase domain
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Target
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for AKT2 kinase domain
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Target
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 5.30nM
Assay Description:
Binding constant for AXL kinase domain
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Target
Tyrosine-protein kinase Blk
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 11nM
Assay Description:
Binding constant for BLK kinase domain
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Target
Cytoplasmic tyrosine-protein kinase BMX
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 780nM
Assay Description:
Binding constant for BMX kinase domain
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Target
Calcium/calmodulin-dependent protein kinase type IV
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK4 kinase domain
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Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK2 kinase domain
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Target
Cyclin-dependent kinase 7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK7 kinase domain
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Target
Casein kinase I isoform alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1A1 kinase domain
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Target
Casein kinase I isoform epsilon
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1E kinase domain
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Target
Casein kinase II subunit alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK2A1 kinase domain
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Target
Casein kinase II subunit alpha'
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 6.20E+3nM
Assay Description:
Binding constant for CSNK2A2 kinase domain
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Target
Epithelial discoidin domain-containing receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 9.40nM
Assay Description:
Binding constant for DDR1 kinase domain
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Target
Receptor tyrosine-protein kinase erbB-3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ERBB3 kinase domain
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Target
Tyrosine-protein kinase Fes/Fps
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.10E+3nM
Assay Description:
Binding constant for FES kinase domain
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Target
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 53nM
Assay Description:
Binding constant for FLT1 kinase domain
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Target
Tyrosine-protein kinase FRK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 5.50E+3nM
Assay Description:
Binding constant for FRK kinase domain
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Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 720nM
Assay Description:
Binding constant for GSK3B kinase domain
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Target
Tyrosine-protein kinase HCK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.70E+3nM
Assay Description:
Binding constant for HCK kinase domain
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Target
Tyrosine-protein kinase JAK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 200nM
Assay Description:
Binding constant for JAK1(JH1domain-catalytic) kinase domain
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Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 460nM
Assay Description:
Binding constant for VEGFR2 kinase domain
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Target
LIM domain kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for LIMK1 kinase domain
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Target
Tyrosine-protein kinase Lyn
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.60E+3nM
Assay Description:
Binding constant for LYN kinase domain
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Target
Megakaryocyte-associated tyrosine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CTK kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 220nM
Assay Description:
Binding constant for MAP3K3 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MLK3 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 10
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MLK2 kinase domain
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Target
Serine/threonine-protein kinase Nek2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK2 kinase domain
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Target
Serine/threonine-protein kinase Nek3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK3 kinase domain
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Target
Serine/threonine-protein kinase PAK 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK1 kinase domain
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Target
Serine/threonine-protein kinase PAK 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK2 kinase domain
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Target
Serine/threonine-protein kinase PAK 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 370nM
Assay Description:
Binding constant for PAK3 kinase domain
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Target
Cyclin-dependent kinase 18 [3-474]
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PCTK3 kinase domain
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Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 28nM
Assay Description:
Binding constant for PDGFRB kinase domain
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Target
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.90E+3nM
Assay Description:
Binding constant for PDPK1 kinase domain
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Target
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3C2B kinase domain
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Target
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.30E+3nM
Assay Description:
Binding constant for PIM1 kinase domain
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CG kinase domain
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Target
Phosphatidylinositol 4-kinase beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK4CB kinase domain
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Target
cAMP-dependent protein kinase catalytic subunit alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PKAC-alpha kinase domain
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Target
cAMP-dependent protein kinase catalytic subunit beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PKAC-beta kinase domain
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Target
Serine/threonine-protein kinase D1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 420nM
Assay Description:
Binding constant for PRKD1 kinase domain
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Target
Mitogen-activated protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK1 kinase domain
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Target
Mitogen-activated protein kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK4 kinase domain
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Target
Mitogen-activated protein kinase 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK3 kinase domain
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Target
Mitogen-activated protein kinase 7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK5 kinase domain
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Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 830nM
Assay Description:
Binding constant for JNK1 kinase domain
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Target
Mitogen-activated protein kinase 11
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for p38-beta kinase domain
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Target
Mitogen-activated protein kinase 10
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 240nM
Assay Description:
Binding constant for JNK3 kinase domain
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Target
Mitogen-activated protein kinase 13
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for p38-delta kinase domain
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Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
Kd: 200nM
Assay Description:
Binding constant for MEK1 kinase domain
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Target
Dual specificity mitogen-activated protein kinase kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Affinity Data
Kd: 360nM
Assay Description:
Binding constant for MEK3 kinase domain
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Dual specificity mitogen-activated protein kinase kinase 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.20E+3nM
Assay Description:
Binding constant for MEK6 kinase domain
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Target
Interferon-induced, double-stranded RNA-activated protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKR kinase domain
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Target
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for RAF1 kinase domain
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Target
Rhodopsin kinase GRK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.70E+3nM
Assay Description:
Binding constant for GRK1 kinase domain
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Proto-oncogene tyrosine-protein kinase ROS
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 4.50E+3nM
Assay Description:
Binding constant for ROS1 kinase domain
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Target
Dual specificity mitogen-activated protein kinase kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.40E+3nM
Assay Description:
Binding constant for MEK4 kinase domain
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Target
SRSF protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.70E+3nM
Assay Description:
Binding constant for SRPK1 kinase domain
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Serine/threonine-protein kinase Nek4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK4 kinase domain
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Cyclin-dependent kinase-like 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDKL5 kinase domain
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Target
Ephrin type-A receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.60E+3nM
Assay Description:
Binding constant for EPHA3 kinase domain
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Target
Tyrosine-protein kinase Fer
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 120nM
Assay Description:
Binding constant for FER kinase domain
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Target
Tyrosine-protein kinase Fgr
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 220nM
Assay Description:
Binding constant for FGR kinase domain
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Target
Cyclin-G-associated kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 870nM
Assay Description:
Binding constant for GAK kinase domain
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Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 180nM
Assay Description:
Binding constant for LCK kinase domain
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Target
Protein kinase C epsilon type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCE kinase domain
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Target
Rho-associated protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ROCK1 kinase domain
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Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.40E+3nM
Assay Description:
Binding constant for SRC kinase domain
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Target
Tyrosine-protein kinase receptor Tie-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for TIE1 kinase domain
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Target
Tyrosine-protein kinase Yes
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 430nM
Assay Description:
Binding constant for YES kinase domain
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Target
RAC-gamma serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for AKT3 kinase domain
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Target
Homeodomain-interacting protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 4.00E+3nM
Assay Description:
Binding constant for HIPK3 kinase domain
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Target
Serine/threonine-protein kinase D3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 480nM
Assay Description:
Binding constant for PRKD3 kinase domain
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Target
Serine/threonine-protein kinase MAK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MAK kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP3K1 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ASK1 kinase domain
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Target
Protein-tyrosine kinase 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for BRK kinase domain
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Target
Serine/threonine-protein kinase 10
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.70E+3nM
Assay Description:
Binding constant for LOK kinase domain
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Target
Serine/threonine-protein kinase MRCK beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MRCKB kinase domain
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Target
BDNF/NT-3 growth factors receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 120nM
Assay Description:
Binding constant for TRKB kinase domain
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Target
Tyrosine-protein kinase ITK/TSK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 490nM
Assay Description:
Binding constant for ITK kinase domain
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Target
LIM domain kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for LIMK2 kinase domain
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Target
Muscle, skeletal receptor tyrosine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 5.60E+3nM
Assay Description:
Binding constant for MUSK kinase domain
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Target
Serine/threonine-protein kinase Nek11
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK11 kinase domain
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Target
Homeodomain-interacting protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for HIPK1 kinase domain
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Target
Tyrosine-protein kinase Fyn
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 340nM
Assay Description:
Binding constant for FYN kinase domain
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Target
Serine/threonine-protein kinase NIM1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for NIM1 kinase domain
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Target
Protein kinase C iota type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCI kinase domain
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Target
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.10E+3nM
Assay Description:
Binding constant for RSK1(Kin.Dom.1-N-terminal) kinase domain
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Target
Serine/threonine-protein kinase ULK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.90E+3nM
Assay Description:
Binding constant for ULK1 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 360nM
Assay Description:
Binding constant for MAP4K5 kinase domain
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NCI pathway
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Target
Death-associated protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.40E+3nM
Assay Description:
Binding constant for DAPK2 kinase domain
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Cyclin-dependent kinase 19
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK11 kinase domain
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Target
Ribosomal protein S6 kinase beta-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for S6K1 kinase domain
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Tyrosine-protein kinase SYK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 9.00E+3nM
Assay Description:
Binding constant for SYK kinase domain
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Tyrosine-protein kinase Tec
(Homo sapiens (Human))
Ambit Biosciences
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ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.00E+3nM
Assay Description:
Binding constant for TEC kinase domain
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TGF-beta receptor type-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.00E+3nM
Assay Description:
Binding constant for TGFBR2 kinase domain
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Dual specificity protein kinase TTK
(Homo sapiens (Human))
Ambit Biosciences
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ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 34nM
Assay Description:
Binding constant for TTK kinase domain
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Tyrosine-protein kinase TXK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 1.10E+3nM
Assay Description:
Binding constant for TXK kinase domain
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Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human))
Ambit Biosciences
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ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 5.80nM
Assay Description:
Binding constant for TYK2(JH1domain-catalytic) kinase domain
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Target
Wee1-like protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for WEE1 kinase domain
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Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 3.70E+3nM
Assay Description:
Binding constant for PIP5K2B kinase domain
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Serine/threonine-protein kinase 24
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 2.10E+3nM
Assay Description:
Binding constant for MST3 kinase domain
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Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for DYRK2 kinase domain
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Aurora kinase A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for AURKA kinase domain
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Serine/threonine-protein kinase MRCK alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MRCKA kinase domain
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Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 210nM
Assay Description:
Binding constant for MAP4K3 kinase domain
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Calcium/calmodulin-dependent protein kinase type 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK1 kinase domain
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MAP kinase-activated protein kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MAPKAPK5 kinase domain
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Peripheral plasma membrane protein CASK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CASK kinase domain
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Cyclin-dependent kinase 13
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CDC2L5 kinase domain
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Receptor-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50355499
(CHEMBL1908395 | CHEMBL1908842)
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Kd: 240nM
Assay Description:
Binding constant for RIPK1 kinase domain
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