Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetG1/S-specific cyclin-D1(Homo sapiens (Human))
Cyclacel

LigandBDBM59097(Aminopyrimidine, 10)Copy SMILESCopy InChI

Affinity DataIC50:  7nMAssay Description:In vitro kinase inhibition assay.More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University Of Tours

Curated by ChEMBL

LigandBDBM59097(Aminopyrimidine, 10)Copy SMILESCopy InChI

Affinity DataIC50:  219nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetG1/S-specific cyclin-E1(Homo sapiens (Human))
Cyclacel

LigandBDBM59097(Aminopyrimidine, 10)Copy SMILESCopy InChI

Affinity DataIC50:  220nMAssay Description:In vitro kinase inhibition assay.More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI