Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCalcium release-activated calcium channel protein 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL

LigandBDBM50204536(CHEMBL3984105)Copy SMILESCopy InChI

Affinity DataIC50:  26nMAssay Description:Inhibition of Orai1 (unknown origin) by patch clamp assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCalcium release-activated calcium channel protein 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL

LigandBDBM50204536(CHEMBL3984105)Copy SMILESCopy InChI

Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI