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Found 2 Enz. Inhib. hit(s) with Target = 'Calcium release-activated calcium channel protein 1' and Ligand = 'BDBM50204536'
TargetCalcium release-activated calcium channel protein 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50204536(CHEMBL3984105)
Affinity DataIC50:  26nMAssay Description:Inhibition of Orai1 (unknown origin) by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium release-activated calcium channel protein 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50204536(CHEMBL3984105)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed