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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50:  32nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50:  32nMAssay Description:Inhibition of ALK-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50:  46nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 4(Mus musculus)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50:  152nMAssay Description:Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50:  9.83E+3nMAssay Description:Inhibition of ALK6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed