Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
942
hits in this display
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3nM
Assay Description:
Inhibition of EGFR (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.70E+3nM
Assay Description:
Time dependent inhibition of CYP3A4 in human liver microsomes assessed as quasi-irreversible complex formation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Cytochrome P450 3A5
(Homo sapiens (Human))
National University Of Singapore
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.76E+4nM
Assay Description:
Inhibition of human recombinant CYP3A5 using testosterone as substrate assessed as testosterone 6-beta-hydroxylation preincubated up to 30 mins with ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.0600nM
Assay Description:
Inhibition of human N-terminal GST-tagged EGFR (669 to 1210 residues) expressed in baculovirus infected Sf9 insect cells using TK as substrate preinc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.200nM
Assay Description:
Inhibition of human N-terminal GST-tagged EGFR L858R mutant (669 to 1210 residues) expressed in baculovirus infected Sf9 insect cells using TK as sub...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.80nM
Assay Description:
Inhibition of probe binding to EGFR L858R mutant (unknown origin) using rabbit reticulate lysate system after 1 hr by luminescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.70nM
Assay Description:
Inhibition of HER2 (unknown origin) assessed as reduction in autophosphorylation by ELISA method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.80nM
Assay Description:
Inhibition of C-terminal His6-tagged HER2 (703 to 1029 residues) (unknown origin) expressed in Sf9 insect cells using TK as substrate preincubated fo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.90nM
Assay Description:
Inhibition of EGFR by flash plate based radioactive enzyme assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Inhibition of wild type EGFR (unknown origin) in presence of radiolabelled gammaATP by radioisotope filter binding assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Inhibition of HER2 by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
pH: 7.5
Assay Description:
The EGFR, HER2 and HER4 kinase assay were performed using radiolabeled [gamma-32P] ATP from GE Healthcare.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.07nM
Assay Description:
EGFR: The compounds' inhibition of target modulation were determined as follows: NCI-H838 cells were sorted in 96 well plates (20000 cells/well) ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
US Patent
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.5nM
Assay Description:
Inhibition of HER2 by flash plate based radioactive enzyme assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.5nM
Assay Description:
Inhibition of EGFR (unknown origin) by Z'-LYTE assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.60nM
Assay Description:
Assay Procedures:The abbreviations used in the following assay have the following meanings:HEPES: hydroxyethyl piperazine ethanesulfonic acid;Brij-35...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
US Patent
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Xuanzhu Pharma
US Patent
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.60nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
US Patent
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.60nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.90nM
Assay Description:
Inhibition of HER1 (unknown origin) assessed as reduction in autophosphorylation by ELISA method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8nM
Assay Description:
Inhibition of EGFR L858R mutant (unknown origin) in presence of radiolabelled gammaATP by radioisotope filter binding assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8nM
Assay Description:
Inhibition of wild-type EGFR expressed using baculovirus expression system by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.90nM
Assay Description:
Inhibition of EGFR using poly(Glu,Tyr)4:1 as substrate and [gamma33P]ATP after 60 mins by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Inhibition of human EGFR preincubated 2 hrs prior addition of ATP by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Inhibition of Her-2 by time-resolved fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Inhibition of ErbB2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Inhibition of EGFR after 50 mins by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
pH: 7.5 T: 2°C
Assay Description:
Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
pH: 7.5 T: 2°C
Assay Description:
Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP/[gamma-33P]ATP, and purified kinase in t...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Inhibition of Her-2 by time-resolved fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Inhibitory constant against Adenosine A2A receptor using [3H]-SCH-58,261 as radio ligand
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Inhibition of ErbB2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Inhibition of HER2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Inhibition of HER2 by homogeneous time-resolved fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.20nM
Assay Description:
Inhibition of HER2 (unknown origin) expressed in baculovirus infected insect cells after 20 mins in presence of ATP by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.20nM
Assay Description:
Inhibition of HER2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.20nM
Assay Description:
Inhibition of HER2 (unknown origin) in presence of radiolabelled gammaATP by radioisotope filter binding assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.80nM
Assay Description:
Inhibition of HER2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.80nM
Assay Description:
Antagonist potency against adenosine A2A receptor of Sprague-Dawley rat aortic smooth muscle
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.80nM
Assay Description:
Inhibition of HER2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of HER2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of erbB2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of EGFR by homogeneous time-resolved fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of EGFR (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of EGFR (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of EGFR (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Antagonist potency against adenosine A2B receptor of guinea pig thoracic aortic smooth muscle
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of ErbB2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of HER-2 (unknown origin) using poly-(Glu4-Tyr) as substrate after 1 hr by ELISA-based spectrophotometry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of EGFR (unknown origin) expressed in baculovirus system assessed as reduction in phosphorylation of Peptide A incubated for 10 mins by sc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of EGF-induced EGFR phosphorylation at Tyr-residue in human HN5 cells preincubated for 24 hrs followed by EGF-stimulation and measured aft...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
pH: 7.5 T: 2°C
Assay Description:
Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10.3nM
Assay Description:
Inhibition of human ErbB2 preincubated for 2 hrs prior addition of ATP by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of EGFR (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of EGFR (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of EGFR (unknown origin) expressed in baculovirus expression system using Biotin-(amino hexonoic acid)-EEEEYFELVAKKKCONH2 as substrate and...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of epidermal growth factor receptor kinase (unknown origin) using [33P]-ATP after 20 to 30 mins by radiometric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of EGFR (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of wild type human N-terminal GST-tagged EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system after 1...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
pH: 7.5 T: 2°C
Assay Description:
Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP/[gamma-33P]ATP, and purified kinase in t...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of EGFR (unknown origin) after 40 mins by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of EGFR (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
Inhibition of ErbB1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of HER2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition measured after 40 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
pH: 7.5
Assay Description:
The EGFR, HER2 and HER4 kinase assay were performed using radiolabeled [gamma-32P] ATP from GE Healthcare.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of exogenous EGFR (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15nM
Assay Description:
Inhibition of EGFR (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 16nM
Assay Description:
Inhibition of EGFR (unknown origin) using poly-(Glu4-Tyr) as substrate after 1 hr by ELISA-based spectrophotometry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 16nM
Assay Description:
Samples:Controls: Gefitinib, erlotinib hydrochloride, purchased from Anqing worldchem Co., LTD.; lapatinib ditosylate, purchased from Taizhou Xingche...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
US Patent
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 17nM
Assay Description:
Inhibition of human recombinant EGFR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 17nM
Assay Description:
Inhibition of His-tagged human HER2 (676 to 1255 residues) expressed in baculovirus after 1 hr by Z-lyte assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 19nM
Assay Description:
Inhibition of EGFR by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 21nM
Assay Description:
Inhibition of EGFR in human A431 cells assessed as reduction in EGF-stimulated EGFR autophosphorylation preincuabted for 90 mins followed by EGF-stim...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 22nM
Assay Description:
Inhibition of EGFR (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition measured after 40 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23.1nM
Assay Description:
HER2: The compounds' inhibition of target modulation were determined as follows: BT474 cells were sorted in 96 well plates (20000 cells/well) wit...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 24nM
Assay Description:
Inhibition of HER2 (unknown origin) assessed as remaining ATP level measured after 15 mins by luminescence analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 24nM
Assay Description:
Inhibition of human N-terminal GST-tagged EGFR L858R/T790M mutant (669 to 1210 residues) expressed in baculovirus infected Sf9 insect cells using TK ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 26nM
Assay Description:
Inhibition of GST-tagged wild type recombinant human EGFR (668 to 1210 residues) expressed in baculovirus after 1 hr by Z-lyte assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27nM
Assay Description:
Inhibition of recombinant EGFR (unknown origin) using by ELISA assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27nM
Assay Description:
Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27nM
Assay Description:
Inhibition of EGFR in human HepG2 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27nM
Assay Description:
Inhibition of recombinant human N-terminal His-tagged EGFR (1 to 645 residues) expressed in HEK293 cells by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27nM
Assay Description:
Inhibition of recombinant human C-terminal His-tagged EGFR (1 to 645 residues) expressed in HEK293 cells by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27nM
Assay Description:
Inhibition of wild type recombinant EGFR (unknown origin) by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 28nM
Assay Description:
Inhibition of EGFR (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 29nM
Assay Description:
Inhibition of HER2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <32nM
Assay Description:
Inhibition of EGF-induced EGFR phopshorylation in human CAL27 cells overexpressing EGFR after 16 hrs by Western blot
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 33nM
Assay Description:
Inhibition of wild type human N-terminal His-tagged HER2 cytoplasmic domain (676 to 1255 residues) expressed in baculovirus expression system after 1...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 36nM
Assay Description:
Inhibition of Her2 by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 36.3nM
Assay Description:
Inhibition of HER2 preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 38nM
Assay Description:
Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition and...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 42nM
Assay Description:
Inhibition of HER2 (unknown origin) by ADP-Glo assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 46nM
Assay Description:
Inhibition of EGFR (unknown origin) by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 52nM
Assay Description:
Inhibition of Her1 by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 52nM
Assay Description:
Inhibition of EGFR intracellular phosphorylation in human A431 cells by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 52.2nM
Assay Description:
Inhibition of wild-type EGFR preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 60nM
Assay Description:
Inhibition of Erbb2 using poly(Glu,Tyr)4:1 as substrate and [gamma33P]ATP after 60 mins by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 60nM
Assay Description:
Inhibition of His-tagged human recombinant Her2 (676 to 1255 residues) expressed in baculovirus by fluorescence based assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 62nM
Assay Description:
Inhibition of EGFR in human KB cells assessed as reduction in EGF-stimulated EGFR phosphorylation preincubated for 1 hr followed by EGF stimulation a...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 96nM
Assay Description:
Inhibition of HER2 (unknown origin) in presence of substrate incubated for 30 mins by ADP-Glo assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 100nM
Assay Description:
Inhibition of ErbB2 by time resolved fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 124nM
Assay Description:
Inhibition of HER2 in human SKBR3 cells by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 140nM
Assay Description:
Inhibition of ERBb2 phosphorylation in human MIAPaCa cells by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 140nM
Assay Description:
Inhibition of EGFR in human A431 cells by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Xuanzhu Pharma
US Patent
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 190nM
Assay Description:
Inhibition of ErbB4 in human T47D cells assessed as suppression of neuregulin 1-induced autophosphorylation incubated for 90 mins by sandwich ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 225nM
Assay Description:
Inhibition of N-terminal GST-tagged recombinant human EGFR T790M mutant expressed in baculovirus infected Sf21 insect cells preincubated for 5 mins f...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Xuanzhu Pharma
US Patent
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 250nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
US Patent
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 280nM
Assay Description:
Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Xuanzhu Pharma
US Patent
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 347nM
pH: 7.5
Assay Description:
The EGFR, HER2 and HER4 kinase assay were performed using radiolabeled [gamma-32P] ATP from GE Healthcare.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Xuanzhu Pharma
US Patent
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 367nM
pH: 7.5 T: 2°C
Assay Description:
Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP/[gamma-33P]ATP, and purified kinase in t...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Xuanzhu Pharma
US Patent
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 387nM
Assay Description:
Inhibition of HER4 (unknown origin) in presence of radiolabelled gammaATP by radioisotope filter binding assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 433nM
Assay Description:
Inhibition of EGFR phosphorylation in human MIAPaCa cells by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 540nM
Assay Description:
Inhibition of His-tagged human HER-2 cytoplasmic domain (676-1245 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometr...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibition of fast sodium current (INa) in HEK293 cells transfected with human Nav1.5 measured using IonWorks Quattro automated patch clamp platform
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Xuanzhu Pharma
US Patent
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+3nM
Assay Description:
Inhibition of HER4 preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+3nM
Assay Description:
Inhibition of human N-terminal GST-tagged EGFR cytoplasmic domain (669 to 1210 residues) T790M mutant expressed in baculovirus expression system afte...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.69E+3nM
Assay Description:
Inhibiton of EGFR (unknown origin) expressed in human A431 cells assessed as reduction in EGFR induced cell viability after 96 hrs by CellTiter-Glo a...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Broad substrate specificity ATP-binding cassette transporter ABCG2
(Homo sapiens (Human))
Federal University Of Parana
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.20E+3nM
Assay Description:
Inhibition of ABCG2 (unknown origin) expressed in human MCF7 cells membrane mediated [125I]iodoarylazidoprazosin photolabelling for 5 mins followed b...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >4.00E+3nM
Assay Description:
Inhibition of EGFR L858R/T790M mutant (unknown origin) in presence of radiolabelled gammaATP by radioisotope filter binding assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.49E+3nM
Assay Description:
Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.50E+3nM
Assay Description:
Inhibition of human BSEP expressed in HEK293 cell membrane vesicles assessed as reduction in 3H-TCA uptake incubated for 5 mins by radiodetection met...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.50E+3nM
Assay Description:
Ability to inhibit the binding of [125I]RT155 to Serotonin transporter in HEK cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.50E+3nM
Assay Description:
Inhibitory activity against human thymidine phosphorylase
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.50E+3nM
Assay Description:
Inhibition of PDGFRbeta by flash plate based radioactive enzyme assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <1.00E+4nM
Assay Description:
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 3
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of Flag tagged human recombinant HDAC3 expressed in Sf21 cells coexpressing SMRT DAD domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of Flag tagged human recombinant HDAC8 expressed in Sf21 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant HDAC6 expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of VEGFR2 using poly(Glu,Tyr)4:1 as substrate and [gamma33P]ATP after 60 mins by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant HDAC1 expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant IGF1R expressed in Sf21 cells by time resolved fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10E+4nM
Assay Description:
Inhibition of CDK2 by flash plate based radioactive enzyme assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.48E+4nM
Assay Description:
Inhibiton of EGFR L858R/T790M mutant (unknown origin) expressed in human NCI-H1975 cells assessed as reduction in EGFR induced cell viability after 9...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Insulin receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70E+4nM
Assay Description:
Inhibition of INSR by flash plate based radioactive enzyme assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
Palack£
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of recombinant human N-terminal GST-His6 tagged PDGFRalpha (Q551 to L1089 residues) expressed in Sf9 insect cells using poly(Ala,Glu,Lys,T...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1
(Homo sapiens (Human))
Palack£
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.30E+4nM
Assay Description:
Inhibition of ABL1 by flash plate based radioactive enzyme assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of IGF1R phosphorylation in human MIAPaCa cells by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.11E+4nM
Assay Description:
Inhibition of EGFR L858R mutant (unknown origin) by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of PLK1 by flash plate based radioactive enzyme assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+5nM
Assay Description:
Inhibition of KDR (unknown origin) by ELISA method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+5nM
Assay Description:
Inhibition of PDGFRbeta (unknown origin) by ELISA method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+5nM
Assay Description:
Inhibition of c-KIT (unknown origin) by ELISA method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily E/KQT member 1
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.51E+5nM
Assay Description:
Inhibition of slow delayed inward rectifying potassium current (Iks) in Chinese Hamster Ovary (CHO) cells expressing hKvLQT1/hminK measured using Ion...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.77E+5nM
Assay Description:
Inhibition of EGFR T790M mutant (unknown origin) by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.31E+5nM
Assay Description:
Inhibition of rapid delayed inward rectifying potassium current (IKr) in Chinese hamster ovary (CHO) cells stable expressing hERG measured using IonW...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.00E+6nM
Assay Description:
Inhibition of long-lasting type calcium current (hICa) in Chinese Hamster Ovary (CHO) cells expressing hCav1.2 measured using IonWorks Quattro automa...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.16E+6nM
Assay Description:
Inhibition of rapid delayed inward rectifying potassium current (IKr) in Chinese hamster ovary (CHO) K1 cells stably expressing hERG measured using I...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.58E+7nM
Assay Description:
Inhibition of fast sodium current (INa) in HEK293 cells transfected with human Nav1.5 measured using IonWorks Quattro automated patch clamp platform
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+8nM
Assay Description:
Inhibition of fast sodium current (INa) in HEK293 cells transfected with human Nav1.5 measured using IonWorks Quattro automated patch clamp platform
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor [G719C]
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 0.920nM
pH: 7.4 T: 2°C
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PCBioAssay
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 8.60nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PCBioAssay
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor [1-999,L858R]
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.80E+3nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PCBioAssay
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.60E+3nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 4.20nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PCBioAssay
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 7nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.40nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PCBioAssay
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.10nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PCBioAssay
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.20nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PCBioAssay
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.90nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PCBioAssay
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.5nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PCBioAssay
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.20nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PCBioAssay
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3(D835Y) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RSK3(Kin.Dom.1-N-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C eta type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCH kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(D816V) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TYK2(JH2domain-pseudokinase) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(F317I)-phosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.20nM
Assay Description:
Binding constant for EGFR(L747-E749del, A750P) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Serine/threonine-protein kinase MRCK gamma
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DMPK2 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1-nonphosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(F317L)-phosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Death-associated protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DAPK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase TNNI3K
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TNNI3K kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.10nM
Assay Description:
Binding constant for EGFR(G719S) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(F317L)-nonphosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myosin-IIIb
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MYO3B kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3(D835H) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MARK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA5(Kin.Dom.1-N-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
AP2-associated protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AAK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(I800L) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(V559D,V654A) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(H396P)-phosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myotonin-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DMPK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(T315I)-nonphosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1-phosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Inhibitor of nuclear factor kappa-B kinase subunit alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for IKK-alpha kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RSK4(Kin.Dom.2-C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.20nM
Assay Description:
Binding constant for EGFR(L861Q) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MET(M1250T) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-dependent protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKG1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 8.60nM
Assay Description:
Binding constant for EGFR(E746-A750del) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3(ITD) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RET(V804L) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.40nM
Assay Description:
Binding constant for EGFR kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK4-cyclinD3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(T315I)-phosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EGFR(L858R,T790M) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3(N841I) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(V559D,T670I) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(M1043I) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Misshapen-like kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MINK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP3K4 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(M351T)-phosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA6 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 17A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DRAK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase BRSK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BRSK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(E545K) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 11A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDC2L2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JAK1(JH1domain-catalytic) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RET kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(V559D) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(Q252H)-nonphosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(Q546K) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.80nM
Assay Description:
Binding constant for EGFR(L858R) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Interleukin-1 receptor-associated kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for IRAK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RSK1(Kin.Dom.1-N-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
eIF-2-alpha kinase GCN2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for GCN2(Kin.Dom.2,S808G) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(E255K)-phosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(C420R) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for INSR kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CHEK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BRAF kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3(K663Q) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMKK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.90nM
Assay Description:
Binding constant for EGFR(L747-S752del, P753S) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 0.920nM
Assay Description:
Binding constant for EGFR(G719C) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LRRK2(G2019S) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(E545A) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
SRSF protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SRPK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase D2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKD2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myosin light chain kinase, smooth muscle
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MYLK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Rho-associated protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ROCK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type II subunit alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2A kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type II subunit beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2B kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Macrophage-stimulating protein receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MST1R kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(Q252H)-phosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(A829P) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MET kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(H1047Y) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.5nM
Assay Description:
Binding constant for EGFR(L747-T751del,Sins) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(H396P)-nonphosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA4(Kin.Dom.2-C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(E542K) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(L576P) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(F317I)-nonphosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR3(G697C) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 4.20nM
Assay Description:
Binding constant for EGFR(S752-I759del) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RET(V804M) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AURKB kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glycogen synthase kinase-3 alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length GSK3A
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.5nM
Assay Description:
Binding constant for EGFR(L747-T751del,Sins) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(E255K) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-dependent protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKG1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C eta type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCH kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA4(Kin.Dom.2 - N-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3(N841I) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 4.20nM
Assay Description:
Binding constant for EGFR(S752-I759del) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.80nM
Assay Description:
Binding constant for EGFR(L858R) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 0.920nM
Assay Description:
Binding constant for EGFR(G719C) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA6(Kin.Dom.1 - C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(V559D,V654A) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(H396P) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Death-associated protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length DLK
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RET(M918T) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myotonin-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DMPK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CHEK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interleukin-1 receptor-associated kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for IRAK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(Q252H) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.40nM
Assay Description:
Binding constant for EGFR kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.10nM
Assay Description:
Binding constant for EGFR(G719S) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 8.60nM
Assay Description:
Binding constant for EGFR(E746-A750del) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Aurora kinase B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AURKB kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BRAF(V600E) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(D816V) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA1(Kin.Dom.1 - N-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR3(G697C) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3(D835H) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(M351T) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA2(Kin.Dom.1 - N-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.20nM
Assay Description:
Binding constant for EGFR(L747-E749del, A750P) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.90nM
Assay Description:
Binding constant for EGFR(L747-S752del, P753S) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(Y253F) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase D2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKD2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA5(Kin.Dom.1 - C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(V559D) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3(D835Y) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 10
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.60E+3nM
Assay Description:
Average Binding Constant for STK10; NA=Not Active at 10 uM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 5.5nM
Assay Description:
Average Binding Constant for EGFR; NA=Not Active at 10 uM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 11nM
Assay Description:
Average Binding Constant for ERBB2; NA=Not Active at 10 uM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
STE20-like serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 9.30E+3nM
Assay Description:
Average Binding Constant for SLK; NA=Not Active at 10 uM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase mTOR
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MTOR kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PLK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PLK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIM2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Citron Rho-interacting kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CIT kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 38
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NDR1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase tousled-like 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TLK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 14
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PFTK1 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIP5K1C kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
STE20/SPS1-related proline-alanine-rich protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for STK39 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TBK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Sgk3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SGK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for IKK-epsilon kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin receptor-related protein
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for INSRR kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PLK4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PLK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Death-associated protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DAPK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
SRSF protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SRPK3 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK6 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EIF2AK1 kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RSK4(Kin.Dom.1-N-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase LATS2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LATS2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Hormonally up-regulated neu tumor-associated kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for HUNK kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase ULK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ULK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
STE20-like serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.30E+3nM
Assay Description:
Binding constant for SLK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Maternal embryonic leucine zipper kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MELK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
NUAK family SNF1-like kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ARK5 kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase ICK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ICK kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Microtubule-associated serine/threonine-protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAST1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 38-like
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NDR2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
TRAF2 and NCK-interacting protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TNIK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 19
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK11 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase SIK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SIK2 kinase domain
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 36
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for STK36 kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interleukin-1 receptor-associated kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for IRAK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase TAO2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TAOK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase NLK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NLK kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase TAO3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TAOK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 26
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MST4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myosin-IIIa
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MYO3A kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-B receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHB2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase MARK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MARK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP kinase-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MKNK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
BMP-2-inducible protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BIKE kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transient receptor potential cation channel subfamily M member 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TRPM6 kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
SNF-related serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SNRK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase RIO2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RIOK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 32B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for YANK2 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase MARK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MARK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glycogen synthase kinase-3 alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for GSK3A kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK6 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Atypical kinase COQ8A, mitochondrial
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ADCK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK7 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type 1D
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK1D kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type 1G
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK1G kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA8 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RET(M918T) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-interacting serine/threonine-protein kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RIPK4 kinase domain
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CLK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase TAO1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TAOK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase I isoform gamma-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1G1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Homeodomain-interacting protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for HIPK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIP5K2C kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Atypical kinase COQ8B, mitochondrial
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ADCK4 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 19
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for YSK4 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MEK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 33
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for STK33 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
NUAK family SNF1-like kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SNARK kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP/microtubule affinity-regulating kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MARK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase RIO1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RIOK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Testis-specific serine/threonine-protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TSSK1B kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMKK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAPKAPK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK9 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myosin light chain kinase 2, skeletal/cardiac muscle
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MYLK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MLK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase DCLK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DCAMKL3 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis)
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PKNB(M.tuberculosis) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 11B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDC2L1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Srms
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SRMS kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 35
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for STK35 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DYRK1A kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK7 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 20
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ZAK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for p38-alpha kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 15
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK8 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase I isoform delta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1D kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JNK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 15
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PFTAIRE2 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Rhodopsin kinase GRK7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for GRK7 kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Homeodomain-interacting protein kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for HIPK4 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.10E+3nM
Assay Description:
Binding constant for MEK5 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 4.40E+3nM
Assay Description:
Binding constant for MKK7 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase I isoform alpha-like
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1A1L kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TAK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP4K4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek11
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK11 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Homeodomain-interacting protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for HIPK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Fyn
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FYN kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase NIM1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NIM1 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Focal adhesion kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FAK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type II subunit gamma
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2G kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PYK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase SIK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SIK kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 32C
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for YANK3 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ankyrin repeat and protein kinase domain-containing protein 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ANKK1 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA5 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myosin light chain kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MLCK kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PKMYT1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
G protein-coupled receptor kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for GRK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LRRK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK5 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Leukocyte tyrosine kinase receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LTK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ZAP-70
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ZAP70 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase N1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PKN1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Wee1-like protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for WEE2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Uncharacterized serine/threonine-protein kinase SBK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SgK110 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual serine/threonine and tyrosine protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RIPK5 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium-dependent protein kinase 1
(Plasmodium Falciparum)
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PFCDPK1(P.falciparum) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 2 homolog
(Plasmodium falciparum (isolate 3D7))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PFPK5(P.falciparum) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AKT2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AXL kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Blk
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BLK kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytoplasmic tyrosine-protein kinase BMX
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BMX kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type IV
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK7 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase I isoform alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1A1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase I isoform epsilon
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1E kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase II subunit alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK2A1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase II subunit alpha'
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK2A2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epithelial discoidin domain-containing receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DDR1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 5.50E+3nM
Assay Description:
Binding constant for ERBB3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Fes/Fps
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FES kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase FRK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FRK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for GSK3B kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase HCK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for HCK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JAK1(JH2domain-pseudokinase) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for VEGFR2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
LIM domain kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LIMK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lyn
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LYN kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Megakaryocyte-associated tyrosine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CTK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP3K3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MLK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 10
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MLK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK3 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 18 [3-474]
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PCTK3 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PDGFRB kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PDPK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 670nM
Assay Description:
Binding constant for PIK3C2B kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIM1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CG kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4-kinase beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 940nM
Assay Description:
Binding constant for PIK4CB kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cAMP-dependent protein kinase catalytic subunit alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PKAC-alpha kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cAMP-dependent protein kinase catalytic subunit beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PKAC-beta kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C iota type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCI kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase D1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKD1 kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK4 kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK5 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JNK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 11
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for p38-beta kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 10
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JNK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 13
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for p38-delta kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MEK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MEK3 kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MEK6 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interferon-induced, double-stranded RNA-activated protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKR kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RAF1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Rhodopsin kinase GRK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for GRK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase ROS
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ROS1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RSK1(Kin.Dom.2-C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MEK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
SRSF protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SRPK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK4 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase-like 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDKL5 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase beta-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for S6K1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase SYK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SYK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Tec
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TEC kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
TGF-beta receptor type-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TGFBR2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase TTK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TTK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase TXK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TXK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TYK2(JH1domain-catalytic) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Wee1-like protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for WEE1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIP5K2B kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase ULK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ULK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 24
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MST3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DYRK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AURKA kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase MRCK alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MRCKA kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP4K3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP kinase-activated protein kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAPKAPK5 kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Peripheral plasma membrane protein CASK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CASK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 13
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDC2L5 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RIPK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.60E+3nM
Assay Description:
Binding constant for RIPK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase RIO3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RIOK3 kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PRP4 homolog
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRP4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase-like 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDKL2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase BRSK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BRSK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Non-receptor tyrosine-protein kinase TNK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TNK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CLK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CLK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PLK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PLK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3(R834Q) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase-like 1 [2-358]
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDKL1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 17B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DRAK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Activin receptor type-1B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVR1B kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ALK tyrosine kinase receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ALK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bone morphogenetic protein receptor type-1A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BMPR1A kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BRAF(V600E) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase CSK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase I isoform gamma-3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1G3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA7 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-B receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHB1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-B receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHB3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-B receptor 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHB4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-B receptor 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHB6 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 7.50E+3nM
Assay Description:
Binding constant for PIK3C2G kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RSK2(Kin.Dom.1-N-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TGFBR1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ASK2 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase LATS1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LATS1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DYRK1B kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 13
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LZK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase DCLK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DCAMKL1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA5(Kin.Dom.2-C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK5 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JAK2(JH1domain-catalytic) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CD kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PLK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cAMP-dependent protein kinase catalytic subunit PRKX
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKX kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase OSR1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for OSR1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(Y253F)-phosphorylated kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AKT1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSF1R kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA(H1047L) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CB kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AMPK-alpha2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C delta type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCD kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase N2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PKN2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C theta type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCQ kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-dependent protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKG2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MST2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MST1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity testis-specific protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TESK1 kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TYRO3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase VRK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for VRK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 12
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DLK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 25
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for YSK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP4K5 kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP3K2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 860nM
Assay Description:
Binding constant for EGFR kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Ephrin type-A receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Fer
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FER kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Fgr
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGR kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-G-associated kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for GAK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LCK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C epsilon type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCE kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Rho-associated protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ROCK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SRC kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CLK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
NT-3 growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TRKC kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Mer
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MERTK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase C
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AURKC kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type II subunit delta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2D kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase tousled-like 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TLK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5'-AMP-activated protein kinase catalytic subunit alpha-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AMPK-alpha1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase SIK3 [59-1321]
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for QSK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 16
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for STK16 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase receptor Tie-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TIE1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Yes
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for YES kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAC-gamma serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AKT3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ITK/TSK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ITK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
LIM domain kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LIMK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscle, skeletal receptor tyrosine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MUSK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Homeodomain-interacting protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for HIPK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase D3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKD3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase MAK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAK kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP3K1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ASK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein-tyrosine kinase 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BRK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 10
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 4.40E+3nM
Assay Description:
Binding constant for LOK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase MRCK beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MRCKB kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
BDNF/NT-3 growth factors receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TRKB kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 16
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PCTK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
Palack£
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PDGFRA kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PHKG1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MET(M1250T) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PHKG2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase STK11
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LKB1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Angiopoietin-1 receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TIE2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for IGF1R kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 15
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP3K15 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIM3 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CHEK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 7nM
Assay Description:
Binding constant for ERBB2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RSK3(Kin.Dom.1-N-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA4(Kin.Dom.2-C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Activated CDC42 kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TNK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TRKA kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myosin light chain kinase family member 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MYLK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase SBK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SBK1 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase DCLK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DCAMKL2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Xuanzhu Pharma
US Patent
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 54nM
Assay Description:
Binding constant for ERBB4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for HPK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase ULK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ULK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Activin receptor type-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVR1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Activin receptor type-2B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVR2B kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 32A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for YANK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase-like 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDKL3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MKNK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIP5K1A kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bone morphogenetic protein receptor type-1B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BMPR1B kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bone morphogenetic protein receptor type-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BMPR2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK8 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK9 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase I isoform gamma-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1G2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Death-associated protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DAPK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ERN1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Inhibitor of nuclear factor kappa-B kinase subunit beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for IKK-beta kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interleukin-1 receptor-associated kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for IRAK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Activin receptor type-2A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVR2A kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP4K2 kinase domain
More data for this Ligand-Target Pair
Target Info
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 12
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for p38-gamma kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 17
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PCTK2 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Discoidin domain-containing receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DDR2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase receptor R3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVRL1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase BTK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BTK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK4-cyclinD1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JAK3(JH1domain-catalytic) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(D816H) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA4(Kin.Dom.1 - C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epithelial discoidin domain-containing receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DDR1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase FRK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FRK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
AP2-associated protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AAK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(T315I) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length NEK7
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ankyrin repeat and protein kinase domain-containing protein 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ANKK1 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PLK4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PLK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Discoidin domain-containing receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DDR2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase SIK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length SNF1LK2
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CDK9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AMPK-alpha2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP4K4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP4K5 kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase MRCK beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MRCKB kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CDK7
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
NUAK family SNF1-like kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SNARK kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 17B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length DRAK2
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK5 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA5 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA6 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type II subunit alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2A kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase MARK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MARK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP/microtubule affinity-regulating kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MARK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Citron Rho-interacting kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CIT kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ITK/TSK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ITK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JAK1(Kin.Dom.1/JH2 - pseudokinase) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase SIK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SNF1LK kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SRC kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP3K4 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA7 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ABL2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 11B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDC2L1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 32B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length YANK2
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C theta type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCQ kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Leukocyte tyrosine kinase receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LTK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lyn
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LYN kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIM1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myosin-IIIa
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MYO3A kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myosin-IIIb
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MYO3B kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP3K5 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK6 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Activin receptor type-2A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVR2A kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 11
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length p38-beta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSF1R kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-B receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHB2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Fyn
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FYN kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase II subunit alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSNK2A1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase II subunit alpha'
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSNK2A2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MST1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BRAF kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MEK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase RIO1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length RIOK1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CAMK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CDK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CDK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MARK3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 19
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK11 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin receptor-related protein
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for INSRR kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for INSR kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Activin receptor type-2B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVR2B kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cAMP-dependent protein kinase catalytic subunit alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PKAC-alpha kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PIP5K2B
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Atypical kinase COQ8B, mitochondrial
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length ADCK4
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase C
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length AURKC
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytoplasmic tyrosine-protein kinase BMX
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length BMX
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 26
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MST4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3(ITD) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase receptor Tie-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TIE1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MST2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase tousled-like 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TLK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length DYRK1B
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length ERK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myosin light chain kinase, smooth muscle
(Gallus gallus (chicken))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MLCK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMKK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK4 kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MLK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 10
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MLK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase MRCK alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MRCKA kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase BRSK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BRSK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase RIO3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length RIOK3
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 24
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MST3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Non-receptor tyrosine-protein kinase TNK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length TNK1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Angiopoietin-1 receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TIE2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAPKAPK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RAF1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(V559D,T670I) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PIP5K1A
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK5 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 16
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for STK16 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Death-associated protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DAPK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase DCLK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DCAMKL1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 32C
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for YANK3 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
STE20-like serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SLK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TYRO3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase receptor R3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVRL1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP4K1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA5(Kin.Dom.1 - C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cAMP-dependent protein kinase catalytic subunit PRKX
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PRKX
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PTK2B
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscle, skeletal receptor tyrosine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MUSK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cAMP-dependent protein kinase catalytic subunit beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PKAC-beta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myosin light chain kinase, smooth muscle
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MYLK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase tousled-like 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TLK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase I isoform epsilon
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSNK1E
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
TRAF2 and NCK-interacting protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TNIK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase I isoform delta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSNK1D
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JAK2(Kin.Dom.2/JH1 - catalytic) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Fes/Fps
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FES kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TYK2(Kin.Dom.2/JH1 - catalytic) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TRKA kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-B receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHB3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type 1D
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK1D kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type 1G
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK1G kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LCK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myosin light chain kinase 2, skeletal/cardiac muscle
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MYLK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TGFBR1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA8 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
SRSF protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length SRPK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 18 [3-474]
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PCTK3
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JAK3(Kin.Dom.2/JH1 - catalytic) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase MRCK gamma
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DMPK2 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase I isoform gamma-3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSNK1G3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIM2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIM3 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase DCLK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DCAMKL3 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 38-like
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NDR2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myosin light chain kinase family member 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SgK085 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Srms
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SRMS kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
BDNF/NT-3 growth factors receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TRKB kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AXL kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 10
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 4.40E+3nM
Assay Description:
Binding constant for LOK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP4K3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-B receptor 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHB4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 7nM
Assay Description:
Binding constant for ERBB2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 33
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length STK33
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
TGF-beta receptor type-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TGFBR2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
SRSF protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length SRPK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Fer
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FER kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase D1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKD1 kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-G-associated kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for GAK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PAK3
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PDPK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase CSK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSK
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA6(Kin.Dom.2 - N-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase LATS1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LATS1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
BMP-2-inducible protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BIKE kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MLK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
NT-3 growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TRKC kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Activin receptor type-1B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVR1B kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Death-associated protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length DAPK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tubulin alpha-1A chain
(Rattus norvegicus)
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 54nM
Assay Description:
Binding constant for ERBB4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase BRSK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length BRSK2
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase BTK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length BTK
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase TNNI3K
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length TNNI3K
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Testis-specific serine/threonine-protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length TSSK1
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PHKG2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase I isoform alpha-like
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSNK1A1L
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 12
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length p38-gamma
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cGMP-dependent protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKG2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MET kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 20
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ZAK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase TTK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TTK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDK8 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type II subunit beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2B kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK6 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Maternal embryonic leucine zipper kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MELK
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MKNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 14
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PFTK1
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PHKG1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type II subunit gamma
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2G kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 36
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for STK36 kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase SYK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SYK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Tec
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TEC kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for VEGFR2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Wee1-like protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for WEE1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Blk
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BLK kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bone morphogenetic protein receptor type-1A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BMPR1A kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Nek9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK9 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CLK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PKMYT1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase N1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PKN1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase N2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PKN2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 17
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PCTK2
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Atypical kinase COQ8A, mitochondrial
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ADCK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 15
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK8 kinase domain
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interferon-induced, double-stranded RNA-activated protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKR kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Death-associated protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DAPK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity testis-specific protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TESK1 kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Activin receptor type-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVR1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AKT1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AKT2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAC-gamma serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AKT3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CLK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bone morphogenetic protein receptor type-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BMPR2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glycogen synthase kinase-3 alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length GSK3A
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length GSK3B
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length IKK-epsilon
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
LIM domain kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length LIMK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA2(Kin.Dom.2 - C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase NLK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length NLK
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP kinase-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MKNK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase STK11
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length LKB1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Focal adhesion kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PTK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein-tyrosine kinase 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PTK6 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C delta type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCD kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP kinase-activated protein kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAPKAPK5 kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase MARK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MARK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
NUAK family SNF1-like kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ARK5 kinase domain
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Yes
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for YES kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 25
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for YSK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Activated CDC42 kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TNK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA1(Kin.Dom.2 - C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Fgr
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGR kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CLK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase DCLK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DCAMKL2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RET kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length p38-alpha
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length ERK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PLK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PLK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PLK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C epsilon type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCE kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CLK3
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type IV
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMKK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Mer
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MERTK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
eIF-2-alpha kinase GCN2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for GCN2(Kin.Dom.2,S808G) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MEK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MEK3
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase I isoform gamma-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSNK1G2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase HCK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for HCK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for IGF1R kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MEK4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calcium/calmodulin-dependent protein kinase type II subunit delta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2D kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AURKA kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
Palack£
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PDGFRA kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PDGFRB kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase I isoform gamma-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1G1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA4 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK7/PAK5 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ZAP-70
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ZAP70 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-B receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHB1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RIPK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CDK5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase D3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKD3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase 17A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DRAK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 10
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JNK3 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length JNK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
LIM domain kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length LIMK1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.20nM
Assay Description:
Binding constant for EGFR(L861Q) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
ALK tyrosine kinase receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ALK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5'-AMP-activated protein kinase catalytic subunit alpha-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AMPK-alpha1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 16
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PCTK1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MEK6 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.60E+3nM
Assay Description:
Binding constant for RIPK2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase ROS
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ROS1 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase LATS2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LATS2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase TXK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TXK kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 11A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDC2L2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA3(Kin.Dom.1 - N-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Southeast University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding affinity to human KIT incubated for 1 hr by kinase binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 11nM
Assay Description:
Binding affinity to wild-type human partial length EGFR (R669 to V1011 residues) expressed in bacterial expression system by Kinomescan method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.80nM
Assay Description:
Inhibition of recombinant human partial length EGFR L858R mutant (669 to 1011 residues) expressed in bacterial expression system by competitive bindi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Xuanzhu Pharma
US Patent
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 54nM
Assay Description:
Inhibition of recombinant human wild type partial length HER4 (690 to 994 residues) expressed in bacterial expression system by competitive binding a...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
ATP-dependent translocase ABCB1
(Homo sapiens (Human))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >2.79E+3nM
Assay Description:
Inhibition of P-gp (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Broad substrate specificity ATP-binding cassette transporter ABCG2
(Homo sapiens (Human))
Federal University Of Parana
Curated by
ChEMBL
Ligand
BDBM5445
(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.20E+3nM
Assay Description:
Inhibition of BCRP (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Displayed 1 to 50 (of 942 total ) |
Next
|
Last
>>