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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Collagenase 3
(Homo sapiens (Human))
Alantos Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50386430
(CHEMBL2047536)
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Affinity Data
IC50: 0.0300nM
Assay Description:
Inhibition of human recombinant MMP13 using MCA-Pro-Cha-Gly-Nva-His-Ala-Dpa-NH2 as substrate preincubated for 10 mins measured by fluorescence analys...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
Alantos Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50386430
(CHEMBL2047536)
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Affinity Data
IC50: 0.0300nM
Assay Description:
Inhibition of MMP-13 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
In Depth
Details
PubMed
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Target
Macrophage metalloelastase
(Homo sapiens (Human))
Alantos Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50386430
(CHEMBL2047536)
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Affinity Data
IC50: 655nM
Assay Description:
Inhibition of human recombinant MMP12 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence a...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
A disintegrin and metalloproteinase with thrombospondin motifs 4
(Homo sapiens (Human))
Alantos Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50386430
(CHEMBL2047536)
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Affinity Data
IC50: 2.40E+3nM
Assay Description:
Inhibition of human recombinant aggrecanase 1 using aggrecan-IGD as substrate measured after 15 mins by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Neutrophil collagenase
(Homo sapiens (Human))
Alantos Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50386430
(CHEMBL2047536)
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Affinity Data
IC50: 3.20E+3nM
Assay Description:
Inhibition of human recombinant MMP8 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Stromelysin-1
(Homo sapiens (Human))
Alantos Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50386430
(CHEMBL2047536)
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Affinity Data
IC50: 8.20E+3nM
Assay Description:
Inhibition of human recombinant MMP3 using MCAArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(DNP)-NH2 as substrate preincubated for 10 mins measured by fluo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Alantos Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50386430
(CHEMBL2047536)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of human recombinant MMP9 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Alantos Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50386430
(CHEMBL2047536)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of human recombinant MMP2 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrilysin
(Homo sapiens (Human))
Alantos Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50386430
(CHEMBL2047536)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of human recombinant MMP7 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Alantos Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50386430
(CHEMBL2047536)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of human recombinant MMP14 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence a...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Alantos Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50386430
(CHEMBL2047536)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of human recombinant TACE using MCA-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH2 as substrate preincubated for 10 mins measured by ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Alantos Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50386430
(CHEMBL2047536)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of human recombinant MMP1 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI