Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Integrin alpha-4/beta-1
(Homo sapiens (Human))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50117069
((S)-2-(2-Chloro-6-methyl-benzoylamino)-3-[4-(2,6-d...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.300nM
Assay Description:
Inhibitory binding concentration against VCAM/VLA-4 in ELISA.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-4/beta-1
(Homo sapiens (Human))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50117069
((S)-2-(2-Chloro-6-methyl-benzoylamino)-3-[4-(2,6-d...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of human VCAM1 binding to integrin alpha4beta1 receptor in human Ramos cells labeled with Calcein AM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-4/beta-1
(Homo sapiens (Human))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50117069
((S)-2-(2-Chloro-6-methyl-benzoylamino)-3-[4-(2,6-d...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of human VCAM1 binding to integrin alpha4beta1 receptor in human Ramos cells labeled with Calcein AM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-4/beta-1
(Homo sapiens (Human))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50117069
((S)-2-(2-Chloro-6-methyl-benzoylamino)-3-[4-(2,6-d...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
Inhibitory binding concentration against VCAM/VLA-4 in Ramos.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-4/beta-7
(Homo sapiens (Human))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50117069
((S)-2-(2-Chloro-6-methyl-benzoylamino)-3-[4-(2,6-d...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 43nM
Assay Description:
Inhibition of human MAdCAM1 binding to integrin alpha4beta7 receptor in human RPMI 8866 cells labeled with Calcein AM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-4/beta-7
(Homo sapiens (Human))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50117069
((S)-2-(2-Chloro-6-methyl-benzoylamino)-3-[4-(2,6-d...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 43nM
Assay Description:
Inhibition of human MAdCAM1 binding to integrin alpha4beta7 receptor in human RPMI 8866 cells labeled with Calcein AM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-2/beta-1
(Homo sapiens (Human))
Sanofi R & D
Curated by
ChEMBL
Ligand
BDBM50117069
((S)-2-(2-Chloro-6-methyl-benzoylamino)-3-[4-(2,6-d...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 214nM
Assay Description:
Antagonist activity at recombinant integrin alpha2 beta1 receptor (unknown origin) assessed as inhibition of interaction with biotinylated collagen t...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI