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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig))
Universit£T M£Nster
Curated by
ChEMBL
Ligand
BDBM50252686
(CHEMBL4077148)
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Affinity Data
Ki: 0.570nM
Assay Description:
Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by microbeta scintillation counting method
More data for this Ligand-Target Pair
Target Info
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Article
PubMed
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Target
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig))
Universit£T M£Nster
Curated by
ChEMBL
Ligand
BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
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Affinity Data
Ki: 0.590nM
Assay Description:
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human))
The University Of Sydney
Curated by
ChEMBL
Ligand
BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
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Affinity Data
Ki: 0.590nM
Assay Description:
Binding affinity to sigma 1 receptor by radioligand displacement assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig))
Universit£T M£Nster
Curated by
ChEMBL
Ligand
BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.590nM
Assay Description:
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vesicular acetylcholine transporter
(Homo sapiens (Human))
Institute Of Radiopharmacy
Curated by
ChEMBL
Ligand
BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
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Affinity Data
Ki: 1.40nM
Assay Description:
Binding affinity to VAChT
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig))
Universit£T M£Nster
Curated by
ChEMBL
Ligand
BDBM50252685
(CHEMBL4064375)
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Affinity Data
Ki: 2.30nM
Assay Description:
Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by microbeta scintillation counting method
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Vesicular acetylcholine transporter
(Homo sapiens (Human))
Institute Of Radiopharmacy
Curated by
ChEMBL
Ligand
BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
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Affinity Data
Ki: 211nM
Assay Description:
Binding affinity to VAChT (unknown origin)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
(Homo sapiens (Human))
Institute Of Radiopharmacy
Curated by
ChEMBL
Ligand
BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
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Affinity Data
Ki: 211nM
Assay Description:
Binding affinity to EBP
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
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Target
Kappa-type opioid receptor
(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster
Curated by
ChEMBL
Ligand
BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
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Affinity Data
Ki: 372nM
Assay Description:
Displacement of radioligand from kappa opioid receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Kappa-type opioid receptor
(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster
Curated by
ChEMBL
Ligand
BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
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Affinity Data
Ki: 372nM
Assay Description:
Binding affinity to kappa opioid receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Mu-type opioid receptor
(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster
Curated by
ChEMBL
Ligand
BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
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Affinity Data
Ki: 456nM
Assay Description:
Displacement of radioligand from mu opioid receptor
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Mu-type opioid receptor
(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster
Curated by
ChEMBL
Ligand
BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 456nM
Assay Description:
Binding affinity to mu opioid receptor
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Homo sapiens (Human))
Institute Of Radiopharmacy
Curated by
ChEMBL
Ligand
BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Binding affinity to delta opioid receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Emopamil-binding protein-like
(Homo sapiens (Human))
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by
ChEMBL
Ligand
BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
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Affinity Data
Ki: 1.40E+3nM
Assay Description:
Binding affinity to emopamil binding protein (unknown origin)
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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