Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50587104(CHEMBL5069975 | US20240043470, Compound 2-02-B)
Affinity DataIC50:  6.75E+3nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50587104(CHEMBL5069975 | US20240043470, Compound 2-02-B)
Affinity DataIC50: >1.00E+5nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50587104(CHEMBL5069975 | US20240043470, Compound 2-02-B)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5c subunit using Suc-LLVY-AMC as substrate measured over 1.5 to 2 hrs by plate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50587104(CHEMBL5069975 | US20240043470, Compound 2-02-B)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate measured over 1.5 to 2 hrs by plate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed