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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
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Target
Short transient receptor potential channel 1
(Homo sapiens)
Universit£
Curated by
ChEMBL
Ligand
BDBM50450630
(CHEMBL101896)
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Affinity Data
IC50: 300nM
Assay Description:
Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated ...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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MCE
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Calcium release-activated calcium channel protein 1
(Rattus norvegicus)
University Of Nebraska Medical Center
Curated by
ChEMBL
Ligand
BDBM50450630
(CHEMBL101896)
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Affinity Data
IC50: 490nM
Assay Description:
Inhibition of ORAI/STIM1 in thapsigargin treated rat RBL2H3 cells assessed as reduction in store-operated calcium entry after 5 mins by fura-2-AM dye...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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MCE
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Short transient receptor potential channel 3
(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by
ChEMBL
Ligand
BDBM50450630
(CHEMBL101896)
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Copy InChI
Affinity Data
IC50: 1.85E+4nM
Assay Description:
Inhibition of YFP-tagged TRPC3 (unknown origin) expressed in HEK293 cells assessed as reduction carbhocol-induced receptor operated Calcium influx af...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI