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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 14 hits in this display   

TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant DAGLalpha overexpressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant DAGLbeta overexpressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50:  2.24E+3nMAssay Description:Inhibition of rat histidine tagged FAAH expressed in Escherichia coli by coumarin ester substrate fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of human C-terminal HA-tagged DAGLalpha expressed in HEK293F cell membrane fractions using PNP butyrate as substrate by colorimetric surro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of human C-terminal HA-tagged DAGLalpha expressed in HEK293F cell membrane fractions using PNP butyrate as substrate by colorimetric surro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral cholesterol ester hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant KIAA1363 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of recombinant PLA2g7 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylserine lipase ABHD16A(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of recombinant BAT5 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of human C-terminal HA-tagged DAGLalpha expressed in HEK293F cell membrane fractions using DiFMU-octanoate as substrate by fluorogenic sur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of human C-terminal HA-tagged DAGLalpha expressed in HEK293F cell membrane fractions using DiFMU-octanoate as substrate by fluorogenic sur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of human DAGLalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of recombinant FAAH transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIP1, secretory lipase (Family 3)(Malassezia globosa (strain ATCC MYA-4612 / CBS 796...)
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50:  7.53E+4nMAssay Description:Inhibition of Malassezia globosa CBS 7966 LIP1 using pNPA substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidylserine lipase ABHD12(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant ABHD12 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed