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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Diacylglycerol lipase-alpha
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50240877
(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
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Affinity Data
IC50: 60nM
Assay Description:
Inhibition of human recombinant DAGLalpha overexpressed in african green monkey COS7 cells
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
Diacylglycerol lipase-beta
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50240877
(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
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Affinity Data
IC50: 60nM
Assay Description:
Inhibition of human recombinant DAGLbeta overexpressed in african green monkey COS7 cells
More data for this Ligand-Target Pair
Target Info
NCI pathway
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KEGG
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Target
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat))
Northeastern University
Curated by
ChEMBL
Ligand
BDBM50240877
(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
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Affinity Data
IC50: 2.24E+3nM
Assay Description:
Inhibition of rat histidine tagged FAAH expressed in Escherichia coli by coumarin ester substrate fluorescence assay
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Target Info
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MMDB
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Target
Diacylglycerol lipase-alpha
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50240877
(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.01E+3nM
Assay Description:
Inhibition of human C-terminal HA-tagged DAGLalpha expressed in HEK293F cell membrane fractions using PNP butyrate as substrate by colorimetric surro...
More data for this Ligand-Target Pair
Target Info
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KEGG
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GoogleScholar
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CHEMBL
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Target
Diacylglycerol lipase-alpha
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50240877
(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.01E+3nM
Assay Description:
Inhibition of human C-terminal HA-tagged DAGLalpha expressed in HEK293F cell membrane fractions using PNP butyrate as substrate by colorimetric surro...
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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CHEMBL
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Target
Neutral cholesterol ester hydrolase 1
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50240877
(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
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Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibition of recombinant KIAA1363 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probe
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Target
Platelet-activating factor acetylhydrolase
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50240877
(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
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Affinity Data
IC50: 1.10E+4nM
Assay Description:
Inhibition of recombinant PLA2g7 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probe
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Phosphatidylserine lipase ABHD16A
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50240877
(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
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Affinity Data
IC50: 2.30E+4nM
Assay Description:
Inhibition of recombinant BAT5 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probe
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Target Info
KEGG
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Target
Diacylglycerol lipase-alpha
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50240877
(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.51E+4nM
Assay Description:
Inhibition of human C-terminal HA-tagged DAGLalpha expressed in HEK293F cell membrane fractions using DiFMU-octanoate as substrate by fluorogenic sur...
More data for this Ligand-Target Pair
Target Info
NCI pathway
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KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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CHEMBL
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PC sid
In Depth
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Article
PubMed
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Target
Diacylglycerol lipase-alpha
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50240877
(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.51E+4nM
Assay Description:
Inhibition of human C-terminal HA-tagged DAGLalpha expressed in HEK293F cell membrane fractions using DiFMU-octanoate as substrate by fluorogenic sur...
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
In Depth
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Article
PubMed
Copy BDB DOI
Target
Diacylglycerol lipase-alpha
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50240877
(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.50E+4nM
Assay Description:
Inhibition of human DAGLalpha
More data for this Ligand-Target Pair
Target Info
NCI pathway
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KEGG
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CHEMBL
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PC sid
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Article
PubMed
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Target
Fatty-acid amide hydrolase 1
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50240877
(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.00E+4nM
Assay Description:
Inhibition of recombinant FAAH transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probe
More data for this Ligand-Target Pair
Target Info
PDB
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Target
LIP1, secretory lipase (Family 3)
(Malassezia globosa (strain ATCC MYA-4612 / CBS 796...)
South China University Of Technology
Curated by
ChEMBL
Ligand
BDBM50240877
(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
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Affinity Data
IC50: 7.53E+4nM
Assay Description:
Inhibition of Malassezia globosa CBS 7966 LIP1 using pNPA substrate
More data for this Ligand-Target Pair
Target Info
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Target
Lysophosphatidylserine lipase ABHD12
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50240877
(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of recombinant ABHD12 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probe
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
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antibodypedia
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CHEMBL
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