Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCasein kinase II subunit alpha [2-329](Homo sapiens (Human))
Cambridge Enterprise

US Patent

LigandBDBM644508(5-(3-(4-((3- (cyanomethyl)- 5-(trifluoro- methyl) ...)Copy SMILESCopy InChI

Affinity DataIC50:  0.453nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7....More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Cambridge Enterprise

US Patent

LigandBDBM644508(5-(3-(4-((3- (cyanomethyl)- 5-(trifluoro- methyl) ...)Copy SMILESCopy InChI

Affinity DataIC50:  232nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI