Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCasein kinase II subunit alpha [2-329](Homo sapiens (Human))
Cambridge Enterprise

US Patent

LigandBDBM644517(5-(2-(4-((3- bromo-4- (trifluoro- methoxy) benzyl)...)Copy SMILESCopy InChI

Affinity DataIC50:  0.411nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7....More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Cambridge Enterprise

US Patent

LigandBDBM644517(5-(2-(4-((3- bromo-4- (trifluoro- methoxy) benzyl)...)Copy SMILESCopy InChI

Affinity DataIC50:  172nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI