Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Neutrophil collagenase
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50128648
(1-Benzyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
Assay Description:
Inhibition of Matrix metalloprotease-8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50128648
(1-Benzyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
Assay Description:
In vitro inhibitory activity against matrix metalloprotease-13.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50128648
(1-Benzyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
Assay Description:
Inhibition of Matrix metalloprotease-2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50128648
(1-Benzyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
Assay Description:
In vitro inhibitory activity against matrix metalloprotease-9.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50128648
(1-Benzyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7nM
Assay Description:
Inhibition of Matrix metalloprotease-14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50128648
(1-Benzyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 55nM
Assay Description:
Inhibition of Matrix metalloprotease-3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50128648
(1-Benzyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 301nM
Assay Description:
In vitro inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by
ChEMBL
Ligand
BDBM50128648
(1-Benzyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 420nM
Assay Description:
Inhibition of ADAMTS-5 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50128648
(1-Benzyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 801nM
Assay Description:
In vitro inhibitory activity against matrix metalloprotease-1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrilysin
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50128648
(1-Benzyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 925nM
Assay Description:
Inhibition of Matrix metalloprotease-7
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
A disintegrin and metalloproteinase with thrombospondin motifs 4
(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by
ChEMBL
Ligand
BDBM50128648
(1-Benzyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibition of ADAMTS-4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI