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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
North-West University

Curated by ChEMBL
LigandPNGBDBM50188597(CHEMBL18688)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]DPCPX from Sprague-Dawley rat whole brain membrane A1AR by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
North-West University

Curated by ChEMBL
LigandPNGBDBM50188597(CHEMBL18688)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]NECA from Sprague-Dawley rat striatal membrane A2A adenosine receptor by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Jiangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50188597(CHEMBL18688)
Affinity DataKi:  2.22E+5nMAssay Description:Mixed-type reversible inhibition of diphenolase activity of mushroom tyrosinase assessed as enzyme-substrate complex using L-DOPA as substrate by Lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Jiangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50188597(CHEMBL18688)
Affinity DataKi:  7.03E+5nMAssay Description:Mixed-type reversible inhibition of diphenolase activity of mushroom tyrosinase using L-DOPA as substrate by Lineweaver-Burk double reciprocal-plot a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50188597(CHEMBL18688)
Affinity DataIC50:  781nMAssay Description:Inhibition of TNKS-1 (unknown origin) using histone as substrate incubated for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50188597(CHEMBL18688)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells preincubated for 2 hrs followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50188597(CHEMBL18688)
Affinity DataIC50:  4.69E+3nMAssay Description:Inhibition of human PARP-2 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50188597(CHEMBL18688)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PARP-1 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Jiangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50188597(CHEMBL18688)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed