Report error Found 2729 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1'
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]9-Dimethylamino-3-(4-methoxy-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one from mGluR1 in rat cerebellum membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 0.200nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]9-Dimethylamino-3-(4-methoxy-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one from mGluR1 in rat cerebellum membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences
Curated by ChEMBL
National Institute of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Binding affinity to mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]9-Dimethylamino-3-(4-methoxy-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one from mGluR1 in rat cerebellum membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 0.400nMAssay Description:Antagonist activity at rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 0.400nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences
Curated by ChEMBL
National Institute of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Binding affinity to mGluR1 by PET analysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences
Curated by ChEMBL
National Institute of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Binding affinity to mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]9-Dimethylamino-3-(4-methoxy-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one from mGluR1 in rat cerebellum membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]9-Dimethylamino-3-(4-methoxy-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one from mGluR1 in rat cerebellum membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]9-Dimethylamino-3-(4-methoxy-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one from mGluR1 in rat cerebellum membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 0.600nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 0.700nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 0.700nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 0.870nMAssay Description:In vitro affinity for cloned rat metabotropic glutamate 1 receptors stably expressed on CHO cells determined using [3H]-R214127 as radioligandMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences
Curated by ChEMBL
National Institute of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 0.870nMAssay Description:Binding affinity to mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences
Curated by ChEMBL
National Institute of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 0.870nMAssay Description:Binding affinity to mGluR1 by PET analysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 1nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 1nMAssay Description:Displacement of [3H]9-Dimethylamino-3-(4-methoxy-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one from mGluR1 in rat cerebellum membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 1.10nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 1.10nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 1.20nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 1.5nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]9-Dimethylamino-3-(4-methoxy-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one from mGluR1 in rat cerebellum membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 1.60nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 1.90nMAssay Description:Antagonist activity at rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 1.90nMAssay Description:Antagonist activity at rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences
Curated by ChEMBL
National Institute of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity to mGluR1 by PET analysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 2nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as increase in calcium internalisation by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 2nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 2nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as increase in calcium internalisation by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 2.20nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 2.30nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]9-Dimethylamino-3-(4-methoxy-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one from mGluR1 in rat cerebellum membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 2.70nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 2.90nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 3nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 3nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as increase in calcium internalisation by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 3nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as increase in calcium internalisation by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 3.20nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 3.30nMAssay Description:Antagonist activity at rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Johnson and Johnson Pharmaceutical Research and Development, Beerse
Curated by PDSP Ki Database
Affinity DataKi: 3.5nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
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