Report error Found 474 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 4'
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
TargetP2X purinoceptor 4(Rat)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataKi: 49nMAssay Description:Competitive antagonist activity at human P2X4 receptor expressed in 1321N1 cell membrane assessed as inhibition of [35S]ATPgammaS binding by scintill...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
TargetP2X purinoceptor 4(Rat)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
TargetP2X purinoceptor 4(Rat)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
TargetP2X purinoceptor 4(Rat)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
TargetP2X purinoceptor 4(Rat)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 8nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 9nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 25nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 26nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 27nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 37nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 39nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 39nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 39nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 40nMAssay Description:Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx inc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 43nMAssay Description:Antagonist activity at human P2X4 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubate...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 44nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 45nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 49nMAssay Description:Antagonist activity at human P2X4 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubate...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 51nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 52nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 53nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 53nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 54nMAssay Description:Antagonist activity at human P2X4 receptor expressed in HEK cells assessed as reduction in ATP induced calcium influxMore data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 55nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 64nMAssay Description:The P2X4 receptor antagonist activity of the compounds of the present invention was measured as follows. The 1321N1 cells stably expressing human P2X...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 64nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influx incubated for 15 min...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 67nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 74nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 75nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
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