Report error Found 443 Enz. Inhib. hit(s) with Target = 'P2Y purinoceptor 6'
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human P2Y6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human P2Y6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human P2Y6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human P2Y6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human P2Y6 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced inositol-1-phosphate accumulation pr...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Antagonist activity at P2Y6 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human P2Y6More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Compound was tested for the contractile effects antagonized by mepyramine (1-1000 nM) against Histamine H1 receptor of guinea pig aorta.More data for this Ligand-Target Pair
TargetP2Y purinoceptor 6(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced inositol-1-phosphate accumulation prei...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human P2Y6More data for this Ligand-Target Pair
Affinity DataIC50: 155nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced inositol-1-phosphate accumulation pr...More data for this Ligand-Target Pair
Affinity DataIC50: 461nMAssay Description:Compound was tested for the agonist activity against histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 604nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization b...More data for this Ligand-Target Pair
Affinity DataIC50: 785nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization b...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+3nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+3nMAssay Description:pA2 value against Tachykinin receptor 2 in rat vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+3nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.79E+3nMAssay Description:pA2 value against Tachykinin receptor 2 in rat vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Compound was evaluated for antagonistic activity towards Tachykinin receptor 2 in rat vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 2.55E+3nMAssay Description:Antagonist activity against human P2Y6 receptor expressed in 1321N1 astrocytoma cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.57E+3nMAssay Description:Contractile effects antagonized by mepyramine (0.3-100 nM) against Histamine H1 receptor in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 2.67E+3nMAssay Description:Antagonist activity at human P2Y6 receptor transfected in human 1321N1 cells assessed as inhibition of UDP-activated intracellular calcium mobilizati...More data for this Ligand-Target Pair
Affinity DataIC50: 2.79E+3nMAssay Description:Antagonist activity at human P2Y6 receptor transfected in human 1321N1 cells assessed as inhibition of UDP-activated intracellular calcium mobilizati...More data for this Ligand-Target Pair
Affinity DataIC50: 2.91E+3nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization b...More data for this Ligand-Target Pair
Affinity DataIC50: 2.91E+3nMAssay Description:Contractile effects antagonized by mepyramine (0.3-100 nM) against Histamine H1 receptor in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 2.99E+3nMAssay Description:Compound was tested for the agonist activity against histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 3.49E+3nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization b...More data for this Ligand-Target Pair
Affinity DataIC50: 3.69E+3nMAssay Description:Compound was tested for the contractile effects antagonized by mepyramine (1-1000 nM) against Histamine H1 receptor of guinea pig aorta.More data for this Ligand-Target Pair
Affinity DataIC50: 3.92E+3nMAssay Description:Antagonist activity against human P2Y6 receptor expressed in 1321N1 astrocytoma cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.97E+3nMAssay Description:In vitro inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
Affinity DataIC50: 3.99E+3nMAssay Description:Contractile effects antagonized by mepyramine (0.3-100 nM) against Histamine H1 receptor in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Compound was tested for inhibition of cathepsin G serine protease to produce one-half maximal enzyme activity.More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization b...More data for this Ligand-Target Pair
Affinity DataIC50: 4.09E+3nMAssay Description:Compound was tested for the contractile effects antagonized by mepyramine (1-1000 nM) against Histamine H1 receptor of guinea pig aorta.More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization p...More data for this Ligand-Target Pair
TargetP2Y purinoceptor 6(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 4.34E+3nMAssay Description:Antagonist activity at rat P2Y6 receptor expressed in astrocytoma cells assessed as inhibition of intracellular calcium mobilizationMore data for this Ligand-Target Pair
TargetP2Y purinoceptor 6(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 4.34E+3nMAssay Description:Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization by ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.34E+3nMAssay Description:Antagonist activity against human P2Y6 receptor expressed in 1321N1 astrocytoma cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.36E+3nMAssay Description:Antagonist activity at human P2Y6 receptor transfected in human 1321N1 cells assessed as inhibition of UDP-activated intracellular calcium mobilizati...More data for this Ligand-Target Pair
Affinity DataIC50: 4.56E+3nMAssay Description:Antagonist activity against human P2Y6 receptor expressed in 1321N1 astrocytoma cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.65E+3nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization b...More data for this Ligand-Target Pair
Affinity DataIC50: 4.75E+3nMAssay Description:Inhibition of human Potassium channel HERG expressed in mammalian cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.77E+3nMAssay Description:Compound was tested for the agonist activity against histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 4.87E+3nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization b...More data for this Ligand-Target Pair
TargetP2Y purinoceptor 6(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 4.94E+3nMAssay Description:Functional affinity was evaluated by measuring the intracellular calcium concentration in CHO cells transfected with the human Tachykinin receptor 2 ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.22E+3nMAssay Description:Compound was tested for the agonist activity against histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 5.23E+3nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization b...More data for this Ligand-Target Pair
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