Report error Found 772 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent GABA transporter 3'
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataKi: 6.10E+3nMAssay Description:Binding affinity to GAT3More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 1.50E+4nMAssay Description:Inhibition of mouse GAT3 expressed in hamster BHK cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human GAT3 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human GAT3 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human GAT3 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of human GAT3 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of human GAT3 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of mouse GAT4 expressed in human HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 40 mins by LC-ESI-MS/MS analysi...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition mea...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cell line assessed as reduction in [3H]GABA uptake incubated for 10 minsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 35 mins by liquid scintillation metho...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of mouse GAT4 expressed in human HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 40 mins by LC-ESI-MS/MS analysi...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of human GAT3 expressed in COS-7 cells assessed as reduction in [2H6]GABA uptake preincubated for 25 mins followed by [2H6]GABA addition a...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 35 mins by liquid scintillation metho...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cell line assessed as reduction in [3H]GABA uptake incubated for 10 minsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of mouse GTA4 receptorMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition mea...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human GAT3 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition mea...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of mouse GTA4 receptorMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human GAT3 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition mea...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK cells assessed as reduction in [3H]GABA uptake by measuring remaining [3H]GABA uptake levels preincubated f...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human GAT3 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 35 mins by liquid scintillation metho...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of mouse GAT3 expressed in human HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 40 mins by LC-ESI-MS/MS analysi...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human GAT3 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human GAT3 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human GAT3 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataIC50: 2.75E+3nMAssay Description:Inhibition of human GAT3 expressed in COS7 cells assessed as reduction in [2H6]GABA uptake preincubated for 25 mins followed by [2H6]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of human GAT3 expressed in COS-7 cells assessed as reduction in [2H6]GABA uptake preincubated for 25 mins followed by [2H6]GABA addition a...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human GAT3 expressed in COS-7 cells assessed as reduction in [2H6]GABA uptake preincubated for 25 mins followed by [2H6]GABA addition a...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Zentrum F£R Pharmaforschung
Curated by ChEMBL
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of human GAT3 expressed in COS7 cells assessed as reduction in [2H6]GABA uptake preincubated for 25 mins followed by [2H6]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition mea...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cell line assessed as reduction in [3H]GABA uptake incubated for 10 minsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.63E+3nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 35 mins by liquid scintillation metho...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.63E+3nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 35 mins by liquid scintillation metho...More data for this Ligand-Target Pair
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