Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with Target = 'Transcription factor 4'
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50509813(CHEMBL4451478)
Affinity DataKi:  640nMAssay Description:Inhibition of beta catenin/Tcf4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50594243(CHEMBL5191974)
Affinity DataKi:  1.36E+3nMAssay Description:Binding affinity to beta-catenin (142 to 686 residues) (unknown origin)/C-terminal fluorescein-labeled human Tcf4 (7 to 51 residues) assessed as inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50094486(CHEMBL3589160)
Affinity DataKi:  7.60E+4nMAssay Description:Inhibition of beta catenin/Tcf4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50615368(CHEMBL5285550)
Affinity DataIC50:  16nMAssay Description:Inhibition of beta catenin/Tcf4 (unknown origin) protein protein interactionMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50500849(CHEMBL3780110)
Affinity DataIC50:  640nMAssay Description:Inhibition of human GST tagged Tcf4/beta catenin interaction after 2 hrs using fluorescent AP Attophos substrate by ELISA analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM32102(1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human GST tagged Tcf4/beta catenin interaction after 2 hrs using fluorescent AP Attophos substrate by ELISA analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50408043(CHEMBL5278981)
Affinity DataIC50:  1.50E+3nMAssay Description:Affinity for CCK2 receptor assessed by inhibition of pentagastrin-stimulated acid secretion in perfused rat stomachMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50556644(CHEMBL1214274 | NSC-45382)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of beta catenin/Tcf4 (8 to 30 reisdues) (unknown origin) incubated for 3 hrs by fluorescence polarisation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50589224(CHEMBL5173483)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of beta catenin/Tcf4 (unknown origin) protein protein interaction measured after 24 hrs by TOP-flash luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50158807(3-Butyryl-1,8-dihydroxy-2-methyl-phenanthrene-9,10...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human GST tagged Tcf4/beta catenin interaction after 2 hrs using fluorescent AP Attophos substrate by ELISA analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50468575(CHEMBL2312139)
Affinity DataIC50:  3.00E+3nMAssay Description:Affinity for CCK2 receptor assessed by inhibition of pentagastrin-stimulated acid secretion in perfused rat stomachMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50500850(CHEMBL261214)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human GST tagged Tcf4/beta catenin interaction after 2 hrs using fluorescent AP Attophos substrate by ELISA analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50590853(CHEMBL5172034)
Affinity DataIC50:  4.00E+3nMAssay Description:Binding affinity to FITC-labeled Tcf4 (unknown origin) /6His-tagged beta-catenin (135 to 668 residues) (unknown origin) protein-protein interaction a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50500848(CHEMBL2397075)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human GST tagged Tcf4/beta catenin interaction after 2 hrs using fluorescent AP Attophos substrate by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50408046(CHEMBL5284392)
Affinity DataIC50:  4.20E+3nMAssay Description:Affinity for CCK2 receptor assessed by inhibition of pentagastrin-stimulated acid secretion in perfused rat stomachMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50468575(CHEMBL2312139)
Affinity DataIC50:  4.40E+3nMAssay Description:Affinity for CCK2 receptor assessed by inhibition of pentagastrin-stimulated acid secretion in perfused rat stomachMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50590852(CHEMBL5202327)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of FITC-labeled Tcf4 (unknown origin) / full length beta-catenin (1 to 781 residues) (unknown origin) protein-protein interaction measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50589221(CHEMBL5192638)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of beta catenin/recombinant GST tagged Tcf4 protein protein interaction in human HCT-116 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50589220(CHEMBL3890384)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of beta catenin/recombinant GST tagged Tcf4 protein protein interaction in human HCT-116 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50094484(CHEBI:3556 | CHEMBL2323033 | US9284299, CGP049090 ...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of beta catenin/recombinant GST tagged Tcf4 protein protein interaction in human HCT-116 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50589363(CHEMBL5191201)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of FITC-labeled Tcf4 (unknown origin) / full length beta-catenin (1 to 781 residues) (unknown origin) protein-protein interaction measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50589362(CHEMBL5181203)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of His-tagged beta-catenin (134 to 668 residues)/CM-5 sensor chip immobilized N-terminal GST-tagged TCF4 interaction (unknown origin) prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50436058(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
Affinity DataKd:  450nMAssay Description:Affinity for CCK2 receptor assessed by inhibition of pentagastrin-stimulated acid secretion in perfused rat stomachMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscription factor 4(Homo sapiens)TBA
LigandPNGBDBM50436058(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
Affinity DataKd:  450nMAssay Description:Inhibition of His6 tagged Tcf4 1-53/beta catenin (unknown origin) interaction by VP-ITC titration calorimeter methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed