Report error Found 149 of ic50 for monomerid = 50001884
Affinity DataIC50: 1.40nMAssay Description:Inhibition of dopamine-sensitive rat brain adenylyl cyclase activity assessed as cAMP levelMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Bovine)
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by ChEMBL
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Affinity towards 5-hydroxytryptamine 2A receptor in membranes from bovine frontal cortex using [3H]-KetanserinMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Binding affinity for 5-hydroxytryptamine 2A receptor, activity is expressed as IC50 values.More data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor from rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of [3H]ketanserin binding to dopamine 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]mepyramine from H1R in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition constant against dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibition of binding of 1.0 nM [3H]-pirenzepine to cloned human Muscarinic acetylcholine receptor M1 expressed in membranes from CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibitory binding of [3H]-pirenzepine to human Muscarinic acetylcholine receptor M1 in membranes from CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by ChEMBL
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Affinity towards 5-hydroxytryptamine 2C receptor in membranes from pig choroid plexus using [3H]-N-methyl-mesulergineMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Binding affinity towards 5-HT2C receptor from rat using [3H]-mesulergine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against human 5-HT2A receptor in BEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Tested in vitro for its ability to displace 3[H] clozapine from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor from rat frontal cortex using [3H]-ketanserin as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]-ketanserin binding to rat frontal cortex membrane 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Binding affinity to dopamine receptor D4 cloned from human, using [3H]- YM09151 as competitive ligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist activity at serotonin human 5-HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced calcium flux after 15 min...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity against serotonin-2 receptor in rat brain using [3H]spiroperidolMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor in rat brain using [3H]- QNBMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium flux incubated for 60 mins at 37 d...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:The compound was tested for inhibition of [3H]WB-4101 binding to alpha-1 adrenergic receptor of rat frontal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Ability to bind at 5-hydroxytryptamine 2 receptor of rat hippocampus by displacing [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor measured using radioligand ([3H]spiperone) binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory binding of [3H]-mepyramine to histamine H1 receptors in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Binding affinity towards histamine H1 receptor from rat brain membranes using [3H]-mepyramine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Compound was measured for affinity at 5-hydroxytryptamine 2 receptor in rat cortical by [3H]spiroperidol displacement.More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity against dopamine receptor in rat striatal membrane using [3H]haloperidolMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rat)
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:In vitro binding affinity against Dopamine receptor D2 by displacement of [3H]-haloperidol from rat striatal membranes.More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Binding affinity against alpha-2 adrenergic receptor in rat brain using [3H]- clonidineMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in rat brain using [3H]- WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 40.7nMAssay Description:In vitro binding affinity for serotonin 5-hydroxytryptamine 2A receptor of rat cerebral cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Displacement of [3H]methylspiperone from human recombinant Dopamine D4.4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:The compound was tested for inhibition of [3H]QNB binding to Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Binding affinity was determined against Muscarinic acetylcholine receptor using [3H]QNB as radioligand in rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Binding activity against muscarinic receptor in rat brain using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Binding affinity towards human D4.2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibitory concentration against human Dopamine receptor D4.2 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Ability to inhibit [3H]haloperidol binding to dopamine receptor in rat striatal homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of [3H]haloperidol binding to dopamine receptors in rat striatal membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Ability to inhibit [3H]WB-4101 binding to rat cortical alpha-1-adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:In vitro inhibitory concentration against radioligand [3H]WB-4101 binding to rat cortical alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Ability to bind at Alpha-1 adrenergic receptor by displacing [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:In vitro affinity towards 5-hydroxytryptamine 2A receptor using [3H]-spiroperidol as radioligand in cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 113nMAssay Description:Binding affinity to dopamine receptor D2 cloned from human, using [3H]- YM09151 as competitive ligandMore data for this Ligand-Target Pair
Affinity DataIC50: 125nMAssay Description:Inhibition of specific [3H]-prazosin binding (0.2 nM) to rat brain membranes alpha1 adrenoceptor.More data for this Ligand-Target Pair