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Found 4 of ic50 for monomerid = 50309087
TargetIntegrin alpha-4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50309087((S)-2-((2S,4R)-1-(3-cyanophenylsulfonyl)-4-(piperi...)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50309087((S)-2-((2S,4R)-1-(3-cyanophenylsulfonyl)-4-(piperi...)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50309087((S)-2-((2S,4R)-1-(3-cyanophenylsulfonyl)-4-(piperi...)
Affinity DataIC50:  0.110nMAssay Description:Displacement of [35S]-labeled ligand from VLA4 in human Jurkat cells washed with buffer containing non activating Ca2+ and Mg2+ by competitive bindin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50309087((S)-2-((2S,4R)-1-(3-cyanophenylsulfonyl)-4-(piperi...)
Affinity DataIC50:  80nMAssay Description:Receptor occupancy of VLA4 in whole blood washed with buffer containing non activating Ca2+ and Mg2+ at 37 degC after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed