Compile Data Set for Download or QSAR
maximum 50k data
Found 6 of ic50 for monomerid = 50312933
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312933((S)-5-(2-(2-amino-3-(4-(trifluoromethyl)phenyl)pro...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human AKT1 in human U87MG cells assessed as PRAS40 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312933((S)-5-(2-(2-amino-3-(4-(trifluoromethyl)phenyl)pro...)
Affinity DataIC50:  110nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312933((S)-5-(2-(2-amino-3-(4-(trifluoromethyl)phenyl)pro...)
Affinity DataIC50:  185nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312933((S)-5-(2-(2-amino-3-(4-(trifluoromethyl)phenyl)pro...)
Affinity DataIC50:  250nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312933((S)-5-(2-(2-amino-3-(4-(trifluoromethyl)phenyl)pro...)
Affinity DataIC50:  300nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312933((S)-5-(2-(2-amino-3-(4-(trifluoromethyl)phenyl)pro...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human AKT1 in human U87MG cells assessed as PRAS40 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed