Affinity DataIC50: 0.130nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetPlasma kallikrein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of kallikreinMore data for this Ligand-Target Pair
TargetCoagulation factor XII(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of factor 12aMore data for this Ligand-Target Pair
TargetCoagulation factor XII(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human factor 12a using Z-D-Arg-Gly-Arg-pNA as substrate preincubated for 5 mins followed by substrate addition by absorbance methodMore data for this Ligand-Target Pair
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