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Found 3 of ic50 for monomerid = 50398295
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50398295(CHEMBL2177311)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of human recombinant BACE1 using Glu-Ile-Asp-Leu-Met-Val-Leu-Asp as substrate incubated for 60 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50398295(CHEMBL2177311)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50398295(CHEMBL2177311)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP Swedish mutant assessed as reduction in amyloid beta 40 production after overnight incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed