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Found 7 of ic50 for monomerid = 648235
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM648235(US11884671, Example 12)
Affinity DataIC50: <0.100nMAssay Description:The inhibitory activity of compounds against DNAPK was determined by TR-FRET measuring a fluorescent labelled peptide substrate converting to a phosp...More data for this Ligand-Target Pair
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TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM648235(US11884671, Example 12)
Affinity DataIC50:  501nMAssay Description:The inhibitory activity of compounds against TTK was determined in a LanthaScreen Eu Kinase Binding assay run by ThermoFisher Scientific as part of t...More data for this Ligand-Target Pair
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TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM648235(US11884671, Example 12)
Affinity DataIC50: >1.00E+4nMAssay Description:JAK3: The 2×JAK3/Tyr 06 (ThermoFisher Scientific proprietary) mixture was prepared in 50 mM HEPES pH 7.5. 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA. The ...More data for this Ligand-Target Pair
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TargetAurora kinase A(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM648235(US11884671, Example 12)
Affinity DataIC50: >1.00E+4nMMore data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM648235(US11884671, Example 12)
Affinity DataIC50: >1.00E+4nMAssay Description:Aurora B (AurB): The 2×AURKB (Aurora B)/Ser/Thr 01 (ThermoFisher Scientific proprietary) mixture was prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 1...More data for this Ligand-Target Pair
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TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM648235(US11884671, Example 12)
Affinity DataIC50: >1.00E+4nMAssay Description:JAK1: The 2×JAK/Tyr 06 (ThermoFisher Scientific proprietary) mixture was prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02%...More data for this Ligand-Target Pair
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TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM648235(US11884671, Example 12)
Affinity DataIC50: >1.00E+4nMAssay Description:JAK2: The 2×JAK2/Tyr 06 (ThermoFisher Scientific proprietary) mixture was prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent