Compile Data Set for Download or QSAR
maximum 50k data
Found 303 of ic50 for UniProtKB: P98170
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249163(US9453048, 4)
Affinity DataIC50:  0.220nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249162(US9453048, 3)
Affinity DataIC50:  0.460nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249168(US9453048, 10)
Affinity DataIC50:  0.480nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249161(US9453048, 2)
Affinity DataIC50:  0.490nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249169(US9453048, 11 | US9453048, 12)
Affinity DataIC50:  0.620nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249167(US9453048, 9)
Affinity DataIC50:  0.720nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243099((S)—N—((S)-5-(4-Acetylbenzoyl)-1-((6-bro...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249166(US9453048, 7)
Affinity DataIC50:  1.10nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249160(US9453048, 1)
Affinity DataIC50:  1.11nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249172(US9453048, 14)
Affinity DataIC50:  1.14nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249165(US9453048, 6)
Affinity DataIC50:  1.19nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249178(US9453048, 20)
Affinity DataIC50:  1.25nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249169(US9453048, 11 | US9453048, 12)
Affinity DataIC50:  1.70nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249164(US9453048, 5)
Affinity DataIC50:  1.84nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM412169((3S)-N-[2-[[(3S)-3-[(2,6- difluorophenyl)carbamoyl...)
Affinity DataIC50:  2nMAssay Description:For the Bir2 assay, 3.5 nanomolar of 6× Histidine-tagged BIR2 domain (6× Histidine disclosed as SEQ ID NO: 25), corresponding to amino acids 124-240 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249171(US9453048, 13 | US9453048, 15)
Affinity DataIC50:  2nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249174(US9453048, 16)
Affinity DataIC50:  2.11nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249177(US9453048, 19)
Affinity DataIC50:  2.21nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249171(US9453048, 13 | US9453048, 15)
Affinity DataIC50:  2.43nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249175(US9453048, 17)
Affinity DataIC50:  2.44nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249176(US9453048, 18)
Affinity DataIC50:  2.68nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM412170((3R)-N-[2-[[(3S)-3-[(2,6- difluorophenyl)carbamoyl...)
Affinity DataIC50:  3nMAssay Description:For the Bir2 assay, 3.5 nanomolar of 6× Histidine-tagged BIR2 domain (6× Histidine disclosed as SEQ ID NO: 25), corresponding to amino acids 124-240 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM412183(US10398702, Example 22 | tert-Butyl (2R,5S)-4-[2-[...)
Affinity DataIC50:  3nMAssay Description:For the Bir2 assay, 3.5 nanomolar of 6× Histidine-tagged BIR2 domain (6× Histidine disclosed as SEQ ID NO: 25), corresponding to amino acids 124-240 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM412173((R)-N-((S)-3-((2,6- difluorophenyl)carbamoyl)- 2-(...)
Affinity DataIC50:  3nMAssay Description:For the Bir2 assay, 3.5 nanomolar of 6× Histidine-tagged BIR2 domain (6× Histidine disclosed as SEQ ID NO: 25), corresponding to amino acids 124-240 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM412176(US10398702, Example 15 | tert-Butyl (2R,5S)-4-[2-[...)
Affinity DataIC50:  3.80nMAssay Description:For the Bir2 assay, 3.5 nanomolar of 6× Histidine-tagged BIR2 domain (6× Histidine disclosed as SEQ ID NO: 25), corresponding to amino acids 124-240 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM412181((S)-N-(2-(((S)-3-((2,6- difluorophenyl)carbamoyl)-...)
Affinity DataIC50:  4nMAssay Description:For the Bir2 assay, 3.5 nanomolar of 6× Histidine-tagged BIR2 domain (6× Histidine disclosed as SEQ ID NO: 25), corresponding to amino acids 124-240 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM412182(US10398702, Example 21 | tert-Butyl (2R,5S)-4-[2-[...)
Affinity DataIC50:  4nMAssay Description:For the Bir2 assay, 3.5 nanomolar of 6× Histidine-tagged BIR2 domain (6× Histidine disclosed as SEQ ID NO: 25), corresponding to amino acids 124-240 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM242611((2S)-N-(1-((6-bromo-2- methoxynaphthalen-1-yl)meth...)
Affinity DataIC50:  4.99nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243177(US10053431, 75c)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243181(US10053431, 76d)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50441819(CHEMBL2436209 | US10053431, 89b)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM412165(N-(4-(((S)-3-((2,6- difluorophenyl)carbamoyl)- 2-(...)
Affinity DataIC50:  5nMAssay Description:For the Bir2 assay, 3.5 nanomolar of 6× Histidine-tagged BIR2 domain (6× Histidine disclosed as SEQ ID NO: 25), corresponding to amino acids 124-240 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM242641((S)-N-((S)-1-((5-bromo-2- methoxynaphthalen-1-yl)m...)
Affinity DataIC50:  5.11nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM242603((S)-N-((S)-5-(4-aminobenzoyl)-1-((6- bromo-2-metho...)
Affinity DataIC50:  5.68nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243119(US10053431, 89a)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM242682((S)—N—((S)-1-((5-Bromo-2-methoxynaphthal...)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50441833(CHEMBL2436334 | US10053431, 75b)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50441818(CHEMBL2436213 | US10053431, 75d)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243185(US10053431, 89d)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243188(US10053431, 90c)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50441832(CHEMBL2436205 | US10053431, 90d)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50441831(CHEMBL2436212 | US10053431, 91c)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM412163(N-(2-(((S)-3-((2,6- difluorophenyl)carbamoyl)- 2-(...)
Affinity DataIC50:  6nMAssay Description:For the Bir2 assay, 3.5 nanomolar of 6× Histidine-tagged BIR2 domain (6× Histidine disclosed as SEQ ID NO: 25), corresponding to amino acids 124-240 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM412178(US10398702, Example 17 | tert-Butyl N-[(1 S)-2-[[(...)
Affinity DataIC50:  6nMAssay Description:For the Bir2 assay, 3.5 nanomolar of 6× Histidine-tagged BIR2 domain (6× Histidine disclosed as SEQ ID NO: 25), corresponding to amino acids 124-240 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM412179(US10398702, Example 18 | tert-Butyl (2R,5S)-4-[2-[...)
Affinity DataIC50:  6nMAssay Description:For the Bir2 assay, 3.5 nanomolar of 6× Histidine-tagged BIR2 domain (6× Histidine disclosed as SEQ ID NO: 25), corresponding to amino acids 124-240 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50441834(CHEMBL2436330 | US10053431, 91a)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50441816(CHEMBL2436208 | US10053431, 41)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM242606((S)—N—((S)-5-(4-aminobenzoyl)-1-((6-brom...)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM242643((S)-N-((S)-1-((6-bromo-2- methoxynaphthalen-1-yl)m...)
Affinity DataIC50:  6.15nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM242595((S)-N-((S)-5-(4-acetylbenzoyl)-1-((1-(2- cyanophen...)
Affinity DataIC50:  6.28nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
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